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Mem. Inst. Oswaldo Cruz ; 110(1): 145-147, 03/02/2015. graf
Статья в английский | LILACS | ID: lil-741613

Реферат

Trichuris trichiura is a soil-transmitted helminth which is prevalent in warm, moist, tropical and subtropical regions of the world with poor sanitation. Heavy whipworm can result either in Trichuris dysenteric syndrome - especially in children - or in a chronic colitis. In heavy infections, worms can spread proximally and may cause ileitis. Here we provide first microscopic evidence for a T. trichiura adult worm embedded in the rectum of a post-Colonial Brazilian adult mummy. During Colonial and post-Colonial times, many European chroniclers described a parasitic disease named Maculo whose symptomatology coincides with heavy helminthiasis. Based on our findings and on comparison of ancient textual evidence with modern description of heavy whipworm, we feel confident in considering that the two syndromes are expressions of the same pathological condition.


Тема - темы
Animals , Female , Male , Mice , Dietary Supplements , Diabetes Mellitus, Experimental/diet therapy , Hyperglycemia/prevention & control , Hypoglycemic Agents/therapeutic use , Liriope Plant/chemistry , Plant Tubers/chemistry , Polysaccharides/therapeutic use , Diabetes Mellitus, Experimental/blood , Diabetes Mellitus, Experimental/metabolism , Diabetes Mellitus, Experimental/pathology , Dietary Supplements/adverse effects , Ethnopharmacology , Gene Expression Regulation, Enzymologic , Hypoglycemic Agents/administration & dosage , Hypoglycemic Agents/adverse effects , Hypoglycemic Agents/isolation & purification , Insulin Resistance , Liver Glycogen/metabolism , Liver/enzymology , Liver/metabolism , Liver/pathology , Medicine, Chinese Traditional , Pancreas/metabolism , Pancreas/pathology , Plant Extracts/administration & dosage , Plant Extracts/adverse effects , Plant Extracts/isolation & purification , Plant Extracts/therapeutic use , Polysaccharides/administration & dosage , Polysaccharides/adverse effects , Polysaccharides/isolation & purification , Random Allocation , Rats, Wistar , Toxicity Tests, Acute
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