Incidence of Osteoporosis and Falls and Predictors of Fracture Risk in Postmenopausal Women

PURPOSE: The purpose of this study was to investigate the incidence of osteoporosis and falls and their consequences, and to identify predictors of fracture risk in the postmenopausal women. METHODS: A total of 687 postmenopausal women were recruited through a stratified convenience sampling. A structured questionnaire was used to obtain osteoporosis and fall history and details of their most recent fall. To predict fracture risk factors, we collected demographic and physical health variables related osteoporosis and fall. Fracture risk was measured by FRAX(R) to calculate 10-year probability of major osteoporotic and hip fracture. RESULTS: The prevalence of osteoporosis was 22.1%, and 66.4% of them had treatments for osteoporosis. The incidence of falls during the past year was 19.2% and 38.6% of those who fell suffered consequent fractures. Women with history of osteoporosis and falls were significant predictors of 10-year probability of major osteoporotic and hip fracture. Other significant predictors were history of fracture, chronic disease, surgical menopause, lower BMI, poorer perceived health and no job. CONCLUSION: It appears that history of osteoporosis and falls are main predictors of fracture risk. Nursing assessment should be performed by detail history taking for osteoporosis, fall, chronic disease, and fracture to screen fracture risk group among postmenopausal women.

Depression of Married and Employed Women Based on Social-Role Theory

PURPOSE: This study was based on social-role theory, and purposes were to investigate (1) how depression and health determinants vary with married and employed women, and (2) what factors contribute to depression according to family cycle. METHODS: A stratified convenience sample of 765 married and employed women was recruited during May to August 2010. Study variables of depression, socio-demographic threatening factors, psycho-stimulating factors, and social-role related factors were measured via a structured questionnaire. RESULTS: Prevalence rate for depression was 18.6%, with highest rate (25.4%) from elementary laborers. Greater levels of depression were related to women's occupation, higher life stress, and poorer health; lower social support and vulnerable personality; higher levels of social-role related stress. From multivariate analysis, women with preadolescents were the most vulnerable to depression affected by occupation, life stress, personality, and parenting stress. These factors (except for occupational class) combined with economic status, social support, and housework unfairness were significant for depression in women with adolescents. CONCLUSION: Depression among married and employed women differs by psycho-stimulating and social role relevant factors in addition to occupational class and family life cycle. Female elementary laborers and women with children need to have the highest prioritization for community mental health programs.

Effectiveness of web based learning program on self efficacy, knowledge, and competence in measurement of blood pressure / 기본간호학회지

PURPOSE: This study was done to identify the effectiveness of a web based learning program on self efficacy, knowledge, and competence in measurement of blood pressure in college nursing students. METHOD: This study was an experimental research study. Data were collected from April 20 to June 1. 2011. The participants were 68 first year nursing students (experimental group 37, control group 31). The collected data were analyzed with the PASW 18.0 program, using chi2-test, t-test, and Cronbach's alpha. RESULTS: The mean score for self efficacy in blood pressure measurement in the experimental group was 61.9 and in the control group 60.7. This result was statistically significant (t=3.301, p=.002). The mean score for knowledge of blood pressure measurement in the experimental group was 11.5 and in the control group 10.8. This result was statistically significant (t=2.910, p=.005). But effectiveness of competence in blood pressure measurement was not significant. CONCLUSION: The study results show that the web based learning program was effective for self efficacy and knowledge in blood pressure measurement but not for competence indicating.-a need to develop strategies to improve competence in blood presessure measurement for these students.

Student Experience and Satisfaction with Clinical Nursing Practice in Women's Health Nursing / 여성건강간호학회지

