Knowledge, Compliance and Quality of Life of Mothers of Children with Atopic Dermatitis

PURPOSE: This study was conducted to survey knowledge, compliance, and quality of life of mothers who have children with atopic dermatitis, and to determine whether above mentioned factors influence each other. METHODS: The participants in this study were 165 mothers of children with atopic dermatitis recruited from one out-patient clinic in a hospital in Seoul. The data were collected between March 8, and April 16, 2010 using a structured questionnaire. RESULTS: The mean score for participants' knowledge was 4.17/5, for compliance, 4.27/5 and for quality of life, 3.42/5. Among the five domains of quality of life, emotional status had the lowest score (3.20/5). Knowledge was significantly correlated with compliance (r=.215, p<.005). However, quality of life was not correlated with knowledge (r=-.069) and compliance (r=-.077). CONCLUSION: Accurate knowledge affects compliance of mothers of children with atopic dermatitis. Therefore, to increase the level of compliance, it is necessary to enhance the knowledge of the mothers. Results also suggest that interventions are needed to improve poor quality of life, particularly the emotional condition of mothers of children with atopic dermatitis.

Gene expression pattern during osteogenic differentiation of human periodontal ligament cells in vitro

PURPOSE: Periodontal ligament (PDL) cell differentiation into osteoblasts is important in bone formation. Bone formation is a complex biological process and involves several tightly regulated gene expression patterns of bone-related proteins. The expression patterns of bone related proteins are regulated in a temporal manner both in vivo and in vitro. The aim of this study was to observe the gene expression profile in PDL cell proliferation, differentiation, and mineralization in vitro. METHODS: PDL cells were grown until confluence, which were then designated as day 0, and nodule formation was induced by the addition of 50 microg/mL ascorbic acid, 10 mM beta-glycerophosphate, and 100 nM dexamethasone to the medium. The dishes were stained with Alizarin Red S on days 1, 7, 14, and 21. Real-time polymerase chain reaction was performed for the detection of various genes on days 0, 1, 7, 14, and 21. RESULTS: On day 0 with a confluent monolayer, in the active proliferative stage, c-myc gene expression was observed at its maximal level. On day 7 with a multilayer, alkaline phosphatase, bone morphogenetic protein (BMP)-2, and BMP-4 gene expression had increased and this was followed by maximal expression of osteocalcin on day 14 with the initiation of nodule mineralization. In relationship to apoptosis, c-fos gene expression peaked on day 21 and was characterized by the post-mineralization stage. Here, various genes were regulated in a temporal manner during PDL fibroblast proliferation, extracellular matrix maturation, and mineralization. The gene expression pattern was similar. CONCLUSIONS: We can speculate that the gene expression pattern occurs during PDL cell proliferation, differentiation, and mineralization. On the basis of these results, it might be possible to understand the various factors that influence PDL cell proliferation, extracellular matrix maturation, and mineralization with regard to gene expression patterns.

Effects of Postpartum Depression and Temperament of Infant on Child-care Stress among Mothers of Newborn Infants

PURPOSE: This study was designed to identify mother and infant related factors that influence child-care stress among the mother of newborn infants. METHODS: Data were collected through self-administered questionnaires and descriptive statistics, correlation and multiple regression were used to analyze the data. The data survey was conducted with 957 conveniently selected mothers of infants when they visited a public health center in Seoul to have their children immunized. RESULTS: The average item score for the Childcare Stress Inventory was 38.03, for the Edinburgh Postnatal Depression Scale, 9.31 and for the Degree of Bother Inventory, 23.42. The CSI was positively correlated to EPDS (r=.44, p<.001) and DBI (r=.40, p<.001). Also these two variables explained 30.0% of CSI in infants' mothers. CONCLUSION: These findings are expected to expand the understanding about postpartum mothers' child-care stress and can contribute to the development of comprehensive interventions based on community health nursing.

