Реферат
La alopecia frontal fibrosante es una alopecia cicatricial que se caracteriza por la recesión de la línea de implantación frontotemporal que afecta principalmente a mujeres caucásicas en edad posmenopáusica y rara vez a hombres. Actualmente los mecanismos específicos de desarrollo continúan en estudio; sin embargo hay varias hipótesis sobre la asociación de la alopecia frontal fibrosante con otros trastornos autoinmunitarios. Se comunica el caso de un paciente masculino de 58 años con alopecia frontal fibrosante en áreas comprometidas por vitiligo. (AU)
Frontal fibrosing alopecia is a cicatricial alopecic characterized by progressive regression of the frontotemporal hairline. It usually affects postmenopausal caucasian women, and rarely men. Currently the specific mechanisms of development remain unknown, however there are several hypotheses about the association of frontal fibrosing alopecia with other autoimmune disorders. The case of a 58-year-old male patient with frontal fibrosing alopecia in areas affected by vitiligo. (AU)
Тема - темы
Humans , Male , Middle Aged , Vitiligo/complications , Alopecia/complications , Alopecia/diagnosis , Alopecia/drug therapy , Vitiligo/pathology , Clobetasol/administration & dosage , Tacrolimus/administration & dosage , Alopecia/pathology , Dutasteride/administration & dosageРеферат
Abstract: Lupus erythemathosus is a chronic, relapsing disease with acute, subacute, and chronic lesions. Effluvium telogen occurs in the setting of systemic activity of the disease, and cicatricial alopecia results from discoid lesionsin on the scalp. Other types of alopecia, like alopecia areata, may rarely be found in lupus. Frontal fibrosing alopecia is characterized by frontotemporal hairline recession and eybrow loss. Histophatologically, it cannot be differentiated from lichen planopilaris.It is controversial whether frontal fibrosing alopecia is a subtype of lichen planopilaris.. A pacient with chronic lichenoid lupus erythematosus is described with clinical, histophatological and dermoscopic features of frontal fibrosing alopecia.We have not been able to find in the literature cases of frontal fibrosing alopecia as a clinical manifestation of lupus.
Тема - темы
Humans , Female , Middle Aged , Lupus Erythematosus, Discoid/complications , Lupus Erythematosus, Discoid/pathology , Alopecia/complications , Alopecia/pathology , Scalp/pathology , Biopsy , Fibrosis/pathology , Lichenoid Eruptions/pathology , DermoscopyРеферат
Abstract: Background: Androgenetic alopecia is a common dermatological condition affecting both genders. Objective: To evaluate the tendency towards development of psychosexual disorders according to the clinical stages of androgenetic alopecia. Methods: A cross-sectional study was conducted including 353 patients of both sexes on different clinical stages of hair loss, and the patients were enquired about self-perception, self-esteem, sexual experiences, anxiety and depression states. Hair loss was classified by standardized hair loss scales, and psychological effects were assessed with questionnaires. Results were compared to p<0.05. Results: Negative effects on each psychological parameter of androgenetic alopecia in females were higher than in males. While overall comparisons according to hair loss stages for each parameter were significant in males, only sexual experiences, anxiety and depression values were significant in females. Sexual experiences and depression values were higher in Ludwig 3 than in 1&2, while anxiety was higher in Ludwig 3 than 1. Self-perception values in Norwood 2&2A were higher than 3A, 3V, 4 and 4A, while self-esteem values in 2A were higher than 3&4. Sexual experiences values in 2&2A were lower than 3, 3A, 3V, 4 and 4A, while 3&3A were lower than 4&4A. Depression was lower in 2A than 3, 3A, and 3V, and lower in 2A than 4A. Anxiety was lower in 2A than in 4&4A. Study limitations: Relatively small number of patients, who were from a single center. Conclusions: In the management of androgenetic alopecia, it should be considered that patients may need psychological support according to the clinical stages, because of increased tendency to develop psychosexual disorders.
