Study on the correlation between home rearing environment and social emotional competence of infants and toddlers / 中国儿童保健杂志

【Objective】 To understand the current situation of social emotional competence of infants and toddlers, and analyze its relationship with home rearing environment, in order to provide the basis for improving the level of infant social emotional development. 【Method】 A study was conducted on 390 individuals from a child health institution in Hubei and Henan provinces.The "Infant and Toddler Social-Emotional Assessment Scale" and "1 - 3 Years Child Home Rearing Environment Scale" were used to investigate the social emotions ability and home rearing environment of infants and toddlers. 【Results】 A total of 390 valid questionnaires were collected in this survey, of which 199 were boys (51.0%) and 191 girls (49.0%). The average age of infants was (27.13±6.86)months.The age distribution is mainly among infants and young children aged 24 to 36 months, with a total of 305 people (78.2%). The caregiver′s registered residence (Z=-3.570), father′s education level (H=17.106), mother′s education level (H=7.980), per capita monthly income of the family (H=13.986), and the home rearing environment (Z=-8.881) had statistical significance on the social emotional competence of infants(P<0.05 or <0.01).There was a significant positive correlation between family rearing environment and infants′ social emotion (r=0.582, P<0.01).Multiple regression analysis showed that the social adaptation/self-care(β=0.30, 95%CI: 0.18 - 0.52, P<0.01)and language cognition dimensions(β=0.22, 95%CI: 0.07 - 0.59, P<0.05) in the home rearing environment had a statistically significant impact on the social emotional ability of infants and toddlers. 【Conclusion】 The home rearing environment is closely related to the social emotional development of infants and young children.Improve the parenting knowledge and skills of the main caregivers of infants and young children, build a good family rearing environment for infants and young children, which is beneficial to promote the development of children′s social emotions.

Correlation of parental meta-emotion philosophy and family rearing environment in infants and toddlers / 中国儿童保健杂志

【Objective】 To explore the relationship between parental meta-emotion philosophy and family rearing environment in infants and toddlers, in order to provide guidance for building a positive family rearing environment. 【Methods】 The Parental Meta-Emotion Philosophy Scale was used to measure parents′ social emotions. Family rearing environment of infants was investigated by combining demographic data and Family Rearing Environment Scale. Independent sample t-tests, one-way analysis of variance, Spearman correlation analysis, and multiple linear regression were utilized to analyze the relationship between parental meta-emotion philosophy and the family rearing environment. 【Results】 A total of 370 infant caregivers were included in the study. The average age of infants was (27.81±7.76) months, with 192 boys (51.9%) and 178 girls (48.1%). Parents′ education level (F=4.71), whether they were the only child or not (t=8.85), whether the infant attended nursery or not (t=-2.49), and the per capita monthly income of the family (F=4.77) showed statistical significance in relation to the differences observed among the family rearing environments of infants and toddlers (P<0.05). Multivariate analysis indicated that the emotional teaching dimension of parental meta-emotion philosophy had a positive predictive effect on the overall level of the infant′s family rearing environment (β=0.50, 95%CI: 1.11 - 1.59), while the emotional loss dimension had a negative predictive effect (β=-0.15, 95%CI: -0.85 - -0.07). 【Conclusion】 The parental meta-emotion philosophy is closely related to the family rearing environment and serves as an important factor influencing it. It is supposed to improve parents′ emotional literacy and enrich their knowledge of parental meta-emotion philosophy, so as to help build a positive family rearing environment.

Application of"zero channel"emergency mode in patients with severe traumatic brain injury / 中国现代医生

Objective To investigate the effect of"zero channel"emergency mode on the treatment of patients with severe traumatic brain injury.Methods A total of 147 patients with severe traumatic brain injury admitted to the Second Hospital of Jiaxing from January 2020 to December 2021 were selected as study objects.Sixty-two patients hospitalized in traditional emergency mode from January to December 2020 were included in control group,and 85 patients hospitalized in"zero channel"emergency mode from January to December 2021 were included in observation group.The initiation time of rescue,completion time of CT examination,completion time of blood transfusion,duration of operation,clinical prognosis and complication rate were compared between two groups.Results The initiation time of rescue,completion time of CT examination,completion time of blood transfusion,and duration of operation in observation group were significantly shorter than those in control group(P<0.05).The proportion of good recovery in observation group was significantly higher than that in control group(68.20%vs.38.70%,χ2=12.671,P<0.001).The complication rate of observation group was significantly lower than that of control group(21.18%vs.80.65%,χ2=51.000,P<0.001).Conclusion"Zero channel"emergency mode can effectively shorten the treatment time of patients with severe traumatic brain injury,improve the success rate of rescue,reduce the incidence of complications,worthy of clinical use and promotion.