Psychological and Spiritual Factors Associated with Death Anxiety of Elderly People Living at Home / 정신간호학회지

PURPOSE: The study was done to investigate psychological spiritual factors related to death anxiety of elderly living at home. METHODS: A descriptive correlation study was conducted. The participants were 494 living at home elderly people conveniently selected in Seoul and Kyunggi province. Data were collected using self-administered questionnaires. Descriptive statistics, t-test, ANOVA, correlation and stepwise multiple regression were used for data analysis. RESULTS: The death anxiety positively correlated with depression and negatively with self-integrity, readiness of death, belief in life after death, and spiritual well-being. The factors influencing death anxiety were self-integrity, readiness of death, depression, and belief in life after death. Those four variables explained 21.6% of death anxiety. CONCLUSION: It is expected to serve as a useful tool for nurses who serve elderly people in the clinical field and local community to help get a better understanding of death, and it is expected to lay a theoretical foundation for the development of strategies geared toward alleviating death anxiety.

Psychological and Spiritual Factors Associated with Death Anxiety of Elderly People Living at Home / 정신간호학회지

PURPOSE: The study was done to investigate psychological spiritual factors related to death anxiety of elderly living at home. METHODS: A descriptive correlation study was conducted. The participants were 494 living at home elderly people conveniently selected in Seoul and Kyunggi province. Data were collected using self-administered questionnaires. Descriptive statistics, t-test, ANOVA, correlation and stepwise multiple regression were used for data analysis. RESULTS: The death anxiety positively correlated with depression and negatively with self-integrity, readiness of death, belief in life after death, and spiritual well-being. The factors influencing death anxiety were self-integrity, readiness of death, depression, and belief in life after death. Those four variables explained 21.6% of death anxiety. CONCLUSION: It is expected to serve as a useful tool for nurses who serve elderly people in the clinical field and local community to help get a better understanding of death, and it is expected to lay a theoretical foundation for the development of strategies geared toward alleviating death anxiety.

A Study on Gender-role Identity and Cyber Delinquency in High School Students / 정신간호학회지

PURPOSE: The purpose of this study was to explore gender-role identity and cyber delinquency in high school students. METHODS: Data were collected through self-administered questionnaires and analyzed by descriptive statistics, t-test, and ANOVA. The data survey was conducted with 1,208 conveniently selected high school students in Seoul, Gyung-gi and Chung-chung province. RESULTS: The cyber delinquency score was 38.94 and androgyny gender role identity was most common (34.0%). There were significant differences in cyber delinquency by academic year, gender, school record, economic status, educational background of parents, experiences of smoking, drinking, runaway, and gender-role identity. According to gender-role identity, the masculinity group showed highest cyber delinquency and the undifferentiated, androgyny, and femininity groups followed respectively. CONCLUSION: These findings are expected to make a contribution to creation of ideal interventions and to help discover early stage cyber delinquency in high school students as approached by gender role identity.

A Study on Gender-role Identity and Cyber Delinquency in High School Students / 정신간호학회지

PURPOSE: The purpose of this study was to explore gender-role identity and cyber delinquency in high school students. METHODS: Data were collected through self-administered questionnaires and analyzed by descriptive statistics, t-test, and ANOVA. The data survey was conducted with 1,208 conveniently selected high school students in Seoul, Gyung-gi and Chung-chung province. RESULTS: The cyber delinquency score was 38.94 and androgyny gender role identity was most common (34.0%). There were significant differences in cyber delinquency by academic year, gender, school record, economic status, educational background of parents, experiences of smoking, drinking, runaway, and gender-role identity. According to gender-role identity, the masculinity group showed highest cyber delinquency and the undifferentiated, androgyny, and femininity groups followed respectively. CONCLUSION: These findings are expected to make a contribution to creation of ideal interventions and to help discover early stage cyber delinquency in high school students as approached by gender role identity.

The Relationship of Sexual Satisfaction and Daily Stress in the Breast Cancer Patients / 성인간호학회지

PURPOSE: The purpose of this study was to investigate the correlation of sexual satisfaction and daily stress in breast cancer patients. METHODS: Data was collected through self-administered questionnaires and analyzed by descriptive statistics, t-test, ANOVA and Pearson's correlation. Data survey was conducted with 500 conveniently selected breast cancer patients who visited the out patient department in 5 university hospitals in Seoul, Gyung-gi and Gang-won province. RESULTS: The sexual satisfaction of breast cancer patients score was 31.34 and there were significant sexual satisfaction differences by age, education level, menopause and sexual activity frequency. Sexual satisfaction was negatively related with daily stress (r = -.177) especially personal stress (r = -.155), economic stress (r = -.138), stress of self (r = -.181), family stress (r = -.154) and stress about leisure (r = -.139). CONCLUSION: These findings are expected to make a contribution to creation of ideal sexual rehabilitation nursing interventions for breast cancer patients care nurse. Furthermore continuous and customized education and counseling programs can contribute to promote healthy sexual life for breast cancer patients.

