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Background: The batting performance is assessed by considering the batting average and strike rate of a batsman. With the induction of T-20 cricket matches, the strike rate of a batsman has gained much attention from coaches and team management. To increase the strike rate a batsman required to hit powerful shots for boundaries, which assist in making maximum scores at the minimum ball. Therefore, this investigation was planned to determine the effect of body size on the batting performance of cricket batsman. Methods: the literature for this study was selected for cricket coaching manual, cricket books, cricket batting videos, a biography of cricket batsmen, research articles. The academic documents were downloaded and shortlisted from Google Scholar, Research Gate, EBSCO, and ProQuest from 1990 to 2019. Results: The synthesized literature review concludes, stature, longer legs, longer arms, and lean body mass of a batsman show positive effects on the execution of powerful shots in cricket. Furthermore, the maximum strength of muscles assists a batsman to boost up the initial velocity of bat swing to accomplish the ball speed for a successful and powerful shot. Conclusions: Although stature and longer limbs of batsmen are associated with batting performance. On the other hand, the specific training would also enhance the capacity of cricket batsman for powerful shots in cricket. A future study was proposed to investigate the effect of training on the batting performance.
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Abstract The bacterial species employ various types of molecular communication systems recognized as quorum sensing for the synchronization of differential gene expression to regulate virulence traits and biofilm formation. A variety of quorum sensing inhibitors; molecules that interfere with quorum sensing among bacteria have been examined which can block the action of autoinducers. Moreover, the studies have scrutinized various enzymes for their quorum quenching activity resulting in the degradation of signaling molecules or blocking of gene expression. So far, the studies have found that these approaches are not only capable to reduce the pathogenicity and biofilm formation but also resulted in increased bacterial susceptibility to antibiotics and bacteriophages. The effectiveness of these strategies has been validated in different animal models and it seems that these practices will be transformed in near future to develop the medical devices including catheters, implants, and dressings for the prevention of bacterial infections. Although many of these approaches are still in the research stage, the increasing library of quorum quenching molecules and enzymes will open innovative perspectives for the development of antibacterial approaches which will extend the therapeutic arsenal against the pathogenic bacterial species.
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Animais , Camundongos , Coelhos , Infecções Bacterianas/metabolismo , Biofilmes/efeitos dos fármacos , Percepção de Quorum/efeitos dos fármacos , Antibacterianos/farmacologia , Caenorhabditis elegans/microbiologia , Modelos AnimaisRESUMO
Abstract Flatulence and fullness of stomach is one of the most common problem associated with chickpea primary due to presence of some oligosaccharides and phenols. In this investigation Desi and Kabuli varieties were compared for these oligosaccharides and phenolic compounds. Furthermore, the effect of different processing and cooking methods such as soaking, cooking and germination in the reduction of these antiphysiological factors were are also studies. Maximum tannic acid (0.90 ± 0.20%) was observed in Parbat and C-44 while minimum (0.60 ± 0.04%) in Karak-2. Stachyose contents ranged between 1.10 ± 0.05 (Karak-3) to 1.42 ± 0.02% (Parbat) while raffinose was 0.63 ± 0.05(Karak-3) to 0.81 ± 0.02% (Dasht). The highest tannic acid content was reduced up to 50% in C-44 by cooking of 72 hours germinated seeds. Stachyose and raffinose contents were completely removed after 72 hours germination. Present studies revealed that cooking after germination is the most effective method to reduce the anti-nutritional factors of chickpea. Individually, soaking and cooking also contributed to the loss of the same factors but to a lesser extent.
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Objective:To study the screening of essential oils of Skimmia laureola leaves (SLO) for acute toxicity, antinociceptive, antipyretic and anticonvulsant activities in various animal models. Methods: SLO were extracted using modified Clevenger type apparatus. Acute toxicity test was used in mice to observe its safety level. Antinociceptive activity of SLO was evaluated in acetic acid induced writhing and hot plate tests. Yeast induced hyperthermic mice and pentylenetetrazole induced convulsive mice were used for the assessment of its antipyretic and anticonvulsant profile respectively. Results: Substantial safety was observed for SLO in acute toxicity test. SLO showed a high significant activity in acetic acid induced writhing test in a dose dependent manner with maximum pain attenuation of 68.48%at 200 mg/kg i.p. However, it did not produce any relief in thermal induced pain at test doses. When challenged against pyrexia evoked by yeast, SLO manifested marked amelioration in hyperthermic mice, dose dependently. Maximum anti-hyperthermic activity (75%) was observed at 200 mg/kg i.p. after 4 h of drug administration. Nevertheless, SLO had no effect on seizures control and mortality caused by pentylenetetrazole. Conclusions:In vivo studies of SLO showed prominent antinociceptive and antipyretic activities with ample safety profile and thus provided pharmacological base for the traditional uses of the plant in various painful conditions and pyrexia. Additional detail studies are required to ascertain its clinical application.