PURPOSE: The purpose of this study was to identify students' experiences of performance and their satisfaction with clinical nursing practice in Women's health nursing. METHODS: Data was collected using questionnaire consisting of 104; 89,; and 82 nursing activities with 12; 10; and 7 domains for delivery floor, obstetric, and gynecologic wards retrospectively. Five hundred ninety nursing students from 10 four year and one three year colleges, were recruited and selected for data collection. RESULTS: Site specific core nursing activities among top 15 items of performed experience were: interpreting fetal monitoring; massage for pain reduction; breathing technique; perineal pad change; non stress test; manual check for uterine contraction; and position change for the delivery floor. Experiences of clinical nursing practice for the obstetric ward and the gynecologic ward were identified and ranked as well. Observation of delivery, measurement & test during labor and observation of anesthesia and operation were the highest ranked activity domains of satisfaction for delivery floor, obstetric and gynecologic wards retrospectively. CONCLUSION: Discussions are needed to standardize curriculum for clinical practice in women's health nursing initiated at the level of Korean Society of Womens' Health Nursing by reflecting this result. Strategic approaches are emphasized in order to enhance a collaboration between clinical fields and colleges.

Effect of Clinical Practice Orientation Program on Anxiety, Self-Esteem and Self-Efficacy in College Students in Nursing / 기본간호학회지

PURPOSE: This study is done to identify how a clinical practice orientation program would affect anxiety, self-esteem and self-efficacy in college students in nursing. METHOD: Data was collected from 127 nursing students in February, 2008. The collected data were analyzed with the SPSS/Win 12.0 program, using t-test, ANOVA, paired t-test and Pearson's correlation coefficients. RESULTS: The total mean scores were; anxiety 53.22/80, self-esteem 29.51/40 and self-efficacy in 59.76/85. Self-esteem and self-efficacy level were significantly different according to the level of Fundamentals practice and satisfaction with nursing as a major satisfaction(p=.001). The effect of the orientation program on clinical practice were a significantly increased in self-esteem and self-efficacy (p=.000). But in terms of anxiety, the effect was the opposite. So study to identify other factors causing anxiety and strategies to reduce the anxiety need to be considered. CONCLUSION: It is important to improve self-esteem and self-efficacy and the study results indicate that an orientation program is one strategy that needs to be developed to meet these needs for college students in nursing.

Effects of Heme Oxygenase-1 Inducer and Inhibitor on Experimental Autoimmune Uveoretinitis

PURPOSE: Experimental autoimmune uveoretinitis (EAU) is an animal model of posterior uveitis and heme oxygenase-1 (HO-1) is a well-known anti-oxidant factor. However, there is no report a protective role of HO-1 on EAU in vivo. To verify that HO-1 is induced in EAU by interphotoreceptor retinoid-binding protein (IRBP), that an HO-1 inducers ameliorates the associated inflammation, and that an HO-1 inhibitor exacerbates this inflammation. METHODS: Forty four Lewis rats were given either 40 mol/kg hemin or 40 mol/kg SnPP (tin protoporphyrin IX) by intraperitoneal injection and twenty two uveitis control rats were injected with 0.5 mL of saline once daily 5-20 days after IRBP immunization inducing EAU. Three normal control rats were used for Western blotting and ELISA assay of HO-1. The clinical uveitis signs of inflammation were scored in the three groups from 0 to 4 on alternate three days. To confirm the clinical results, histological and immunohistochemical stain of HO-1 were performed on the day of peak inflammation and Western blotting and ELISA assay of HO-1 were performed on 6th, 12th and 18th day after IRBP immunization. RESULTS: Hemin, an inducer of HO-1, ameliorated the clinical signs of EAU. In contrast, SnPP-treated rats show that the severity of the clinical sign were exacerbated at the peak period of the disease. These results are roughly compatible with histological, immunoblotting, and immunohistochemical evaluations and an ELISA assay of HO-1. CONCLUSIONS: We suggest that HO-1 plays an important protective role in EAU.

The Clinical Competence and Related Factors of the Nursing Students: Focused on the Subjects Who Studied Problem-Based Learning / 성인간호학회지

PURPOSE: This study was to evaluate clinical competence in relation to self-directed learning, critical thinking disposition, and participating in PBL(Problem-Based Learning) group activities of nursing students. METHODS: Data were collected from 108 nursing students in Oct. 2006. RESULTS: Clinical competence had a significant positive correlation with self-directed learning, critical thinking disposition, and participation in PBL group activities. There was a significant difference in clinical competence according to interpersonal relationship. Participation in PBL group activities was the most influential factor of clinical competence(R2=.34). Also, the influence of clinical competence increased with the addition of self-directed learning(R2=.42). CONCLUSION: It is essential to encourage the self-directed learning and participation in PBL group activities for the improvement of clinical competence. It is relatively important for clinical competence to consider the educational environment systematically.