Long-term radiographic evaluation of GTR treatment in intrabony defect / 대한치주과학회지

Periodontal surgery as part of the treatment of periodontal disease is mainly performed 1) to gain access to diseased areas for adequate cleaning; 2) to achieve pocket reduction or elimination; and 3) to restore the periodontal tissues lost through the disease; i.e., a new attachment formation of periodontal regeneration. To accomplish the latter, often referred to as the ultimate goal of periodontal therapy, a number of surgical procedures have been advocated throughout the years. Clinical studies have demonstrated that considerable gain of clinical attachment and bone can be achieved following guided tissue regeneration (GTR) therapy of intrabony defects. The aim of this study was to analyse the radiographic bone changes 2-year after GTR using a bone graft material and nonresorbable membrane. Patients attending the department of periodontics of Kyungpook National University Hospital were studied. Patients had clinical and radiographic evidence of intrabony defect(s). 33 sites of 30 patients aged 32 to 56 (mean age 45.6) were treated by GTR with a bone graft material and nonresorbable membrane. Baseline and 2-year follow-up radiographs were collected and evaluated for this study. Radiographic assessment includes a bone fill, bone crest change, defect resolution, and % of defect resolution. Pre- and post-treatment differences between variables (maxilla and mandible, defect depth, defect angle, bone graft materials) using the paired t-test were examined. We observed 2.86+/-1.87mm of bone fill, 065+/-0.79mm of crestal resorption, 3.49+/-2.11mm of defect resolution, and 44.42+/-19.51% of percentage of defect resolution. Mandible, deeper initial defect depth, narrower initial defect angle showed greater bone fill, defect resolution, and % of defect resolution. But no difference was observed between xenograft and allograft. Outcome of GTR as a therapy of intrabony defect was better than other therapy, but herein, good oral hygiene maintenance as a anti-infective treatment and periodic recall check of patients are essential.

Trichostatin A-mediated upregulation of p21

Histone deacetylase inhibitors (HDIs), a new class of anti-cancer agents, have been reported to suppress formation of osteoclast precursors and their fusion into multinucleated cells. However, little is known about the effect of HDIs on mature osteoclasts, which may have significance for their therapeutic use. Here, we demonstrate a novel action of HDIs on osteoclast apoptosis. Primary multinucleated mature osteoclasts were prepared from mouse bone marrow cells. Treatment of osteoclasts with the HDI trichostatin A (TSA) caused apoptosis, as confirmed by annexin V staining and caspase activation. TSA caused the upregulation of p21WAF1 in osteoclasts. To understand the role of p21(WAF1) upregulation in TSA-treated osteoclasts, shRNA against p21(WAF1)-containing lentivirus was introduced into osteoclasts. The suppression of p21(WAF1) decreased TSA-directed osteoclast apoptosis. Collectively, our results provide evidence that TSA causes osteoclast apoptosis, which involves, in part, TSA-induced upregulation of p21(WAF1), and strongly supports HDIs as potential therapeutic agents for excessive bone resorption.

Screening of genes differentially expressed in cultured human periodontal ligament cells and human gingival fibroblasts / 대한치주과학회지