Association between triglyceride-glucose index (TyG) and the risk of new-onset stroke in middle-aged and elderly people / 公共卫生与预防医学

Objective The high incidence, disability, and mortality rates of stroke result in a heavy economic and social burden. The aim of this study was to investigate the relationship between triglyceride-glucose (TyG) index and new-onset stroke to assist in the identification of high-risk groups for stroke and to provide ideas for effective prevention. Methods The study was based on data from the China Health and Retirement Longitudinal Study (CHARLS) from 2011 to 2018 and included 7630 eligible middle-aged and elderly participants. The association between TyG index and new-onset stroke was assessed by logistic regression modelling and restricted triple spline analysis. Results A total of 431 participants had a new stroke. The TyG index was found to be a risk factor for stroke occurrence when it was >8.523, and there was a positive linear association moderated by gender. Conclusion Elevated TyG index is a risk factor for new stroke. This study provides new ideas for the identification of high-risk groups for stroke and for intervention measures and timing.

Site-directed mutagenesis enhances the activity of benzylidene acetone synthase of polyketide synthase from Polygonum cuspidatum / 生物工程学报

Polygonum cuspidatum polyketide synthase 1 (PcPKS1) has the catalytic activity of chalcone synthase (CHS) and benzylidene acetone synthase (BAS), which can catalyze the production of polyketides naringenin chalcone and benzylidene acetone, and then catalyze the synthesis of flavonoids or benzylidene acetone. In this study, three amino acid sites (Thr133, Ser134, Ser33) that may affect the function of PcPKS1 were identified by analyzing the sequences of PcPKS1, the BAS from Rheum palmatum and the CHS from Arabidopsis thaliana, as well as the conformation of the catalytic site of the enzyme. Molecular modification of PcPKS1 was carried out by site-directed mutagenesis, and two mutants were successfully obtained. The in vitro enzymatic reactions were carried out, and the differences in activity were detected by high performance liquid chromatography (HPLC). Finally, mutants T133LS134A and S339V with bifunctional activity were obtained. In addition to bifunctional activities of BAS and CHS, the modified PcPKS1 had much higher BAS activity than that of the wild type PcPKS1 under the conditions of pH 7.0 and pH 9.0, respectively. It provides a theoretical basis for future use of PcPKS1 in genetic engineering to regulate the biosynthesis of flavonoids and raspberry ketones.

Iodine nutrition status of pregnant women in Ningxia Hui Autonomous Region from 2017 to 2020 / 中华地方病学杂志

Objective:To analyze and compare the salt iodine content and iodine nutrition status of pregnant women in Ningxia Hui Autonomous Region (Ningxia for short), and to provide basis for formulation of prevention and control measures.Methods:From 2017 to 2020, 100 pregnant women were surveyed each year in 22 counties (cities, districts) in Yinchuan, Shizuishan, Wuzhong, Guyuan and Zhongwei of Ningxia, salt samples and urine samples were collected for salt iodine and urinary iodine detection.Results:Totally 8 807 salt samples were collected, the median salt iodine was 24.6 mg/kg. The qualified rate of iodized salt was 91.59% (7 838/8 558), the coverage rate of iodized salt was 97.17% (8 558/8 807), and the consumption rate of qualified iodized salt was 89.00% (7 838/8 807). The consumption rate of qualified iodized salt increased year by year (χ 2trend = 248.47, P < 0.001). There were statistical differences in salt iodine levels in different years and regions ( H = 259.14, 37.09, P < 0.001). Totally 8 107 urine samples were collected, the median urinary iodine of pregnant women was 165.00 μg/L, which reached the appropriate level. The median and composition of urinary iodine were statistically different in different regions and pregnancies ( H = 28.87, 17.91, P < 0.001; χ 2 = 85.89, 20.59, P < 0.05). Conclusions:The coverage rate of iodized salt among pregnant women in Ningxia is high, and the urinary iodine level is generally in a suitable state. However, for pregnant women at risk of iodine deficiency, special attention should be paid and targeted iodine supplementation measures should be taken.

