Effect of electrical stimulation on oxidative stress in tissues in a rat model with incision wound

Electrical stimulation (ES) are known to have beneficial effects in wound healing. However, the effect of electrical stimulation in wound theraphy on the oxidant and antioxidant levels of various tissues in the body remains unclear. Here, we investigated the effects of electrical stimulation on the oxidative stress capacity of tissues in a rat model with a surgical incision wound on the lateral line of the femoral region. Rats divided in two groups: control and ES group. A longitudinal skin incision was made only from the right lateral line of all rats. ES was applied 200 ?s, 20 Hz, 2mA for 20 min during 15 days. Some oxidative stress parameters (malondialdehyde (MDA), reduced glutathione (rGSH), glucose-6-phosphate dehydrogenase (G6PD), glutathione peroxidase (GPx) and catalase (CAT)) in tissues (brain, heart, kidney, liver, testis, gastrocnemius and quadriceps femoris muscle) were obtained spectrophotometrically. The ES reduced oxidative stress by decreasing MDA and simultaneously increasing different antioxidants in different tissues. The results suggest that incision wound could induce oxidative stress in tissues and electrical stimulation post-incision wound may have ameliorative effect.

Effect of physical activity in daily life on muscle weight and relative weight of the m. triceps surae / 体力科学

In this paper, effects of physical activity in daily life on m. triceps surae were considered comparing the cadavers with decubitus with those without decubitus on muscle weight and relative muscle weight. The muscles were dissected from 18 cadavers (13 males and 5 females) aged 36 to 90 which were preserved in a 10% formalin solution for about one year. Immediately after the removal, weights of gastrocnemius and soleus were measured.<BR>Mean values of the muscle weights of soleus, gastrocnemius and combined total were heavier in male than in female. Those of the relative weights of soleus were larger than those of gastrocnemius in both sexes. The muscle weights showed remarkable inter-individ-ual variations and sexual differences. The decubitus group (non-active group) showed lighter muscle weight than the normal group did in both sexes. However, there were no differences in the relative muscle weight between both groups in both sexes.<BR>The rate of lack of m. plantaris was 11.1%.<BR>From these results, it was suggested that the relative muscle weight might not be influenced by physical activity in daily life but the muscle weight might change consid-erably related to it.