Periodontal ligament(PDL) cells and human gingival fibroblasts(HGFs) play important roles in development, regeneration, normal function, and pathologic alteration. PDL cells and HGFs have the similarity related with general characteristics of fibroblast such as spindle shaped morphology, the presence of vimentin intermediate filament and the synthesis of interstitial collagens and fibronectin. There were many studies about the differences between PDL cells and HGFs, but they were not about whole gene level. In this study, we tried to explain the differences of gene expression profiles between PDL cells and HGFs, and the differences among three individuals by screening gene expression patterns of PDL cells and HGFs, using cDNA microarray. Although there were some variants among three experiments, a set of genes were consistentely and differentially expressed in one cell type. Among 3,063 genes, 49 genes were more highly expressed in PDL cells and 12 genes were more highly expressed in HGFs. The genes related with cell structure and motility were expressed more highly in PDL cells. These are cofilin 1, proteoglycan 1 secretory granule, collagen type I(alpha1), adducin gamma subunit, collagen type III(alpha1), fibronectin, lumican(keratan sulfate proteoglycan), and alpha-smooth muscle actin. Tissue inhibitor of metalloproteinase known as the enzyme controlling extracellular matrix with matrix metalloproteinase is more highly expressed in PDL cells, osteoprotegerin known as osteoclastogenesis inhibitory factor is more highly expressed in HGFs. We performed northern blot to verify cDNA microarray results on selected genes such as tissue inhibitor of metalloproteinase, fibronectin, osteoprogeterin. The result of northern blot analysis showed that each cell expressed the genes in similar pattern with cDNA microarray result. This result indicates that cDNA microarray is a reliable method in screening of gene expression profiles.

The Study on Sexual Permissiveness, Family Function and Parent-Adolescent Communication in Adolescents / 아동간호학회지

PURPOSE: This study was done to examine the relationship between sexual permissiveness, family function and parent-adolescent communication among adolescents. METHOD: A descriptive correlation approach was used and the participants were 956 male and female students. Data were collected by questionnaire survey using convenience sampling. The instruments were the Family APGAR Questionnaire by Smilkstein(1978), PAC by Olson and Barnes(1982), and the Premarital Sexual Permissiveness Questionnaire by Reiss(1967). Data were analyzed using the SPSS 10.0 program with descriptive statistics, Pearson correlation coefficients, t-test, and ANOVA. RESULTS: Family function was significant according to school record, economic status, living arrangement of parent. Parent-Adolescent Communication was significant according to religion, economic status, having a boy/girl friend, and experience of sexual intercourse. Sexual permissiveness was significant for all except economic status. Correlation among the variables showed that parent-adolescent communication was negatively correlated to sexual permissiveness(r=-.127, p=.000) and positively to family function(r=.368, p=.000). CONCLUSION: The findings suggest that parent-adolescent communication and family function are associated with sexual permissiveness, and the findings of this study are expected to make a contribution to creating an ideal sexual culture for youth.

The Effect of Balance Taping Therapy on Pain of the Lower Back Pain Patient / 성인간호학회지

PURPOSE: The purpose of this study was to examine the effect of balance taping procedures on lower back pain. METHOD: This study is nonequivalent control group pretest-posttest design of quasi-experimental study. From May in 2004 to July in 2004, the research was done for females who have lower back pain in Gyeonggi province. Experimental group was 37, and control group was 36. The degree of lower back pain and that of the pain on activity of daily living(ADL) were each measured two times. RESULT: In the experimental group, the lower back pain score before taping was 6.38, that of 1 hour after the taping applied was 3.27. The lower back pain score of experimental group was significant statistically decreased and that of control group was almost not changed. Moreover, the pain score on ADL was statistically decreased in experimental group. Therefore balance taping is effective to reduce lower back pain and to improve ability of ADL. CONCLUSION: This study supports that balance taping may benefit individuals with lower back pain and balance taping therapy can be used as an independent nursing intervention. However, a larger study is in need to provide definite evidence and to determine long-term effects.

A Study on Levels of Awareness of Nosocomial Infection and Management Practices by Operating Room Nurses / 기본간호학회지