Risk factors and countermeasures of depression in acute stroke patients in Wuhan / 公共卫生与预防医学

Objective To explore the risk factors and countermeasures of depression in stroke patients in Wuhan. Methods A stratified cluster sampling method was used to randomly select 628 hospitalized patients at acute stage of stroke in Wuhan from June 2019 to June 2020. According to HAMD score, the patients were divided into normal group (n=381) and post-stroke depression group (n=247). The risk factors of depression in stroke patients were analyzed by Logistic regression using self-made questionnaire, including gender, age, education level, stroke type, residence, patient compliance to treatment, NIHSS score, ADL score and independent walking, and early intervention measures were proposed. Results Univariate analysis showed that education level, family burden, NIHSS score, ADL score and independent walking were related to the occurrence of depression in stroke patients (P<0.05). Logistic multivariate regression analysis showed that, NIHSS score, ADL score and independent walking were correlated with depression in patients at acute stage after stroke (P<0.05). Conclusion the risk of depression in patients with acute cerebral apoplexy is higher, the patients' adherence to treatment, NIHSS score, ADL scores, situation of independent walking is a cause of depression in patients with cerebral apoplexy risk factors, should improve patients' adherence to treatment as soon as possible and daily life ability, improve nerve function, should pay attention to its early intervention.

Constructing a scale on KAP of nurses ′ on stroke-dysphagia and test of its reliability and validity / 中国实用护理杂志

Objective:To develop a rating scale on the knowledge, attitude and practice of stroke-dysphagia for nurses, and to test the reliability and validity.Methods:Based on theoretical framework of the Knowledge, Attitude, Practice (KAP), the scale items were determined through literature review, expert consultation, pre-investigation, and qualitative interviews. 633 nurses in the department of stroke that from 18 hospitals in Hubei Province were selected for the survey, to further screen the items and test reliability and validity of the scale.Results:The positive coefficient of the two-round expert consultation were both 100%; the expert authority coefficient was 0.930; the level of coordination of experts ′ opinions was good. Exploratory factor analysis extracted 4 factors, the accumulative variance contribution rate was 44.278%, Content validity index S-CVI was 0.984, I-CVI was 0.857-1.000; the Cronbach α coefficient of scale was 0.855, test-retest reliability was 0.909. Eventually, the scale was consisted of 3 dimensions, 32 items. Conclusion:The scale has good reliability and validity, and can be used as a survey tool to test the current knowledge, attitude, practice of clinical nurses about patient with stroke-dysphagia.

The Progression of SARS Coronavirus 2 (SARS-CoV2): Mutation in the Receptor Binding Domain of Spike Gene

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) is a positive-sense singlestranded RNA (+ssRNA) that causes coronavirus disease 2019 (COVID-19). The viral genome encodes twelve genes for viral replication and infection. The third open reading frame is the spike (S) gene that encodes for the spike glycoprotein interacting with specific cell surface receptor – angiotensin converting enzyme 2 (ACE2) – on the host cell membrane. Most recent studies identified a single point mutation in S gene. A single point mutation in S gene leading to an amino acid substitution at codon 614 from an aspartic acid 614 into glycine (D614G) resulted in greater infectivity compared to the wild type SARS-CoV2. We were interested in investigating the mutation region of S gene of SARS-CoV2 from Korean COVID-19 patients. New mutation sites were found in the critical receptor binding domain (RBD) of S gene, which is adjacent to the aforementioned D614G mutation residue. This specific sequence data demonstrated the active progression of SARS-CoV2 by mutations in the RBD of S gene.The sequence information of new mutations is critical to the development of recombinant SARS-CoV2 spike antigens, which may be required to improve and advance the strategy against a wide range of possible SARS-CoV2 mutations.

