Correlation between intraocular pressure and the biometric structure of the anterior chamber in patients of chronic renal failure with hemodialysis / 国际眼科杂志(Guoji Yanke Zazhi)

@#AIM: To investigate the correlation between intraocular pressure(IOP)changes pre- and post-hemodialysis(HD)and the biometric structure of the anterior chamber in patients of chronic renal failure. <p>METHODS: Fifty-two patients(take right eye as study one)with hemodialysis that were diagnosed with chronic renal failure by nephrology in our hospital from January 2015 to December 2015 were collected. Fifty-two eyes were divided into four groups based on Shaffer classification combined with ultrasound biomicroscopy(UBM)and gonioscopy manifestations: wide angle group, narrow angle group, extremely narrow group and close angle group. Venous blood was collected to get plasma colloid osmotic pressure before HD and within 60s after HD. IOP was measured with rebound intraocular pressure gauge in a supine positon approximately 30min before starting HD, 2h after HD begin and approximately 30min after HD ending. Approximately 30min before and after HD, central corneal thickness was measured with corneal endothelial cell counter, central anterior chamber depth and lens thickness were taken by A scan, angle opening distance, trabecular iris angle, iris thickness and ciliary body thickness were measured by UBM. <p>RESULTS: Plasma osmotic pressure reduced after HD, the difference was statistically significant(<i>t</i>=3.04, <i>P</i><0.05). The means of IOPs among three measurement points were not all the same(<i>F</i>=41.69, <i>P</i><0.01). The IOP in 2h after HD had significant difference compared with before HD(<i>P</i><0.01).The IOP in 30min after HD ending had significant difference compared with 2h after HD(<i>P</i><0.01). The means of IOPs among three groups were not all the same(<i>F</i>=6.44, <i>P</i><0.01). The IOP in extremely narrow angle group had significant difference compared with that in wide angle group and narrow angle group(<i>P</i><0.05). Ciliary body thickness decreased after HD in every group, while only in wide angle group showed significant change after ending HD(<i>t</i>=2.61, <i>P</i><0.05). Central corneal thickness, central anterior chamber depth, angle opening distance, trabecular iris angle and iris thickness decreased, while lens thickness increased after HD. But all these changes between before HD and after HD in every group had no significant difference. <p>CONCLUSION: The influence of hemodialysis on IOP is related to the biometric structure of the anterior chamber. And extremely narrow angle is risk factor of elevated IOP during hemodialysis, narrow angle may be a risk factor. While patients with wide angle is relatively safe. We suggest to take ocular examination as early as possible for patients with hemodialysis, and focus on patients with narrow angle.

Clinical research on auricular point therapy for 1477 cases of biased constitution / 中国针灸

<p><b>OBJECTIVE</b>To observe the efficacy of biased constitution patients treated by auricular point therapy on the basis of "preventive treatment" theory.</p><p><b>METHODS</b>By means of self-control, 1477 cases of biased constitution were regulated by auricular point sticking therapy or acupuncture, and follow-up and statistical analysis were conducted to observe the efficacy.</p><p><b>RESULTS</b>There were 322 markedly effective patients, 914 effective patients, 241 failed patients and the total effective rate was 83.7% (1236/1477).</p><p><b>CONCLUSION</b>The comprehensive auricular treatment which is easy to operate and acceptable for patients has obvious effect in biased constitution patients. As a new direction of the "preventive treatment" theory, it can be promoted to be a new intervention way of health care.</p>

In vitro stability of Shuxuening with representative infusion solutions / 中国药学杂志

OBJECTIVE: Compatible stability of Shuxuening injection with 5 different infusions and glucose injection with insulin. METHODS: Taking Shuxuening injection with 5 different injections and glucose injection with insulin at room temperature, according to the clinical application of dose, study the compatible stability of solution with color, pH, particulates, contents of flavonoid compounds, total lactones, ginkgolides A, B and C. RESULTS: Compatibility of the solution within 12 h, the solution pH and color, compared with begin, showed no change; number of insoluble particles, ≥ 10 and 25 μm size were acceptable; flavonoid fingerprint did not change significantly; ginkgolide A, B, C and total lactone content did not change. CONCLUSION: Shuxuening injection was stable for up to 12 h in vitro in 5 different solutions and glucose injection with insulin at room temperature. Therefore, Shuxuening injection can be constituted, mixed with experiment infusion fluids. Copyright 2012 by the Chinese Pharmaceutical Association.