A Case of Tick bite Caused by Ixodes monospinosus / 대한피부과학회지

The occurrence of tick bites and related dermatoses have been rarely described in Korea. Ticks may cause various infectious diseases associated with dermatoses by transmission of the mediating pathogens such as virus, bacteria and rickettsia. We describe herein, to our knowledge, the first tick bite with Ixodes monospinosus in Korea, The patient, a 64-year old male, was bitten by a tick while climbing a mountain which is located in the Kanghwado. He had an asymptomatic, yellowish pea-sized tick attached on the right antecubital area for 7 days' duration, which was identified as an adult female of I. monospinosus by the scanning electron microscopic examination.

An Immunohistochemical Studcy of Estrogen-receptors and Progesterone-receptors Expression in Pyogenic Granuloma / 대한피부과학회지

BACKGROUND: Pyogenic granuloma(PG) is a common lesion of the skin and mucous membranes. The gingival lesion developed during pregnancy termed epulis gravidarum is identical to PG. Many articles have appeared in the literature pertaining to this lesion and its putative relationship to the hormonal changes of pregnancy. Several clinical features such as association with oral contraceptive use and regression after delivery, suggest that PG may be a hormone-sensitive lesion. OBJECTIVE: Our aim was to determine whether estrogen or progesterone might affect the development of PG. METHODS: We performed immunohistochemical staining by using a monoclonal antibodies to estrogen receptor(ER) and progesterone receptor(PR) in 15 PG(pregnant women; 4 cases, non-pregnant women; 5 cases, and men; 6 cases). RESULTS: All 15 PGs were negative for ER. However, for PR, the degree of staining was different according to the patient group; pregnant women(3 cases[75%]: weak positive, 1 case[25%]: strong positive), non-pregnant women(3 cases[60%]: weak positive), and men(6 cases[100%]: negative). CONCLUSION: Our results suggest that estrogen or progesterone may not directly involve in the formation of these lesions. Further studies are needed to determine whether the other factors are related to the pathogenesis of PG.

A Case of Subcutaneous Infection with Trichosporon cutaneum in a Kidney Transplanted Patient / 대한의진균학회지

Tricosporon(T.) cutaneum is a member of the subfamily Trichosporideae in the family of Cryptococcaceae. It is now regarded as the same species as Trichosporon beigelii. It is widely distributed in soil, and is sometimes a part of the normal flora of the human skin, nail and mouth. It also may rarely colonize the throat and lower gastointestinal tract in hospitalized patients. T. cutaneum may cause white piedra in immunologically normal patients, a disease characterized by surface hard nodules along the hair shaft, however, skin infection by this organism is rare, T. cutaneum is referred to by Emmons as the agent of subcutaneous and systemic fungal infection. We report a case of subcutaneous infection with T. cutaneum in a kidney transplanted patient.

A Case of Umbilical Omphalomesenteric Duct Polyp / 대한피부과학회지

A umbilical omphalomesenteric duct polyp is the result of incomplete closure of the omphalomesenteric duct, which connects the midgut with the yolk sac of the embryo. It may be associated with underlying embryologic anomalies such as Meckels diverticulum and umbilical enteric fistula, the complications of which may at times be fatal. This rare malformation should be clinically discerned from persistent granulation tissue or pyogenic granuloma. Histologically, it shows a polypoid lesion consisting of ectopic gastrointestinal epithelium with the appearance of gastric, intestinal, or colonic mucosa. We report a case of an umbilical omphalomesenteric duct polyp in an 8-year-old male patient, who had had a bright-red polyp on the umbilicus from the age of 1 month and had not had any other types of underlying abnormalities.

Two Cases of Segmental Neurofibromatosis / 대한피부과학회지

Neurofibromatosis(NF) is a disorder characterized by its relative commonness, variability, and heterogeneity. It is usually expressed as a generalized form, but is rarely localized in a limited part of the body as a segmental form. In 1981, Riccardi classified NF into 8 types and a segmental form (type V) was defined by limitation of cafe-au-lait spots and/or neurofibroma on a given unilateral segment of the body. Recently we came across two cases of typical segmental neurofibromatosis. The First case was a 53-year-old woman with localized neurofibromatosis on the right T8,9 dermatome. The Second case was a 34-year-old man with localized neurofibromatosis on the right T5,6 dermatome. There were no cafe-au-lait spots, axillary frecklings, Lisch nodules or a family history in both cases. We report these rare cases with a literature review.

A Case of Inflammatory Metastatic Carcinoma of the Breast

A 51-year-old Korean woman presented with a non-tender, well-demarcated, reddish, edematous patch on the right anterior chest where a previous mastectomy and radiation therapy had been performed. She had been diagnosed as having infiltrating ductal carcinoma of the right breast about 1 year ago. Histopathological findings of the skin lesions were consistent with inflammatory metastatic carcinoma of the breast. Inflammatory carcinoma or carcinoma erysipeloides is a well-established entity most frequently associated with carcinoma of the breast. It is characterized by dermal lymphatic invasion by malignancy and clinically should be distinguished from erysipelas or cellulitis. We describe a case of inflammatory metastatic carcinoma derived from an infiltrating ductal carcinoma of the breast which can be clinically confused with radiation dermatitis.

Three Cases of Accessory Tragus / 대한피부과학회지

Accessory tragi are rare congenital malformations of the external ear. They are present from birth and appear as solitary or multiple papules located between the pretragal and sternoclavicular regions. Accessory tragi may be multiple but are almost always unilateral and rarely bilateral. We report two cases of bilateral accessory tragus and a typical case of unilat,eral accessory tragus manifesting as skin-colored papules on the preauricular area.