Effect of Self-Efficacy Promoting Program on Self-Efficacy, Metabolic Control and Self-Care Behaviors in Patients with NIDDM / 재활간호학회지

PURPOSE: The purpose of this study is to investigate the effect of Self-Efficacy Promoting Program on Self-Efficacy, Metabolic Control and Self-Care Behaviors in Patients with NIDDM. METHOD: Data was collected from March 15th to July 15th, 2001. The subjects of the study consisted of 23 NIDDM patients who had visited regularly the endocrinology out-patient department of Gwangju Christian Hospital. The instrument used in the study Paek's self-efficacy measurement scale, was modified by the researcher, self-care behaviors were created by health care teams, and HbA1c for the sugar metabolic control were measured from the patients blood. The Interventions of the self efficacy promoting program were applied 4 hours a week for 6weeks. Data were analyzed with SPSS/PC+, using T-test and Wilcoxon rank sum test. RESULT: The mean score for self-efficacy was 70.61+/-15.48 of a 140 point scale, the mean score for HbA1c level was 8.07+/-1.86%. The self efficacy promoting program significantly increased the score of self efficacy (Z=-4.198, P=.000). And the self efficacy promoting program was significantly decreased in metabolic control (Z=-2.585, p=.010). Taking medicine and controlling alcohol were the best self care behaviors of this program. CONCLUSION: It was established that the self efficacy promoting program was effective for improving self efficacy, metabolic level and self care behaviors in patients with NIDDM.

A Case of Hemorrhage from a Diverticulum of the Appendix

Diverticulum of the vermiform appendix is infrequently encountered, and in the absence of inflammation, it has been reported to be asymptomatic. Furthermore, hemorrhage from an appendiceal diverticulum is extremely rare, and has not yet reported in our country. We report a case of hemorrhage occurring in appendiceal diverticulum.

A Grounded-theory Approach to the Process of Life Adaptation in Women with Cervical Cancer* / 여성건강간호학회지

PURPOSE: The purpose of this study was to explore and describe the process of life adaptation in women with cervical cancer. METHOD: A grounded theory method with guided data collection and analysis was used. Fifteen women with cervical cancer who had some kind of treatment at the hospital were asked open-ended and descriptive questions with a guideline. All interviews were tape-recorded and transcribed verbatim. RESULT: The core category that emerged from the comparative analysis was "overcoming cancer" named as a process of life adaptation in the participants. The process of overcoming cancer evolved three stages - "admitting reality", "attempting health-care" and "continuing health-care". Depending on the paradigm model, the central phenomena of the experiences was "powerlessness". The internal factors motivating women to overcome cancer were "denial of cancer" and "desire for life". Strategies of overcoming cancer included "living as a cancer patient, " "selective food eating, " "steady exercising, " "getting rid of stress, " and "preparing for death". The intervening conditions, "supportive system, " "forms of life, " and "burden on family, " influenced overcoming cancer. CONCLUSION: The results of this study could help clinical nurses to understand life adaptation in cervical cancer patients and establish efficient coping strategies in dealing with the problems they face.

Change of Cerebral Blood Flow during Tilt Tests in Children with Vasovagal Syncope

PURPOSE: Syncope appears to be common. However, the mechanism of syncope is not clear. Increased vagal activity and withdrawal of sympathetic stimulation cause hypotension, bradycardia and finally loss of consciousness. The purpose of this study was to evaluate changes of cerebral blood flow velocity, blood pressure, and heart rate during tilt test in children with vasovagal syncope. METHODS: Sixty four children with a past history of syncope were evaluated. The stand up test was performed for 15 minutes after a rest at supine position for 10 minutes, followed by an 80 degrees tilt test lasting 45 minutes. If presyncope(lightheadedness, nausea, blurred vision, or sweating) or syncope occurred, the study was discontinued. 12-lead electrocardiography, echocardiography, and electroencephalography were performed. Transcranial Doppler study was performed at the middle cerebral artery with 2 MHz continuous Doppler probe in 10 children with positive tilt test. Systolic, diastolic, mean cerebral blood flow velocity, integral, and pulsatility index were measured with blood pressure, heart rate, and O2 saturation. RESULTS: The positive rate of tilt test was 31.3%(20/64). Systolic, diastolic, and mean cerebral blood flow velocity decreased significantly in absence of hypotension or bradycardia during presyncope. Time velocity integral of cerebral artery also decreased significantly. CONCLUSION: Decreased cerebral blood flow velocity can predict the presyncope manifestation. Impairment of autoregulation of cerebral blood flow might play an important role in the pathophysiology of vasovagal syncope.