The Progression of SARS Coronavirus 2 (SARS-CoV2): Mutation in the Receptor Binding Domain of Spike Gene

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) is a positive-sense singlestranded RNA (+ssRNA) that causes coronavirus disease 2019 (COVID-19). The viral genome encodes twelve genes for viral replication and infection. The third open reading frame is the spike (S) gene that encodes for the spike glycoprotein interacting with specific cell surface receptor – angiotensin converting enzyme 2 (ACE2) – on the host cell membrane. Most recent studies identified a single point mutation in S gene. A single point mutation in S gene leading to an amino acid substitution at codon 614 from an aspartic acid 614 into glycine (D614G) resulted in greater infectivity compared to the wild type SARS-CoV2. We were interested in investigating the mutation region of S gene of SARS-CoV2 from Korean COVID-19 patients. New mutation sites were found in the critical receptor binding domain (RBD) of S gene, which is adjacent to the aforementioned D614G mutation residue. This specific sequence data demonstrated the active progression of SARS-CoV2 by mutations in the RBD of S gene.The sequence information of new mutations is critical to the development of recombinant SARS-CoV2 spike antigens, which may be required to improve and advance the strategy against a wide range of possible SARS-CoV2 mutations.

Clinical observation of cluster sedation and analgesia for patients with mechanical ventilation / 中国基层医药

Objective To investigate the effect of cluster sedation and analgesia for patients with mechanical ventilation.Methods From June 2016 to June 2017,234 patients with mechanical ventilation admitted to the ICU of the Second Hospital of Jiaxing were selected and divided into study group (120 cases) and control group (114 cases) according to the random number method.The control group received conventional nursing ,while the study group was given cluster sedation and analgesia.The drug use dose,mechanical ventilation time ,ICU admission time, sputum incidence and 1－month survival rate were compared between the two groups.Results The total dose and unit dose in the study group were lower than those in the control group [(252.17 ±38.42) mg vs.(326.50 ±50.88) mg, (60.50 ±9.33)μg· kg －1· h－1 vs.(79.41 ±10.52)μg· kg－1· h－1 ,t＝12.562,14.564,P＝0.000,0.000].The duration of mechanical ventilation and ICU stay in the study group were also shorter than those in the control group [(5.13 ±0.73)d vs.(7.57 ±0.95) d,(7.02 ±0.91) d vs.(10.55 ±1.26) d,t＝21.949,24.460,P＝0.000, 0.000].The incidence rate of delirium in the study group was lower than that in the control group (28.33% vs. 50.88%,χ2 ＝12.453,P＝0.000).The 1－month survival rate of the study group was higher than that of the control group (91.67%vs.80.70%,χ2 ＝5.954,P＝0.015).Conclusion Cluster sedation and analgesia is an effective method for ICU mechanical ventilation patients , which can improve the quality of medical and nursing , and is an important embodiment in critical medical management ,it is worthy of attention in intensive care workers.

Analysis of investigation results of iodine content of drinking water of residents in Ningxia Hui Autonomous Region in 2017 / 中华地方病学杂志

Objective@#To understand the iodine content of drinking water in Ningxia, and provide a basis for promoting scientific iodine supplementation.@*Methods@#In 2017, 22 counties (cities, districts) of Ningxia Hui Autonomous Region were surveyed by township (town, street office) as the unit. Water samples were collected and iodine content was detected according to the unified centralized water supply, mixed water supply and all the scattered water supply methods. Among them, the investigation at township (town and street office) level found that the median of iodine in water was > 10 μg/L, and then the water samples were collected in administrative villages (neighborhood committees) and the content of iodine in water was detected.@*Results@#A total of 242 townships (town, street office) were surveyed at the township level water iodine, and a total of 1 048 water samples were collected, the median water iodine was 6.6 μg/L, the range was 0.0-97.8 μg/L. There were 75 townships with a median water iodine > 10 μg/L, and an administrative village level water iodine survey was conducted. A total of 1 169 water samples were collected, the median water iodine was 14.5 μg/L, and the range was 0.0-97.4 μg/L. The median water iodine at the township level, unified centralized water supply, mixed water supply, and all the scattered water supply was 6.9, 6.8, and 4.5 μg/L, respectively. The difference was statistically significant (χ2 = 7.08, P < 0.05). The median water iodine at the administrative village level, unified centralized water supply, mixed water supply, and all the scattered water supply was 15.8, 8.4, and 11.6 μg/L, respectively. The difference was statistically significant (χ2 = 35.23, P < 0.05).@*Conclusion@#The iodine content of drinking water in Ningxia residents is low, which is consistent with the fact that Ningxia is in the iodine deficient area.

