Therapeutic Efficacy of Phacoemulsification and Intraocular Lens Implantation in Phacomorphic Glaucoma

PURPOSE: To evaluate the therapeutic efficacy of phacoemulsification in treating phacomorphic glaucoma. METHODS: We observed 25 eyes of 25 patients who had undergone phacoemulsification and intraocular lens implantation for the treatment of phacomorphic glaucoma. Intraocular pressure (IOP), best corrected visual acuity (BCVA), depth of anterior chamber, management and complications between preoperative and postoperative periods were analyzed retrospectively. RESULTS: The mean IOP was 49.0 +/- 10.6 mmHg (range: 31~70 mmHg) before the operation and 13.2 +/- 2.8 mmHg (range: 8~20 mmHg) at 36 months after surgery (Paired T-test, p<0.0001). We could not find any case with increased IOP in our series for more than 3 years. The postoperative IOP decreased significantly the day after surgery (Paired T-test, p<0.0001). Improvement of postoperative visual acuity was remarkable from the first week after operation (Paired T-test, p<0.0001). Postoperatively, the visual acuity was improved except for one eye with preoperative visual acuity of no light perception. Especially, BCVA in 15 cases (60%) was above 20/40. Preoperatively, the anterior chambers were extremely shallow (average: 1.5 +/- 0.3 mm) by the swollen lens, and the average postoperative anterior chamber depth increased significantly by 2.6 +/- 0.1 mm on A-scan. The ratio of lens thickness to axial length factor was 2.5 +/- 0.1, indicating the shallow anterior chamber. Continuous postoperative medical treatment for IOP control was needed in one case, where peripheral anterior synechiae were observed by gonioscopy immediately after surgery. CONCLUSIONS: Phacoemulsification is a very safe and effective procedure for the treatment of phacomorphic glaucoma.

Clinical Results of Primary Posterior Continuous Curvilinear Capsulorhexis

PURPOSE: To evaluate the outcome of posterior continuous curvilinear capsulorhexis (PCCC) performed simultaneously with cataract surgery to inhibit after-cataract. METHODS: Among patients who underwent phacoemulsification and posterior chamber intraocular lens implantation from December 1999 through December 2001, we had followed on 94 eyes of 80 patients who underwent PCCC intraoperatively and 100 eyes in 92 patients without PCCC as control group. Both groups were divided into 4 categories: nonproliferative diabetic retinopathy(NPDR); uveitis; below 60 years without ocular and systemic disease; over 60 years without ocular and systemic disease. Preoperative and postoperative visual acuity and complications were analyzed from 6 months to 12 months. RESULTS: There was statistically no difference in the best corrected visual acuity at 6 months between PCCC and control group in all categories. Transient increase in the intraocular pressure was noted in 5 eyes (5%) of PCCC group and 3 eyes (3%) in control group. Vitreous prolapse into anterior chamber was found in 2 eyes (2%) of PCCC group. Cystoid macular edema was found in only 1 eye (1%) in NPDR patients of PCCC group. Progression of diabetic retinopathy was found in 1 eye (5.6%) and 3 eyes (12.5%) in each group respectively. There was no statistically significant difference in progression of diabetic retinopathy after surgery between the two groups. CONCLUSIONS: Primary PCCC is a safe procedure to perform in patient who has a predisposition to after-cataract.

Comparison of Complications of the Corneal Flap following LASIK by Three Different Manual Microkeratomes

PURPOSE: To compare and analyze intraoperative and postoperative complications of corneal flap in the LASIK procedures using different types of manual microkeratomes (MLK, LSK, disposable Barron). METHODS: Eight hundred sixty-two eyes were retrospectively evaluated to study the effects of 3 different microkeratomes on the frequency of complications, managements, and postoperative best visual acuity. The eyes were grouped according to the microkeratomes used in making corenal flap: Group 1 (334 eyes) treated with MLK(SCMD, USA); Group 2 (256 eyes), LSK(Moria, France); Group 3 (272 eyes), disposable Barron(Katena, USA). RESULTS: Mean follow-up period was 6.3 months and mean age was 29.2 years (range 20 39). Complications of corneal flap were observed in 74(7.9%) of 862 eyes. Intraoperative flap complications occurred in 15 eyes (4.5%), 6 eyes (2.4%) and 3 eyes (1.2%) in each group, respectively. The postoperative flap complications were observed in 24 eyes (7.2%), 17 eyes (6.7%) and 9 eyes (3.3%) in each group. The postoperative best corrected visual acuity decreased by 2 lines or more in 2 eyes (0.6%), 1 eye (0.4%) and none (0%) of each group. CONCLUSIONS: The incidence of corneal flap-related complications by manual microkeratomes was relatively low. Disposable Barron microkeratome showed the lowest complication rate in our series. It also has an advantage of easy maneuverability, and reproducibility (equal size and thickness of corneal flap).

MRI Findings of Traumatic Spinal Subdural Hematoma

PURPOSE: To describe the MR imaging findings of traumatic spinal subdural hematoma. MATERIALS AND METHODS: We retrospectively reviewed the MR images of six patients, with symptoms of acute spinal cord or cauda equena compression after trauma, together with spinal subdural hematoma. We analysed the extent, location, configuration and signal intensity of the lesions. RESULTS: In five of six cases, hematomas were distributed extensively throughout the thoracolumbosacral or lumbosacral spinal levels. In five cases they were located in the dorsal portion of the thecal sac, and in one case, in the ventral portion. On axial images, hematomas showed a concave or convex contour, depending on the amount of loculated hematoma. A lobulated appearance was due to limitation of free extension of the hematoma within the subdural space at the lateral sites (nerve root exist zone) at whole spine levels, and at the posteromedian site under lumbar 4-5 levels. CONCLUSION: In cases of spinal subdural hematoma, the lobulated appearance of hematoma loculation in the subdural space that bounds the lateral sites at all spinal levels and at the posteromedian site under L4-5 levels is a characteristic finding.

