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Indian J Exp Biol ; 2006 Mar; 44(3): 246-9
Artigo em Inglês | IMSEAR | ID: sea-59069

RESUMO

In the present study, the root extract of Rhus oxyacantha contained 25.33 mg of catechin equivalent per mg of fresh wt and was found rich in proanthocyanidins compared to vine shoot, grape pips and leaves. The chromatographic analysis of the extract suggested the presence of (+) catechin, (-) epicatechin -3-O-gallate as well as proanthocyanidinic oligomers and polymers. Root cortex inhibited the ascorbic acid oxidation by dioxygen. It also prevented DDT-induced thymocytes death in a dose-dependent manner. The results suggested antioxidant property of root extract of Rhus oxyacantha which could be ascribed to its free radical scavenging nature.


Assuntos
Animais , Antioxidantes/metabolismo , Ácido Ascórbico/farmacologia , Sobrevivência Celular/efeitos dos fármacos , Células Cultivadas , Masculino , Oxirredução/efeitos dos fármacos , Extratos Vegetais/metabolismo , Raízes de Plantas/química , Proantocianidinas/química , Ratos , Ratos Wistar , Rhus/química , Timo/citologia
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