Clinical observation of cluster sedation and analgesia for patients with mechanical ventilation / 中国基层医药

Objective@#To investigate the effect of cluster sedation and analgesia for patients with mechanical ventilation.@*Methods@#From June 2016 to June 2017, 234 patients with mechanical ventilation admitted to the ICU of the Second Hospital of Jiaxing were selected and divided into study group (120 cases) and control group (114 cases) according to the random number method.The control group received conventional nursing, while the study group was given cluster sedation and analgesia.The drug use dose, mechanical ventilation time, ICU admission time, sputum incidence and 1-month survival rate were compared between the two groups.@*Results@#The total dose and unit dose in the study group were lower than those in the control group [(252.17±38.42)mg vs.(326.50±50.88)mg, (60.50±9.33)μg·kg-1·h-1 vs.(79.41±10.52)μg·kg-1·h-1, t=12.562, 14.564, P=0.000, 0.000]. The duration of mechanical ventilation and ICU stay in the study group were also shorter than those in the control group [(5.13±0.73)d vs.(7.57±0.95)d, (7.02±0.91)d vs.(10.55±1.26)d, t=21.949, 24.460, P=0.000, 0.000]. The incidence rate of delirium in the study group was lower than that in the control group (28.33% vs.50.88%, χ2=12.453, P=0.000). The 1-month survival rate of the study group was higher than that of the control group (91.67% vs.80.70%, χ2=5.954, P=0.015).@*Conclusion@#Cluster sedation and analgesia is an effective method for ICU mechanical ventilation patients, which can improve the quality of medical and nursing, and is an important embodiment in critical medical management, it is worthy of attention in intensive care workers.

Analysis of investigation results of iodine content of drinking water of residents in Ningxia Hui Autonomous Region in 2017 / 中华地方病学杂志

Objective To understand the iodine content of drinking water in Ningxia,and provide a basis for promoting scientific iodine supplementation.Methods In 2017,22 counties (cities,districts) of Ningxia Hui Autonomous Region were surveyed by township (town,street office) as the unit.Water samples were collected and iodine content was detected according to the unified centralized water supply,mixed water supply and all the scattered water supply methods.Among them,the investigation at township (town and street office) level found that the median of iodine in water was ＞ 10 μg/L,and then the water samples were collected in administrative villages (neighborhood committees) and the content of iodine in water was detected.Results A total of 242 townships (town,street office) were surveyed at the township level water iodine,and a total of 1 048 water samples were collected,the median water iodine was 6.6 μg/L,the range was 0.0-97.8 μg/L.There were 75 townships with a median water iodine ＞ 10 μg/L,and an administrative village level water iodine survey was conducted.A total of 1 169 water samples were collected,the median water iodine was 14.5 μg/L,and the range was 0.0-97.4 μg/L.The median water iodine at the township level,unified centralized water supply,mixed water supply,and all the scattered water supply was 6.9,6.8,and 4.5 μg/L,respectively.The difference was statistically significant (x2 =7.08,P ＜ 0.05).The median water iodine at the administrative village level,unified centralized water supply,mixed water supply,and all the scattered water supply was 15.8,8.4,and 11.6 μg/L,respectively.The difference was statistically significant (x2 =35.23,P ＜ 0.05).Conclusion The iodine content of drinking water in Ningxia residents is low,which is consistent with the fact that Ningxia is in the iodine deficient area.

Anxiety life interference among primary and middle school students in Henan Province and its influencing factors / 中国学校卫生

Objective@#To investigate anxiety life interference among primary and middle school students in Henan Province and its influencing factors, and to provide scientific basis for health education in primary and secondary school students.@*Methods@#By using cluster sampling method, 3 573 primary school students and 2 748 secondary school students in Henan Province were investigated with Child Anxiety Life Interference Scale(CALIS), Resilience Scale for Chinese Adolescents(RSCA), Perceived Social Support Scale(PSSS), Self-Esteem Scale(SES), General Self-efficacy Scale(GSES).@*Results@#There were significant differences in anxiety life disturbance in primary and middle school students by gender(t=2.07, P=0.04), school level(t=-2.29, P=0.02), degree of anxiety(F=119.93, P<0.01), educational level of fathers (F=13.38, P<0.01) and educational level of mothers(F=9.65, P<0.01). The degree of life disturbance caused by anxiety was negatively correlated with mental resilience, social support and self-efficacy(r=-0.25, -0.09, -0.12, P<0.01), and was positively related to self-esteem(r=0.23). Mental resilience (β=-0.21) significantly negatively predicted anxiety interference with life, while self-esteem (β=0.13) and social support (β=0.06) significantly positively predicted anxiety interference with life.@*Conclusion@#The life of primary and middle school students is seriously disturbed by anxiety, and mental resilience is the primary psychosocial factor that affects the level of anxiety life interference among primary and middle school students.