PURPOSE: This study was done to examine the awareness and management practice of operating room nurses, to prevent nosocomial infection, to identify problems and to propose solutions. METHOD: The research tools used were the hospital infection control guideline and a modified version of the measurment tools used in the study of Cho (1998). The questionnaire consisted of questions on hand washing, personal hygiene and clothes control, cleaning and environment control, sterilizing supplies and disposal of contaminated materials. The collected data were analysed with the SPSS program. RESULTS: The mean score for domain-specific awareness of nosocomial infection control was 4.81 out of a possible 5 points. The highest score was for sterilizing supplies and disposal of contaminated materials. The mean score for domain-specific practices of nosocomial infection control was 4.40, out of a possible 5 points. Sterilizing supplies and disposal of contaminated materials had the highest scores. The mean score for awareness in all domains was higher than mean score for practice. Among the general characteristics of the nurses, high awareness was found only in the provision of infection control guidelines and it had shown statistically significant difference. Examination of relation of general characteristics to practice showed that for age, career, the provision of infection control guidelines, and experience in infection control education there were statistically significant differences in the scores. For the relation between awareness of nosocomial infection control and practice, positive correlation was found in all domains, thus high awareness leads to high practice. CONCLUSION: Considering the result of this research, plans are needed that promote virtual practice of hospital infection control.

The Correlational Study on School Adjustment, Sensation Seeking and Sexual Allowance among Adolescents who are in High School / 아동간호학회지

The purpose of this study was to examine to what extent teenagers accepted sexual relations, and to determine in which way that was affected by their disposition of stimuli, one of the psychological factors, and by their adjustment to school life, one of the environmental factors, as those factors seemed to have impact on that. This study was of descriptive correlational approach, and the subjects were 962 boy and girl students randomly selected from regular and business high schools. The data were collected from May through July 2002, and SPSS win 10.0 program was employed for data analysis. The major findings of this study were as follows; First, the students investigated got a mean of 44.49 marks on school adjustment. Their sensation seeking got an average of 130.10 marks. Their sexual allowance got a mean of 38.90 marks. Second is to regard the influence of their general characteristics on school adjustment, sensation seeking and sexual allowance. school adjustment was significant on gender, grade, career track, religion, school record, economic state, sexual intercourse. Sensation seeking was significant on all of their general characteristics. Sexual allowance was significant on all except economic state. Third, concerning correlation among sexual allowance, school adjustment and sensation seeking, sexual allowance was positively correlated to sensation seeking and negatively to school adjustment. The above-mentioned findings suggested that school adjustment and stimuli pursuit was associated with sexual attitude, and the findings of this study are expected to make any contribution to creating an ideal sexual culture for the youth.

A Study of Subjectivity in the Perception Gender Roles of Women / 여성건강간호학회지

PURPOSE: This study is to define the structural patterns of gender roles of women as perceived by co-eds. METHOD: Q-methodology was used on 174 statements collected through interviews with women aged between 20 and 50. 38 Q-samples were selected from 330 Q-population. The Q-samples were administered to 29 co-eds. RESULT: Analysis of Q-type obtained by QUANAL program revealed three types of subjectivity in the perception of gender roles. Type 1, role is characterized by the tendency to play down the female gender role and think that women's body is an essential factor in forming the female gender role. Type 2, rejects motherhood image obedience and chastity dictated by male chauvinism. Type 3, shows a tendency to believe that female gender cannot be separated from maternity and that women's basic role is housekeeping. The three types were common in believing in self-development and equal rights through economical independence.

A Study on Self-Efficacy and Quality of Life in the Elderly Patients with Chronic Pain / 기본간호학회지

The subjects of this study were 100 elderly people who were over 60 years of age and had chronic pain. The study examined the matter of quality of life and self-efficacy of elderly patients with chronic pain including the influence of related factors on these variables. Also, by examining their relation, it provides basic data for the development of efficient nursing interventions for the elderly patients with chronic pain. The tools were the general self-efficacy scale by Sherer & Maddux(1982) and a specific self-efficacy Scale(Lorig et al, 1989) modified to better suit the subjects of this study. The quality of life scale by You-Ja Ro(1988) modified to better suit the subjects of this study was used. The data were collected from August to October 1999. Four researchers and two research assistants developed a data collection protocol subjected to a pilot study for confirmation of validity. In this study, the research assistants read the questionaire to the subjects and recorded the responses themselves. The interviews lasted 40-50 minutes on an average. The data thus collected were analyzed in terms of t-test, ANOVA, Pearson's correlation coefficient, using the SAS PC program. The major findings are as follows: 1) For self-efficacy it was found that males had higher self-efficacy than females for specific self-efficacy. But for general efficacy, males and females showed similar results. The the quality of life was found to be higher for males than females. 2) A positive correlation was identified between the specific self-efficacy, general self-efficacy and quality of life. 3) The general characteristics affecting the self-efficacy of elderly patients with chronic pain were employment, age, level of education, spouse, economic status and income. Self-efficacy was higher among those who were employed, aged between 66-70, well-educated, married and rich or having their own income. 4) The general characteristics affecting the quality of life of elderly patients with chronic pain were lodging with children, religion, level of education and economic status. The quality of life was higher among those who lived with their children and were Buddhists, were well-educated and rich.

