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OBJECTIVE@#To study the significance of the level of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) in serum and bronchoalveolar lavage fluid (BALF), Acute Physiology and Chronic Health Evaluation II (APACHE II) score, and Sequential Organ Failure Assessment (SOFA) score in evaluating the conditions and prognosis of children with severe pneumonia.@*METHODS@#A total of 76 children with severe pneumonia who were admitted from August 2017 to October 2019 were enrolled as the severe pneumonia group. According to the treatment outcome, they were divided into a non-response group with 34 children and a response group with 42 children. Ninety-four children with common pneumonia who were admitted during the same period of time were enrolled as the common pneumonia group. One hundred healthy children who underwent physical examination in the outpatient service during the same period of time were enrolled as the control group. The serum level of sTREM-1, APACHE II score, and SOFA score were measured for each group, and the level of sTREM-1 in BALF was measured for children with severe pneumonia. The correlation of the above indices with the severity and prognosis of severe pneumonia in children was analyzed.@*RESULTS@#The severe pneumonia group had significantly higher serum sTREM-1 level, APACHEII score, and SOFA score than the common pneumonia group and the control group (P0.05).@*CONCLUSIONS@#The level of sTREM-1 in serum and BALF and SOFA score can be used to evaluate the severity and prognosis of severe pneumonia in children.
Assuntos
Criança , Humanos , APACHE , Líquido da Lavagem Broncoalveolar , Escores de Disfunção Orgânica , Pneumonia , Prognóstico , Curva ROC , Sepse , Receptor Gatilho 1 Expresso em Células MieloidesRESUMO
In recent years，hepatotoxicity problem of Polygonum multiflorum has caused high attention. Domestic scholars also explored the causes of liver damage caused by it. For example, the establishment of guideline for diagnosis and treatment of herb-induced liver injury, and the theory about relationship between hepatocyte toxicity and chemical composition, solvents, processing, use and pathological basis of patients and so on. To try to combine theory with practice，author analyzed risk factors about the case reports of P. multiflorum causing liver damage, and made some suggestions on P. multiflorum about individualized application, drug selection and requirements for taking. This for providing reference for the safe use of P. multiflorum.
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Objective To compare the operative precision between pioneer drilling guiding and full navigation guiding plates in the flapless immediate implantation. Methods Data of 50 immediate implants, which were implanted from 47 outpatients (50 implants) of Tianjin Stomatological Hospital from 2014 to 2016 were retrospectively analyzed. The patients were conducted on the pioneer drilling guiding system (22 implants) and full navigation guiding sytem (28 implants). The cone beam CT (CBCT) was preliminarily taken and modeled for each patient. All of the patients underwent implant surgery after making guiding plates by three-dimensional reconstruction, simulation planting design and the application of digital rapid prototyping technology. Cavity preparations were made by pioneer drilling and full navigation assisted with planting drills respectively to finish implantation. The post-operative CBCT was taken and performed the three-dimensional reconstruction. The implantation precision guiding by two systems were compared. Results All of the 50 immediate implants were successfully completed with the guiding plates. Implant mucositis appeared in one case after 3 months of temporary repair, and after the targeted therapy, the final repair was finished. The rest cases were finally completed. No implant was loose or fell off. The deviation was less in neck apex and root apex angle in full navigation group than that of pioneer drilling guiding group (P<0.01). But there was no significant difference in axial angle between the two groups after navigation and implantation (P>0.05). Conclusion The digital surgical guiding plates provide nice technical support for the application of the flapless immediate implantation. And the full navigation system has higher precision than that of the pioneer drilling navigation system.
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Objective To compare the operative precision between pioneer drilling guiding and full navigation guiding plates in the flapless immediate implantation. Methods Data of 50 immediate implants, which were implanted from 47 outpatients (50 implants) of Tianjin Stomatological Hospital from 2014 to 2016 were retrospectively analyzed. The patients were conducted on the pioneer drilling guiding system (22 implants) and full navigation guiding sytem (28 implants). The cone beam CT (CBCT) was preliminarily taken and modeled for each patient. All of the patients underwent implant surgery after making guiding plates by three-dimensional reconstruction, simulation planting design and the application of digital rapid prototyping technology. Cavity preparations were made by pioneer drilling and full navigation assisted with planting drills respectively to finish implantation. The post-operative CBCT was taken and performed the three-dimensional reconstruction. The implantation precision guiding by two systems were compared. Results All of the 50 immediate implants were successfully completed with the guiding plates. Implant mucositis appeared in one case after 3 months of temporary repair, and after the targeted therapy, the final repair was finished. The rest cases were finally completed. No implant was loose or fell off. The deviation was less in neck apex and root apex angle in full navigation group than that of pioneer drilling guiding group (P<0.01). But there was no significant difference in axial angle between the two groups after navigation and implantation (P>0.05). Conclusion The digital surgical guiding plates provide nice technical support for the application of the flapless immediate implantation. And the full navigation system has higher precision than that of the pioneer drilling navigation system.
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In China, many surveys have shown that most people do not have a correct understanding about cold and administration of anti-cold Chinese patent medicine preparations. The author conducted a systematic summary and analysis on the actual application of anti-cold Chinese patent medicine preparations as well as the warning on safe application of anti-cold Chinese patent medicine preparations in Clinical Medication Information of China Pharmacopoeia, in the expectation of reducing the blind application of anti-cold Chinese patent medicine preparations and providing traditional Chinese medicine pharmacists new ideas in monitoring the safe application of exterior syndrome-relieving Chinese patent medicine preparations.