Acupuncture combined with cinesiotherapy cupping for knee osteoarthritis with stagnation and blood stasis syndrome: a randomized controlled trial / 中国针灸

OBJECTIVE@#To compare the clinical efficacy between acupuncture combined with cinesiotherapy cupping and acupuncture combined with conventional cupping for knee osteoarthritis (KOA) with stagnation and blood stasis syndrome, and to seek a better solution for KOA.@*METHODS@#A total of 78 patients of KOA with stagnation and blood stasis syndrome were randomly divided into an observation group and a control group, 39 cases in each group (3 cases in the observation group and 2 cases in the control group lost contact). Both groups were treated with acupuncture at Neixiyan (EX-LE 4), Dubi (ST 35), Xuehai (SP 10), Liangqiu (ST 34), Heding (EX-LE 2), Zusanli (ST 36), Yinlingquan (SP 9), Yanglingquan (GB 34) and Xuanzhong (GB 39). Based on the acupuncture treatment, the control group was treated with conventional cupping. The No. 4 cupping glass was used for Xuehai (SP 10), Liangqiu (ST 34) and Fengshi (GB 31), while the No. 3 cupping glass was used for Yinlingquan (SP 9), while the cupping with appropriate size was used for points; the cupping glass was retained for 5 min. Based on the acupuncture treatment, the observation group was treated with cinesiotherapy cupping. The selection of acupoint and cupping glass was identical as the control group. The patients were instructed to perform knee flexion-extension, hip abduction-adduction, weight-bearing and other active exercise while cupping; the treatment was given once a day, 10 times as a course of treatment; totally three courses were given with an interval of 2 days between the courses. The patient's symptom scores, pain scores and knee function scores were recorded before and after treatment. The amount of joint effusion was measured by ultrasound; the level of interleukin-1 (IL-1), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) in joint effusion were measured by ELISA.@*RESULTS@#After treatment, the total effective rate in the observation group was 94.4% (34/36), which was significantly higher than 86.5% (32/37) in the control group (0.05).@*CONCLUSION@#The acupuncture combined with cinesiotherapy cupping could alleviate pain, improve joint function and reduce joint effusion, which is superior to acupuncture combined with conventional cupping.

Studies on chemical constituents of Dioscorea opposita / 中国中药杂志

<p><b>OBJECTIVE</b>To study the chemical constituents of Dioscorea opposita.</p><p><b>METHOD</b>The chemical constituents were isolated and purified by silica gel column chromatography, and the structures were elucidated by their spectroscopic data and physico-chemical properties.</p><p><b>RESULT</b>Twelve compounds were obtained and identified as palmitic acid (1), beta-sitosterol (2), oleic acid (3), beta-sitosterol acetate (4), 5-(hydroxymethyl)furfural (5), nonanedioic acid (6), beta-daucosterol (7), cyclo-(Phe-Tyr) (8), cyclo-(Tyr-Tyr) (9), 6-methyl citrate (10), 1, 5-dimethyl citrate (11), trimethyl citrate (12).</p><p><b>CONCLUSION</b>Compounds 3-12 were isolated from this plant for the first time and cyclodipeptides were firstly isolated from the Dioscoreae family; Compound 9 was a new natural product.</p>

Composition and property characterization of Rhizoma Dioscoreae polysaccharide-Fe (III) complex / 中国中药杂志

<p><b>OBJECTIVE</b>To characterize properties of Rhizoma Dioscoreae polysaccharide-Fe (III) complex (RDPC) and analyze its composition.</p><p><b>METHOD</b>Physicochemical properties, such as character, solubility and stability of RDPC were studied. Surface structure of RDPC was studied by Infrared spectroscopic technique and transmission electron microscopy. The content of Fe (III) in RDPC was determined by o-phenanthroline spectrophotometry after being treated by ashing, wet digestion, or direct dissolution methods. Content of polysaccharide in RDPC was determined by sulphuric acid-phenol method.</p><p><b>RESULT</b>RDPC was brownish red powder. It could dissolve in water, its aqueous solution was very stable at the pH from 3.8 to 11.6. RDPC was a surface complex in which polysaccharide combined with beta-FeOOH as core. The content of Fe (III) in RDPC was 17.05%, 16.53%, 17.10% respectively after being treated by 3 different pretreatment methods. Content of polysaccharide in RDPC was 16.27%.</p><p><b>CONCLUSION</b>This is the first report of RDPC which was stable under physiological pH conditions and could be a new candidate for iron-supplementary.</p>