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One of the objectives of the National drug policy is to promote the rational use of drugs by prescribers, dispensers and consumer. However, in developing countries, inappropriate prescribing has been identified among health facilities. Analgesics have been identified as one of the commonly prescribed drugs among prescribers in managing pain. Therefore, the objective of this study is to assess the analgesic usage among physicians at the outpatient department of a tertiary health facility. This study was a descriptive cross sectional survey. A total of 624 prescription sheets containing prescribed analgesics was obtained and examined. Data generated were analysed using SPSS version 15 software. The mean number of analgesics per prescription was 1.23 ± 0.49. The mean number of drug per prescription was 3.68 ± 1.54. A total of 16 analgesics were prescribed and the most prescribed analgesic was Paracetamol. There were low irrational analgesics combinations among prescribers. Most of the analgesics were prescribed correctly. Majority of the analgesics were prescribed in generic names. Oral dosage form formed the bulk of the prescribed analgesics. Also, most of the analgesics were from the Essential Drug List and almost all analgesics prescribed were available in the Pharmacy department for dispensing to patients as at the time the prescriptions were written. This study revealed that pain management in the centre was largely in accordance to the National Drug Policy and Standard treatment guidelines.
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The objective of this work was the phylogenetic characterization of local clinical isolates of uropathogenic E. coli with respect to drug resistance. A total of 59 uropathogenic E. coli responsible for community acquired urinary tract infections were included in this study. A triplex PCR was employed to segregate each isolate into four different phylogenetic groups (A, B1, B2 and D). Drug resistance was evaluated by disc diffusion method. The drugs used were ampicillin, aztreonam, cefixime, cefoperazone, ceftriaxone, cephradine among â-lactam group; amikacin, gentamicin, and streptomycin among aminoglycosides; nalidixic acid and ciprofloxacin from quinolones; trimethoprim-sulfomethoxazole, and tetracycline. Among 59 uropathogenic E. coli isolates majority belonged to phylogenetic group B2 (50 percent) where as 19 percent each belonged to groups A and B1, and 12 percent to group D. All the isolates were multiple drug resistant (MDR). Most effective drugs against Group A, B1, and B2 were gentamicin, amikacin and cefixime; ceftriaxone and quinolones; and ceftriaxone and amikacin, respectively. Group D isolates were found to be highly resistant to all drugs. Our results have shown emergence of MDR isolates among uropathogenic E. coli with dominance of phylogenetic group B2. However, it was found that group D isolates were though less frequent, more drug resistant as compared with group B2. Groups A and B1 were relatively uncommon. Amikacin, ceftriaxone and gentamicin were the most effective drugs in general.
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Humanos , Escherichia coli/isolamento & purificação , Escherichia coli/patogenicidade , Técnicas In Vitro , Filogenia , Pacientes AmbulatoriaisRESUMO
Increasing scarcity of irrigation water is a major threat to sustainable production of cotton (Gossypium hirsutum L.). Identifying genomic regions contributing to abiotic stress tolerance will help develop cotton cultivars suitable for water-limited regions through molecular marker-assisted breeding. A molecular mapping F2 population was derived from an intraspecific cross of the drought sensitive G. hirsutum cv. FH-901 and drought tolerant G. hirsutum cv. RH-510. Field data were recorded on physiological traits (osmotic potential and osmotic adjustment); yield and its component traits (seedcotton yield, number of bolls/plant and boll weight); and plant architecture traits (plant height and number of nodes per plant) for F2, F2:3 and F2:4 generations under well-watered versus water-limited growth conditions. The two parents were surveyed for polymorphism using 6500 SSR primer pairs. Joinmap3.0 software was used to construct linkage map with 64 polymorphic markers and it resulted into 35 markers mapped on 12 linkage groups. QTL analysis was performed by composite interval mapping (CIM) using QTL Cartographer2.5 software. In total, 7 QTLs (osmotic potential 2, osmotic adjustment 1, seedcotton yield 1, number of bolls/plant 1, boll weight 1 and plant height 1) were identified. There were three QTLs (qtlOP-2, qtlOA-1, and qtlPH-1) detected only in water-limited conditions. Two QTLs (qtlSC-1 and qtlBW-1) were detected for relative values. Two QTLs (qtlOP-1 and qtlBN-1) were detected for well-watered treatment. Significant QTLs detected in this study can be employed in MAS for molecular breeding programs aiming at developing drought tolerant cotton cultivars.