RESUMO
Farsi and English are both Indo-European languages with similarities in their roots
As such, this experiment was conducted to understand which English accent [i.e. American, British or Australian accents] would be easier for Iranians to adapt. To answer this question, 30 medical students performed three different activities of [I] listening to audio texts in three accents, [II] taking part in an oral interview and [III] completing an attitude questionnaire. The activities examined comprehensibility of the accents the participants were subjected to, type of accent they themselves produced and their attitude toward the accents under study
As for the audio texts, the order of presenting the three accents to the subjects was counterbalanced in order to control the order effect. The data on audio materials were analyzed for comprehensibility, accentedness, intelligibility and acceptability. Regarding comprehensibility, American accent was the most comprehensible [85%]
Considering accentedness, intelligibility and acceptability, the participants found American accent the least accented [70%], the most intelligible 80% and the most acceptable [95%]
In the interviews, students' accents were closer to the American accent. 85 percent of the participants used American accent in their conversational exchanges. Those with British and Australian accents formed 10% and 5% respectively. Regarding attitude, also, the participants mostly [90%] preferred American accent over the British or Australian accents. Students' tendency to adapt American accent more openly is mainly rooted in a mentality that American accent is easiest for the brain to digest
RESUMO
The approach and novelty of this scientific work was to formulate the appropriate Streptozotocin (STZ) and Alloxan dosage in different routes of administration to imply minimum mortality rate and high incidence of diabetes mellitus (DM) in the rat experiment model. Rats were randomly divided into STZ, Alloxan and control groups. 1-Alloxan group was divided into two subgroups: intraperitoneal (ip) subgroups which received a single dose of, 140, 120, 100 and 80 mg/kg; and the subcutaneous (sc) subgroups which received a single dose of, 120, 110, 100, 90, and 80 mg/kg. 2-STZ group was divided into four subgroups of ip route. The ip subgroup which received intraperitoneally a single dose of, 30, 35, 40 and 50 mg/kg. 3-The control group: This group received solo distilled water. The injection day was considered as the day zero. Blood glucose levels and mortality rate were recorded. Subsequently, 30 days after, the logistic regression modeling was used to evaluate the effect of the explanatory variables, the dose levels, and route approaches, on the probability of DM incidence, and mortality. According to the statistical logistic analysis for Alloxan, it is concluded that the minimum dosage needed to induce DM was 120 mg/kg by sc method (probability 0.712). In addition, the logistic analysis for STZ showed that the optimal dose-level for STZ was 40 mg/kg with ip with approximate induction of DM probability 0.764. Based on the data, male Wistar rats in which received a single dosage of Alloxan by sc injection at dose of 120 mg/kg showed the most desirable result of induction of type I DM; furthermore, those in which received STZ by ip injection at the dose of 40 mg/kg developed a persistent and optimal DM state characterized by high rate of DM induction and low- level of mortality.