A Study of the Relationship of Self-Efficacy, Knowledge, and Self-Care Behavior to Metabolic Level in Patients with NIDDM / 기본간호학회지

PURPOSE: The purpose of this study was to investigate the relationship of self-efficacy, knowledge about the disease, and self-care behavior to the metabolic level in patients with NIDDM. METHOD: Data were collected from March 15 to April 15, 2001. Participants in the study were 48 patients with NIDDM who were seen regularly at the endocrinology out-patient department of Gwangju Christian Hospital. The data were collected through individual interviews and patient blood samples. The data were analyzed with SPSS/PC+, using t-test, ANOVA, Pearson correlation coefficients and Cronbach's Alpha. RESULT: 1. The mean score for self-efficacy was 71.37+/-15.56, knowledge 15.00+/-2.84, self-care behavior 63.18+/-13.10. The mean score for HbA1c level was 7.66+/-1.77%, HDL cholesterol level, 46.22+/-13.04 mg/dl and total cholesterol level, 187.93+/-41.45 mg/dl. 2. There was a significant difference between patients with a spouse and those without one (t=-2.08, p=0.042), in knowledge according to level of obesity (t=5.14, p=0.010), duration of illness (t=3.22, p=0.031) and presence of complications related to diabetes (t=-2.58, p= 0.013). There were no significant differences in self-care behavior, but there were significant differences in sugar metabolic level according to sex (t=-2.02, p=0.050). 3. The correlation between diabetic patients' self-efficacy, knowledge and self-care behaviour and metabolic control was significantly related only to self-efficacy and self-care behavior (r=.692, p=0.000). CONCLUSION: It is necessary to improve self-efficacy, knowledge, and self-care behavior for patients with NIDDM by using nursing intervention programs to promote and maintain metabolic control.

Dysmenorrhea and Menstrual Attitudes in Adult Women / 여성건강간호학회지

The survey was conducted to look out the characteristics of menstruation and it's management, menstrual attitudes and degree of dysmenorrhea in the adult women. The subjects were 601 women, aged 20 year old and over, selected by convenient sampling. The results were as follows; 1. The mean age of the subjects was 29.1 years, the subjects were consisted of 346 unmarried and 304 delivery experienced person. 2.The characteristics of menstruation were as follows; irregular 167 person(27.8%), painful 451 person(75%), mean score of pain was 5.9 point and first day was most severe(45.1%). On the while, they have used the method to manage the pain such as "endure 50.8%", "to have a medicine 31.5%". 3.Menstrual attitudes were as follows; attitudes was negative such as it was meaningful as a woman (78.9%), only for birth a baby (51.6%), and menstruation was acceptable (42.9%), hope to get away(28.8%). 4.The degree of dysmenorrhea was a significant difference by age(F=4.0, P<0.01). Especially, in the subcategory, it was significant except for water retension. That is, lower concentration(F=2.60, p<0.05), negative affect(F=3.09, p<0.05), behavior change (F=6.41, p<0.050), pain(F=3.89, p<0.01), autonomic nerve response(F=2.80, p<0.05). We can conclude there were many women to have negative attitudes to menstruation and first day was most severe dysmenorrhea and it was different by age. From this results, we may suggest as follows; 1. We suggest the program for women to have a positive attitudes will be developed. 2. We can suggest that we need to develop the active and effective method to control dysmenorrhea in the first day during menstruation.

