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Antecedentes: el síndrome de ovario poliquístico (SOP) es una afección endocrina común que se presenta en las mujeres y se asocia con problemas como irregularidades menstruales; hirsutismo; obesidad; resistencia a la insulina; acné; y vida posterior con diabetes mellitus y cáncer de útero. El objetivo del estudio fue evaluar las características fenotípicas y los factores de riesgo del síndrome de ovario poliquístico en estudiantes de enfermería. Materiales y métodos: Estudio transversal (descriptivo) que incluyó una muestra de 400 mujeres de la Facultad de Enfermería de la Universidad de Zagazig, Egipto. Se utilizaron para la recopilación de datos; hoja de cuestionario de entrevista estructurada, datos relacionados con medidas antropométricas, factores de riesgo sobre el SOP y lista de verificación observacional sobre las características fenotípicas de la PCO. Resultados: el 6% de las alumnas estudiadas tenía antecedentes familiares de PCO, casi la mitad de ellas consumía comida rápida, más de la mitad de las alumnas estudiadas tenía hirsutismo, más de una cuarta parte tenía acné, (14,5%) tenía irregularidades menstruales y una tercera parte. de ellos tenían un aumento de peso anormal continuo. Además, este estudio mostró que se encontró falta de conciencia entre la mayoría de las niñas sobre el SOP. Discusión: Por tanto, se podría concluir que los antecedentes familiares de SOP, la obesidad y los hábitos alimentarios de comida rápida se encuentran como factores predisponentes para el desarrollo de SOP. El riesgo de síndrome de ovario poliquístico aumenta con la presencia de uno o más factores predisponentes identificados. La mayoría de los factores probados como factores predisponentes en nuestro estudio están interrelacionados entre sí y son en su mayoría modificables. Aunque el SOP es un trastorno endocrino prevalente, había un conocimiento deficiente entre las estudiantes de la Facultad de Enfermería de la Universidad de Zagazig. Conclusiones: El estudio recomendó un programa de detección del ministerio de salud para la detección temprana de los factores predisponentes del SOP, incluidos los estudiantes de secundaria y los estudiantes de facultades, a través de programas educativos y mensajes a través de la consejería, folletos, para aumentar la conciencia de los estudiantes sobre los síntomas del SOP. Investigar más sobre el tamaño de la muestra más grande para identificar cómo el problema es riesgoso y cómo abordarlo. Incluyendo el problema en redes sociales y canales saludables.
Background: Polycystic ovarian syndrome (PCOS) is a common endocrine condition that occurs in women and is associated with problems such as menstrual irregularities; hirsutism; obesity; insulin resistance; acne; and later life with diabetes mellitus and uterine cancer. The study aim was to assess phenotype characteristics and risk factors of polycystic ovarian syndrome among nursing students. Materials and Methods: Cross sectional study (descriptive) included a sample of 400 females from Faculty of Nursing, Zagazig University, Egypt. Were used for data collection; structured-interviewing questionnaire sheet, data related to anthropometric measures, risk factors about PCOS and observational check list about phenotype characteristics of PCO. Results: 6% of the studied student females had family history of PCO, nearly half of them had fast food, more than half of studied student females had hirsutism, more than one quarter had acne, (14.5%) had menstrual irregularity and one third of them had continuous abnormal weight gain. Also, this study showed that lack of awareness was found among majority of girls about PCOS. Discussion: Therefore, it could be concluded that, family history of PCOS, obesity and fast-food diet habits are found to be the predisposing factors for development of PCOS. The risk of PCOS increases with presence of one or more identified predisposing factors. Most of the factors tested as predisposing factors in our study are interlinked to each other and are mostly modifiable Although that PCOS is prevalent endocrine disorder, there was poor knowledge among student females in Faculty of Nursing Zagazig University. Conclusion: The study recommended screening program from ministry of health for early detection of predisposing factors of PCOS including the secondary school students and faculties students through educational programs and messages through the counseling, brochures, to increase students' awareness about PCOS symptoms. Further research on larger sample size to identify how the problem is risky and how to deal it. Including the problem in social media and healthy channels
Тема - темы
Humans , Female , Adolescent , Adult , Middle Aged , Phenotype , Preventive Health Services , Students, Nursing/statistics & numerical data , Health Knowledge, Attitudes, Practice , Interviews as Topic/statistics & numerical data , Risk Factors , Health Surveys/statistics & numerical data , Early Diagnosis , Educational and Promotional Materials , Feeding Behavior , Medical History Taking , Menstruation DisturbancesРеферат
A high-fat diet can cause obesity and type 2 diabetes mellitus. This study aimed to observe the antioxidant compounds ofCordyline terminalis’s leaf extract which have the ability to be in vitro antioxidant and antidiabetic. Phytochemical tests andIC 50 to dpph were carried out in vitro. The study was conducted in vivo using 24 female wistar rats, which were dividedinto 4 groups: control of normal rats, high fat diet in obese rats, extract 100 mg / kg bw and extract 200 mg / kg bw. After30 days of research, blood samples were taken for examination of triglycerides, glucose, and free fatty acids. The resultsshowed that methanol extract contained saponins, steroids, flavonoids, alkaloids and polyphenols. The methanol extract canreduce free radicals with IC50 88.25 ppm. In vivo test results showed that there was a significant differences (p <0.05) in thelevels of TG, glucose and free fatty acids with the treatment of methanol extract (100 mg / kg bw and 200 mg / kg bw)compared to the high fat group. Based on the results of the study, it can be concluded that the methanol extract of andongleaves contained antioxidant compounds that act as antidiabetic in obese wistar rats.