Statistical analysis of residues of heavy metals in Chinese crude drugs / 中国中药杂志

<p><b>OBJECTIVE</b>To analyze the residues of heavy metals in Chinese crude drugs.</p><p><b>METHOD</b>The SPSS 13.0 software was used to analyze the data of Cu, Pb, As, Cd, Hg collected in literatures. And, Green Trade Standards of Importing & Exporting Medicinal Plants & Preparations was used as the standard to evaluate the pollution condition of Cu, Pb, As, Cd, Hg in Chinese crude drugs.</p><p><b>RESULT</b>Chinese crude drugs were contaminated by heavy metals in different levels. The content of Cu, Pb, As, Cd, Hg exceeded the limit of the standard and the percentage was 21.0%, 12.0%, 9.7%, 28.5%, 6.9%, respectively; the phenomena of two, three and four metals exceeding limited standard simultaneity in a drug were also found and the percentage was 4.6%, 1.5%, 0.7%, respectively; the content of heavy metals in Radix Platycodi, Radix Asari and Rhizoma Coptidis was higher among the thirty-six Chinese crude drugs; All of the content of five heavy metals in Barbary Fructus Lycii Rhizoma Anemones Raddeanae, Radix Panacis Quiquefolii and Fructus Aurantii were below the limit; The pollution levels of heavy metals in different locality were different; The content of Cu, Pb in cultivated Chinese crude drugs was higher than that in wild Chinese crude drugs, while the content of As in wild Chinese crude drugs was higher than that in cultivated Chinese crude drugs.</p><p><b>CONCLUSION</b>The pollution levels of heavy metals in Chinese crude drugs were detailed reported in this paper. And it provided ways for the further study of heavy metals in Chinese crude drugs.</p>

Studies on chemical constituents of Acroptilon repens / 中国中药杂志

<p><b>OBJECTIVE</b>To investigate the chemical constituents of Acroptilon repens.</p><p><b>METHOD</b>The ethanol extract of A. repens was isolated and purified by means of chromatography. These compounds were identified by their spectral data.</p><p><b>RESULT</b>11 compounds were isolated and identified as 2alpha, 9beta-dihydroxy-dehydrocostus lactone (1) , cynaropicrin (2) , apigenin (3) , stigmasterol (4) , 4' -hydroxywogonin (5) , ethyl caffeate (6) , p-methoxy-cinnamic acid (7) , luteolin (8) , daucosterol (9) , apigenin-7-O-beta-D-glucoside (10) , syringin (11).</p><p><b>CONCLUSION</b>Compounds 5-11 were isolated from A. repens for the first time. Compound 1 is new compounds.</p>

Studies on flavonoid constituents from herbs of Artemisia ordosica II / 中国中药杂志

<p><b>OBJECTIVE</b>To study the chemical constituents of herbs of Artemisia ordosica.</p><p><b>METHOD</b>The chemical constituents were isolated and repeatedly purified on silica gel column and the structures were elucidated by the NMR spectra and physicochemical properties.</p><p><b>RESULT</b>Eight flavones were obtained and they were identified as isosakuranetin, 7, 4'-dimethylaro madendrin, acacetin, cirsimaritin, rhamnetin, eupatolin, 5, 7, 2', 4'-tetrahydroxy-6, 5'-dimethoxyflavone, hyperoside.</p><p><b>CONCLUSION</b>All the compounds were obtained from herbs of A. ordosica for the first time.</p>