A Study on the Experience of Patients with Chronic Renal Failure who have Received a Kidney Transplant / 기본간호학회지

The grafting of a kidney has been found to be the best medical treatment for patients who have renal insufficiency failure, but the patients still have experienced much trouble and apprehension. This study was done to further nursing theory developing for patients who have has a kidney graft from another person. The research method followed grounded theory methodology of Strauss and Corbin. The subjects were three female and four male patients. This study done between Oct. 1997 and Mar. 1998. All of the subjects were interviewed by the author. Interview were done by the long interview technique and observation. In the process of data analysis, 'heart-boiling' was found to be the core phenomenon. The results were composed to 101 concepts. These concepts were grouped into nineteen categories, and then to twelve categories. There were 12 super-class categories as follows ; 'pain', 'heart-boiling', 'experience of dialysis', 'term of admission to a hospital', 'support of other person', 'dependence on God', 'direction', 'negative reaction', 'positive reaction', 'comfortable', 'lacking', 'acceptance'. In this process, 14 hypotheses were derived from the categories as follows. (1) The more experience with dialysis that the patients have, the stronger the heart-boiling will tend to be. (2) The less experience with dialysis the patients have, the weaker the heart-boiling will tend to be. (3) The longer admission to hospital the patients have, the stronger the heart-boiling will be. (4) The shorter the admission to hospital the patients have, the weaker the heart -boiling will be. (5) The weaker the intense-grief is, the more positive the reaction to heart-boiling the patients wall have. (6) The stronger the intense-grief is, the more negative the reaction to heart-boiling the patients will have. (7) The stronger the support of other persons that the patients have, the more positive the reaction to heart-boiling the patients will have. (8) The weaker the support of other person that the patients have, the more negative the reaction to heart-boiling the patients will have. (9) The stronger the dependence on God that the patients have, the mare positive reaction to heart-boiling the patients will have. (10) The weaker the dependence on God that the patients have, the more negative reaction to heart-boiling the patients will have. (11) The more positive thoughts that the patients have, the more positive reaction to heart-boiling the patients will have. (12) The more negative thoughts that the patients have, the more negative reaction to heart-boiling the patients will have. (13) The more positive reaction the patients have, the more free from heart-boiling the patients tend to be. (14) The more negative reaction the patients have, the less free from heart-boiling the patients tend to be. From the analysis of observed data and comparing each class, 1 concluded that there are four formula relation types between reaction of patients and heart-boiling. (1) If patients have the experience of dialysis, have a long term admission to hospital, are strong in heart-boiling, depend on God, have positive thoughts and another's strong support, they experience release by positive reaction to the intense-grief. (2) If patients have the experience of dialysis, have a short term admission to hospital, are weak in heart-boiling, do not depend on God, have negative thoughts, and have few supports from others, they experience attachment to heart-boiling thought a negative reaction. (3) If patients have the experience of dialysis, have a long term admission to hospital, are strong in heart-boiling, do not depend on God, and have negative thoughts, they experience attachment to heart-boiling through negative reaction in spite of support from another. (4) If patients have the experience of dialysis, have a long term admission into hospital, are strong in heart -boiling and sat isfaction is low, but they have positive thoughts, then they experience acceptance and harmony through the positive reaction to heart-boiling. The results of this study are expected to help the way nurses care for patients who have had a kidney graft from another.

Primary Signet Ring Cell Carcinoma of the Lung: Report of Two Cases / 대한세포병리학회지

Signet ring cell carcinoma is a variant of adenocarcinoma and has been rarely reported in the lung as a primary site. Recently, we experienced two cases of primary signet ring cell carcinoma in the lung without any other extrapulmonary lesion. Sputum cytology was performed and the tumor cells which have eccentrically located nuclei and abundnat mucinous cytoplasm were dispersed in diffuse sheets. On resected specimen, the signet ring cells occupied about 50~80% of all tumor cell nests. HIstochemical staining revealed that the mucin produced by tumor cells was mostly carboxylated acid mucins. Ultrastructurally, the tumor cells contained variable sized membrane-bound mucin granules with weak central osmiophilic density and showed numerous surface microvilli, which represented that tumor cells arose from bronchial epithelial cells. In general, this tumor has diffusely infiltrative nature and the prognosis is fatal due to widespread metastasis before clinical discovery.