Caring Experience of Mothers with IDDM Children / 간호학회지

This study is to define the caring experience of mothers with insulin-dependent diabetes mellitus children, by finding core category, contextual factors, intervening factors, and the patterns of caring, and to develop a practice theory on it. Research method followed grounded theory methodology by Strauss and Corbin. Subjects were six mothers, whose children have had insulin-dependent diabetes mellitus for 4 months to 14 years by the interview time. They were selected by theoretical sampling. Data were collected from September, 1995 to January, 1996. Interview were done by long interview took 50 minutes to 2 hours. Content of interview was recorded and transcribed later. Based on the results of previous interview, content of next interview was planned until data reached to the saturation point. Results were as follows : One hundred and forty concepts were found. These concepts were grouped into thirty-three categories, and then to ten categories. Mothers with diabetic child were revealed to face "being overwhelmed by burden". Overwhelming by burden is found to be progressed through the cycle production-coping-decrease or in crease process. Mothers showed four patterns of adaptation in caring the diabetic children. 1) If mothers felt large amount of overwhelming by burden because of difficulty of caring and unsympathizing but they had sufficient support, no condition of the child, and their coping mechanism was positive, most of them overcome with strong will, but some fell into burnout. 2) If mothers felt large amount of overwhelming by burden because of difficulty of caring, unsympathizing, insufficient support, serious condition of the child, and their coping mechanism was negative, they fell into burnout by coping with feeling. 3) In mothers felt small amount of overwhelming by burden because of little difficulty of caring and sympathizing, sufficient support, no serious condition of the child, but their coping was negative, most of them fell into burnout by coping with feeling, but some overcome. 4) If mothers felt small amount of overwhelming by burden because of little difficulty of caring and unsympathizing, sufficient support, no serious condition of the child, and their coping was positive, they overcome with strong will. On the basis of the above result, in order to help mothers take good care of their children, nursing assesment and intervention on life readjustment, and getting support should be required. Especially, through understanding mothers' personalities, individual support consistent with each of them should be required. Therefore education, counseling, mutual support and exchange of information will have to be accomplished.

A Study on the Educational Effects on Child-Raising Knowledge and Satisfaction with Out-Patient Care of Mothers with Ill-Child / 아동간호학회지

The purpose of this study were to find out the practical way to enlarged child-raising knowledge and to enhance their satisfaction with out-patient care by evaluating how effectively the education is done by nurses for mothers with ill-child and how their satisfaction with out-patient care changed. This study was designed as a Nonequivalent Control Group study. The subjects studied were consisted of the experimental and control group. Each consisted of 50 mothers with ill-child in pediatric department at one university hospital in Seoul. The period of this study is from May 20, 1996 to June 28, 1996. The first data were collected fro both of experimental and control groups in which mothers with ill-child come to the hospital for the first time. After this being done, the experimental group had been educated by the planned program and then the second data were collected from them. On the contrary, as for the control group, there had been no education and the second data were collected on the same method. The data analysis was done by SPSS program. The results of this study are as follow, 1. The child-raising knowledge level of mothers with education was higher than that of with no education.(t=18.84, df=49, p=0.000) 2. The satisfaction with out-patient care level of mothers with education was higher than that of no education.(t=10.51, df=49, p=0.000) Based on these results, I suggest as follow, 1. The research on the patients and their family should be made not only in pediatric department, but in every out-patient department. 2. For more effective education, it is required for all out-patient nurses to research the education demand of patients and their family. 3. To increase the effect of education, there must be the consultation room in out-patient department. 4. The meetings with the mothers with ill-child of the same illness have to be established and periodical education must be executed. 5. Audio-visual education programs like video tapes are needed to make use of waiting time for the medical treatment. 6. On-line consulting program are needed.