Cross-calibration of Bone Mineral Density between Two Different Dual X-ray Absorptiometry Systems: Hologic QDR 4500-A and Lunar EXPERT-XL / 대한핵의학회잡지

PURPOSE: A cross-calibration equation is needed to compare bone mineral density measured by different dual X-ray absoptiometry systems. We performed this study to establish appropriate cross-calibration equations between two different dual X-ray absorptiometry systems. MATERIALS AND METHODS: Bone mineral density of anterior-posterior lumbar spine (L2-4 level) and femoral neck were measured in 109 women (55+/-11yr) using two different dual X-ray absorptiometry systems (Lunar EXPERT-XL) and Hologic QDR 4500-A). Bone mineral density values measured by two systems, including area, bone mass content, bone mineral density and percentile of young normals were compared and cross-calibration equations between two systems derived. RESULTS: The bone mineral density values of 109 women measured by Lunar system were 0.958+/-0.17 g/cm2 at L2-4 and 0.768+/-0.131 g/cm2 at femur neck, which were significantly higher (13+/-6% at L2-4 and 19+/-7% at femur neck, p0.05). There was a high correlation between bone mineral density values of L2-4 and femoral neck obtained with both dual X-ray absortiometry systems (r=0.96 and 0.95, respectively). Cross-calibration equations relating the bone mineral density were Lunar=1.1287xHologic-0.0027 for L2-4 and Lunar=l.1556xHologic+0.0l82 for femoral neck. CONCLUSION:: We obtained cross-calibration equations of bone mineral density between Lunar EXPERT-XL and Hologic QDR 4500-A. These equations can be useful in comparing bone mineral density obtained by different dual X-ray absorptiometry systems.

Effect of Degenerative Change of Lumbar Spine on Lateral Bone Mineral Density Measurement Using Dual EnergyX-ray Absorptiometry: Usefulness of Measurement in the Supine Lateral Projection

PURPOSE: To evaluate the usefulness of supine lateral bone mineral density (BMD) measurement using DXA bycomparing AP and lateral spine BMD in patients with degenerative change. MATERIALS AND METHODS: Six hundred andseventy-two women underwent AP and lateral BMD measurement of L-spine, using DXA. Spur changes and end-platesclerosis were considered as degenerative change, and osteoporosis was defined according to WHO criteria. Theratio of mid-lateral BMD to AP BMD was calculated and the differences in ratio were analyzed in the degenerativegroup and controls, according to aging and osteoporosis, using the t test and ANOVA. The correlation coefficiencybetween aging and AP BMD and lateral BMD, respectively, was calculated. RESULT: The mLat/AP ratio in the controland degenerative group was 0.710(0.005 / 0.622(0.028 (p=0.003) in the 40-49-year-old group, 0.663(0.006 /0.612(0.016 (p=0.002) in the 50-59-year-old group, 0.626(0.015 / 0.552(0.023 (p=0.007) in the 60-69 year-oldgroup, and 0.717(0.028 / 0.600(0.045 (p=0.076) in those aged over 70. The ratio was 0.656(0.015 / 0.598(0.038(p=0.099) in osteoporosis, 0.684(0.008 / 0.596(0.016 (p=0.000) in osteopenia, and 0.688(0.005 / 0.583(0.019(p=0.000) in normal subjects, showing that lateral BMD is more sensitive than AP BMD, especially in thedegenerative group. There was negative correlation between aging and AP BMD(r= -0.545), lateral BMD(r= -0.571),and mid-lateral BMD(r=-0.583). CONCLUSION: In a selective group of patients with degenerative change, supinelateral BMD measurement of L-spine is useful.

Can Anterior Junction Line be Used to Distinguish Right Middle from Right Upper Lobe on CT Scan?

PURPOSE: To evalvate the usefulness on a CT chest scan, of the anterior junction line as an anatomical landmark to distinguish the right middle and the right upper lobe MATERIALS AND METHODS: We found that the anterior junction line has a constant anatomical relationship with the right upper and middle lobe, and with this in mind, analysed connvcntional CT films of 86 patients with normal lung (group A) and 30 with architectural distortion (group B). On a series of slices, we compared the location of slice 1 with that of slice 2 (slice 1: the slice which includes the lowest portion of the anterior junction line, slice 2: the initial slice, in which the right middle lobe occupies the whole of the lung anterior to the right major fissure). RESULTS: In group A (n=86), the right upper lobe, as seen in the anteromedial zone of slice 1, was present in 83 cases (96.5%). The right upper lobe on slice 1 was absent in two cases (2.3%) in which a minor fissure was almost completely abent. In group B (n=30), the right upper lobe on slice 1 was absent in 19 cases (63.3%). CONCLUSION: We suggest that on a CT chest scan, the anterior junction line can be used as an anatomical landmark in the differentiation of the right middle from the right upper lobe, and as an indicator of the presence of architectural distortion.