Reye's Syndrome in Children

No abstract available.

Two Cases of Hemolytic Uremic Syndrome

No abstract available.

Hyperviscosity Syndrome in Newborn

We experienced Hyperviscosity syndrome in 5 newborn infants during 6 months period from August 1980 to January 1981. Diagnosis was made on the basis of characteristic clinical symp-toms along with polythemia. The following results were obtained. Sex in 5 affected infants showed male in 2 and female in 3. And gestational age showed preterm in 3 and full term in 2 cases. Predisposing factors were intertwin transfusion in 1, placental insufficiency with maternal to-xemia in 2(one of which was accompained with interwin transfusion) and small for gestational age in 1. Signs and symptoms associated with hyperviscosity syndrome were cyanosis in 3, dyspnea in 2, lethargy in 2, plethora in 1, hypocalcemia in 4, hypoglycemia in 2 and hyperbilirubinemia in 2 cases. Partial exchange transfusion was done in all cases, resulting in improvement of polycythem-ia and clinical condition, except 1 expired case.

Morphological observations on Clonorchis sinensis obtained from rats treated with praziquantel

The present study was undertaken to observe the morphological changes of Clonorchis sinensis obtained from experimentally infected rats treated with praziquantel (Biltricide) which is a new anthelmintic agent with high activity against a broad spectrum of cestode and trematode species. For this study, the rats were infected experimentally with about 50 metacercariae of C. sinensis and were given praziquantel a single dose of 600 mg per kg of body weight at 5 weeks after infection. The Clonorchis worms were isolated from the bile ducts of the rats which were autopsied on the 4th day after treatment. After isolation the parasites were observed their shape and motility in the medium of 37 C physiological saline solution, and then the fine structure of the tegument of C. sinensis was studied by means of light, scanning and transmission electron microscope. The findings of the observation were compared with those of untreated parasites. The results are as follows: All the isolated worms moved actively in the medium of physiological saline solution (37 C). A majority of the parasites obtained from the treated rats showed a large balloon shaped structure on the surface between oral and ventral suckers. But such structure has never seen in the parasites obtained from control rats. By the scanning electron microscopic observation, the regular pattern of the tegumental ridges was significantly changed on the outer surfaces of parasites obtained from the treated rats as compared with those of the control rats. By the transmission electron microscopic observation, the numerous mitochondriae in the syncytial tegumental layer of the treated parasites appeared to be degenerated and formed small vacuoles, and the tegumental ridges were also degenerated and showed somewhat flattened. In the parasites obtained from the treated rats, a different size of vacuoles interspersed in the distal part of the syncytial tegument and also in subepithelial region of the urinary bladder. These vacuoles are fused each other and lead to the disruption of the apical region of syncytial tegument along the basement layer. Finally the basement layer was dislocated. So that the tegumental layer appeared as a large balloon.

Effect of oxantel/pyrantel pamoate tablets against intestinal nematodes in Korea

A total of 48 subjects harbouring Trichuris trichiura, Ascaris lumbricoides, hookworm and/or Enterobius vermicularis were treated with oxantel/pyrantel pamoate tablets (100 mg of each) in a single dose of 20 mg base per kg of body weight. In all 37 cases of A. lumbricoides and 8 cases of A. duodenale infections cured completely, and the mean recovered worm-load was 3.8 with a range of 1-21 and 5.8 with a range of 3-9 respectively. In T. trichiura infection, 32(71.1%) of 45 cases cured completely and the average egg reduction rate was 90.8 per cent. The mean recovered worm-load was 14.6 with a rnage of 1-77 worms. On the other hand, in E. vermicularis infection, 37 (84.1 %) of 44 patients were negative eggs by anal swab tests on the 10 to 11th days and 27 (61.4%) on the 20 to 21st days after treatment. The mean recovered worm-load was 17.7 with a range of 1-62. Only one patient with Trichostrongylus orientalis treated with this drug showed no eggs in his stools throughout the post-treatment examinations. Side effects were not noted in all treated cases. These findings demonstrate that a single dose of oxantel/pyrantel pamoate tablets can be considered a drug of choice for multiple infections with these nematodes.