Mediation of psychological vulnerability in the association between stressful life events and psychological crisis among college students / 中国学校卫生

Objective@#To explore the psychological vulnerability in the relationship between stressful life events and psychological crisis, and to provide basis for psychological crisis prevention among college students.@*Methods@#With stratified cluster sampling，3584 students in Weifang Medical University and Weifang University were selected for a crosssectional selfadministrated questionnaire survey in December 2017. A selfdesigned general questionnaire, Adolescent SelfRating Life Events Check List(ASLEC), psychological vulnerability scale, and psychological crisis performance questionnaire for college students were applied in the survey. Mediating effect was tested by using SPSS 23.0 and AMOS 23.0.@*Results@#The average score was 36.53±8.58 for life events(ASLEC), 54.21±11.80 for psychological vulnerability,and 26.33±39.72 for psychological crisis performance. The life events score was positively correlated with psychological crisis score (r=0.54, P<0.05) and positively correlated with psychological vulnerability score(r=0.30, P<0.05); psychological vulnerability score was positively correlated with psychological crisis score(r=0.37, P<0.05). Psychological vulnerability played a partial intermediary role on the relationship between life events and psychological among undergraduates,the effect was 0.10 accounting for 15.13% of the total effect.@*Conclusion@#Life events have made a direct influence and an indirect influence mediated by psychological crisis vulnerability on psychological crisis among undergraduates.

Study of Shenling-Baizhu granule combined with saccharomyces boulardii treatment for pediatric antibiotic associated diarrhea / 国际中医中药杂志

Objective To observe Shenling-Baizhu granule combined with saccharomyces boulardii treatment for pediatric antibiotic associated diarrhea (AAD). Methods A total of 146 children with AAD were randomly divided into the control group (n=73) and the observation group (n=73). The control group received the saccharomyces boulardii, and the observation group received saccharomyces boulardii and Shenling-Baizhu granule, with a course of 5 days. The CD4 and CD8 T lymphocytes were detected by flow cytometry. The stool frequency, stool frequency recovery time, and clinic effects were compared. Results The stool frequency (3.0 ± 0.4 times/d vs. 3.6 ± 0.4 times/d, t=2.624), stool frequency recovery time (3.2 ± 0.6 d vs. 4.5 ± 0.8 d, t=2.641), and recovery time (4.1 ± 0.8 d vs. 5.3 ± 1.1 d, t=2.522) in observation group were significantly lower than those in control group ( P＜0.05). After the treatment, the CD4+(38.65% ± 5.74% vs. 33.72% ± 5.23%, t=2.452), CD4+/CD8+(1.92 ± 0.38 vs. 1.45 ± 0.26, t=2.483) of the observation group was significantly higher than those of the control group, and the CD8+(20.15% ± 3.16% vs. 23.21% ± 3.44%, t=2.483) of the observation group was significantly lower than this of the control group (P＜0.05). The rate of clinic effects was 93.2% (68/73) in observation group, which was higher than 80.8% (59/73) in control group (χ2=2.446, P＜0.05). Conclusions The Shenling-Baizhu granule combined with saccharomyces boulardii could enhance the immune function in children with AAD with significant clinical efficacy.

