1.
Braz. j. med. biol. res
; 27(11): 2639-43, Nov. 1994. ilus
Artigo
em Inglês
| LILACS
| ID: lil-153986
RESUMO
the subcellular localization in brain of an unconventional, calmodulin-binding myosin (myosin-V) found in neurons, astrocytes and other secretory cells of vertebrates has been investigated by probing Western blots of synaptic fractions from rat cerebral cortex with affinity-purified polyclonal antibodies against myosin-V. Myosin-V was detected in intact synaptosomes and in lysed synaptosomes associated with a particulate fration. Our data suggest a role for brain myosin-V in membrane-cytoskeleton function in the synaptic region