RESUMO
Background: The incidence of inflammatory bowel disease is increasing in the pediatric population worldwide. Need and purpose of review: There is paucity of high quality scientific data regarding pediatric inflammatory bowel disease. Most of the guidelines are offshoots of work done in adults, which have been adapted over time to diagnose and treat pediatric patients. This is in part related to the small numbers in pediatric inflammatory bowel disease and less extensive collaboration for multicentric trials both nationally and internationally. Methods: A literature search was performed using electronic databases i.e. Pubmed and OVID, using keywords: pediatric, inflammatory bowel disease, Crohn’s disease, Ulcerative colitis, epidemiology and guidelines. This article amalgamates the broad principles of diagnosing and managing a child with suspected inflammatory bowel disease. Main conclusions: 25% of the patients with inflammatory bowel disease are children and and young adolescents. The primary concern is its impact on growth velocity, puberty and quality of life, including psychosocial issues. Treatment guidelines are being re-defined as the drug armamentarium is increasing. The emphasis will be to achieve mucosal healing and normal growth velocity with minimal drug toxicity.
RESUMO
Inflammatory pseudotumor is an uncommon tumor with a variable natural course. We report a case of omental pseudotumor in a 6-year-old male child. The child's clinical presentation was suggestive of an omental mass, which was operated upon after investigations. Histopathology revealed it to be an inflammatory pseudotumor. The case is presented for its unusual location.
RESUMO
To determine the accuracy of references published in Indian Pediatrics, we reviewed the reference lists appended to the original articles published in Indian Pediatrics during the year 2002 (volume 39) for citation and quotation accuracy. A total of 176 references out of 322 cited in 17 original articles could be retrieved from available resources. Errors of citation were found in 69 (39.27 percent) references while errors of quotation were found in 15 (8.6 percent) references. The most common errors were those in the name of authors and title of the article. Contributors should make serious efforts to check the accuracy of the references cited in their manuscripts.
Assuntos
Bibliografias como Assunto , Índia , Pediatria , Publicações Periódicas como Assunto/estatística & dados numéricosRESUMO
Germ cell tumours in liver are uncommon. Fewer than 20 cases have been reported in the literature. Primary mixed malignant germ cell tumours of liver are even rare. Here we describe a case of primary mixed malignant germ cell tumour of left lobe of liver in a two and half year old male boy. This is the first reported case of primary mixed malignant germ cell tumour with components of yolk sac tumour and mature teratoma in an infant. The patient complained of gradual increase in abdominal distension, upper abdominal pain and loss of weight. Ultrasonography and computed tomography of the abdomen revealed a large hepatic mass. Serum alpha-feto protein levels were raised. Left lobectomy of liver was done and chemotherapy was initiated. Histopathology of specimen disclosed yolk sac tumour and mature teratoma. Levels of serum alpha-feto protein declined rapidly. Widespread intrahepatic metastasis developed and patient died due to liver dysfunction after six months of left lobectomy.