1.
Artigo
em Inglês
| IMSEAR
| ID: sea-21298
RESUMO
The mutagenic potential of phenytoin (PHT) was studied using the sister chromatid exchange (SCE) assay. Twenty nine PHT treated epileptics, 32 untreated and 32 normal healthy controls were analysed. Similar SCE frequencies were observed in untreated patients and patients on PHT monotherapy. Both groups had significantly increased SCE frequency as compared to controls. No positive correlation of SCE frequency with sex and duration of therapy was observed. The results of the present study suggest the role of the disease condition in inducing genetic damage as assessed by increased SCE frequencies.
Assuntos
Adolescente , Adulto , Epilepsia/tratamento farmacológico , Feminino , Humanos , Masculino , Testes de Mutagenicidade , Fenitoína/efeitos adversos , Troca de Cromátide Irmã/efeitos dos fármacos
2.
J Indian Med Assoc
; 1983 Dec; 81(11-12): 208-9
Artigo
em Inglês
| IMSEAR
| ID: sea-102616
Assuntos
Humanos , Cálices Renais , Nefropatias , Pelve Renal , Masculino , Pessoa de Meia-Idade , Ruptura Espontânea
3.
J Indian Med Assoc
; 1983 Jul 1-16; 81(1-2): 15-6
Artigo
em Inglês
| IMSEAR
| ID: sea-96168
Assuntos
Adulto , Humanos , Malacoplasia/patologia , Masculino , Doenças da Bexiga Urinária/patologia
4.
J Indian Med Assoc
; 1980 Oct; 75(8): 166-7
Artigo
em Inglês
| IMSEAR
| ID: sea-96532