Investigation on the significance of pressure pain thresholds before and after treatment in female with myofascial chronic pelvic pain / 中国医师进修杂志

Objective To explore the therapeutic effect and clinical significance of pelvic floor rehabilitation technique in female with myofascial chronic pelvic pain (MCPP) by detecting the pressure pain thresholds (PPTs). Methods One hundred healthy female (control group) and 324 female MCPP patients (observation group) from January 2009 to December 2016 were selected. Automatic body surface and vaginal pressure pain detector was applied to detect two groups′PPTs of the 34 spots. The difference of PPTs at each spot was analyzed in two groups. In addition, 51 patients with moderate and severe MCPP were selected to record the changes of PPTs and pain scores before and after the treatment of pelvic floor rehabilitation technique. Results The average PPTs of the abdomen, vulva, pelvic floor and vaginal front and back fornix, bilateral adnexa uteri and sacrouterine ligament in the observation group were significantly lower than those in the control group (P<0.01 or<0.05). The average PPTs of the abdomen, vulva, pelvic floor muscles and vaginal front and back fornix, bilateral adnexa uteri and sacrouterine ligament of 51 MCPP patients after treatment were significantly higher than those before treatment (P<0.01). After treatment, PPTs and pain scores of the pelvic floor muscles, bilateral adnexa uteri, bilateral sacrouterine ligament, bilateral sacral spine ligament and vaginal front and back fornix were negatively correlated (r =- 0.78 to- 0.19, P = 0.01 to 0.04); there was a negative correlation between the PPTs and pain scores of the left and right latissimus dorsi (r=-0.28, P=0.04;r=-0.32, P=0.02). The complete remission rate with the pelvic floor rehabilitation technique in 51 patients with MCPP was 9.8％(5/51), the significant remission rate was 90.2％(46/51), and the total remission rate was 100.0％ (51/51). Conclusions Compared with the normal healthy ones, female with MCPP has lower PPTs in the abdomen, perineum, vagina and pelvic floor. The effect of pelvic floor rehabilitation technique on MCPP is well, which can increase patients′PPTs to reduce pain scores. It is a worthwhile method to treat these diseases.

Observation on therapeutic effect of application of aerosol inhalation of Scutellaria baicalensis in fine nursing care model for prevention of ventilator-associated pneumonia / 中国中西医结合急救杂志

Objective To approach the nursing experience and clinical therapeutic effect of using aerosol inhalation of Scutellaria baicalensis leachate to prevent occurrence of ventilator-associated pneumonia (VAP) in critically ill patients in intensive care unit (ICU). Methods Ninety-two severe patients who received mechanical ventilation (MV) in ICU of Hangzhou Geriatric Hospital from April 2016 to August 2017 were enrolled, and they were divided into a test group and a control group according to their wishes and self-selection, 46 cases in each group. The patients in both groups were given fine nursing care model, in the control group aerosol inhalation of physiological saline was used; in the test group aerosol inhalation of Scutellaria baicalensis leachate was applied. The incidence of VAP, the duration of MV and time of ICU stay were compared between the two groups. Results Compared to the control group, the total incidence of VAP, duration of MV, time of ICU stay in the test group were significantly lower than those in control group [total incidence of VAP: 17.39% (8/46) vs. 36.95% (17/46), duration of MV (days): 11.37±5.23 vs. 15.21±5.93, time of ICU stay (days): 18.54±5.92 vs. 27.33±5.27, all P < 0.05]. Conclusion Under the fine nursing care pattern, compared with the aerosol inhalation of saline, the aerosol inhalation of Scutellaria baicalensis leaching can be more effectively to prevent VAP in ICU critically ill patients and reduce their duration of MV and of ICU stay, so the latter one's clinical therapeutic effect is better.

Worry about ill consequences in cancer patients and its relationship with depression / 重庆医学

Objective To understand the worry situation about ill consequences in cancer patients and its relationship with depression.Methods The inpatients with cancer were extracted from 4 general hospitals of Wuhan and Beijing city by the cluster sampling.The self-designed questionnaires were adopted to survey the worry situation about ill consequences in cancer patients.The self-rating depression scale (SDS) was used to assess the patients' depression status.Results A total of 485 cancer patients were surveyed,including 204 males (42.1 ％),281 females(57.9 ％),and the mean age was (56.59 ± 11.19)years old.More than half of the patients usually or always worried about medical expenses.Worries about not taking care of their children,losing their lives,physical disability,leaving sequela and losing life ability also happened a lot.Patients worried more about losing their life,the possibility appearing depression was greater (P＜0.05).The younger the patients were,the greater the depression possibility was;the company staffs had lower risk of depression compared with those whose occupation was others (P＜0.05).Conclusion Cancer patients have different degrees of worries about ill consequences such as medical expenses,not taking care of their children and losing their lives and their worries about losing their lives could affect their depression status.