Тема - темы
Humans , Male , Female , Adolescent , Adult , Middle Aged , Young Adult , Sexual Dysfunctions, Psychological/etiology , Alopecia/complications , Alopecia/psychology , Anxiety/psychology , Psychological Tests , Self Concept , Socioeconomic Factors , Severity of Illness Index , Sex Factors , Cross-Sectional Studies , Surveys and Questionnaires , Analysis of Variance , Age Factors , Sex Distribution , Age Distribution , Statistics, Nonparametric , Disease Progression , Depression/psychologyРеферат
Abstract We present the case of a 72-year-old Caucasian woman with frontal fibrosing alopecia of one year's duration. Eighteen months later, she presented with sudden hyperpigmentation on the submental area, neck and upper chest. Histopathological examination was consistent with lichen planus pigmentosus. This is the report of a unique case of a FFA and extrafacial lichen planus pigmentosus.
Тема - темы
Humans , Female , Aged , Hyperpigmentation/pathology , Alopecia/pathology , Lichen Planus/pathology , Skin/pathology , Hyperpigmentation/complications , Dermoscopy , Alopecia/complications , Forehead/pathology , Lichen Planus/complicationsРеферат
Abstract Frontal fibrosing alopecia is a distinctive form of scarring alopecia considered to be a clinical variant of lichen planopilaris. It predominantly occurs in postmenopausal women and has a slowly progressive course. It was first described by Kossard in 1994. Since then the number of reported cases has increased significantly. Coexistence of frontal fibrosing alopecia and autoimmune disorders - such as discoid erythematosus lupus and Sjögren's syndrome - may suggest a common pathogenic background among the diseases.
Тема - темы
Humans , Female , Middle Aged , Sjogren's Syndrome/complications , Alopecia/complications , Fibrosis , Lupus Erythematosus, Discoid/complications , Lupus Erythematosus, Discoid/pathology , Hair Follicle/pathology , Dermis/pathology , Alopecia/immunology , Alopecia/pathology , Lichen Planus/immunology , Lichen Planus/pathologyРеферат
Trichilemmal cyst, also known as "pilar cyst," is a benign cyst containing keratin and its breakdown products with a wall resembling external root sheath of hair. It occurs mostly in females as a solitary firm nodule over scalp. Occurrence of multiple trichilemmal cysts in areas other than scalp is extremely rare. We are reporting a case of a 40-years-old female who presented with multiple calcified trichilemmal cysts in multicentric distribution associated with alopecia universalis. Similar complaints were present in elder sister of the patient, indicating a genetic background. Multicentric distribution of trichilemmal cysts, calcification, familial occurrence, and association with alopecia universalis seen in our case are all rare and intriguing features.
Тема - темы
Adult , Alopecia/complications , Alopecia/genetics , Alopecia/pathology , Buttocks , Epidermal Cyst/complications , Epidermal Cyst/pathology , Female , Forearm , Humans , Scalp , SiblingsРеферат
Queratose folicular espinulosa decalvante é uma genodermatose rara, ligada ao X, caracterizada por hiperqueratose folicular, fotofobia, alopécia cicatricial do couro cabeludo e supercílios. Descreve-se o caso de paciente do sexo feminino, de 25 anos, com quadro clínico e evolução típicos desta síndrome.
Keratosis follicularis spinulosa decalvans is a rare X-linked genodermatosis, characterized by follicular hyperkeratosis, photophobia, scarring alopecia of the scalp and eyebrows. A case of a 25 yearold female with typical clinical picture and progression of this syndrome is described.
Тема - темы
Adult , Female , Humans , Alopecia/complications , Alopecia/pathology , Darier Disease/complications , Darier Disease/pathologyРеферат
The ectodermal dysplasias are a heterogeneous group of disorders with primary defect in hair, teeth, nail and sweat gland function. Numerous types have been described and several classifications exist. Here, we present a patient with ectodermal dysplasia with alopecia, dysplastic nails, hypohidrosis, sensorineural deafness, palmoplantar keratoderma, abnormal teeth and dry skin. To our knowledge, combination of all these features in ectodermal dysplasia has not been reported in the past. The etiology is unknown, but consanguinity of parents points to an autosomal recessive inheritance.
Тема - темы
Adult , Alopecia/complications , Deafness/complications , Ectodermal Dysplasia/complications , Female , Humans , Hypohidrosis/complications , Keratosis/complications , Nails, Malformed/complications , Tooth Abnormalities/complicationsРеферат
A 12-year-old boy born of a nonconsanguineous marriage presented with dry rough skin and photophobia since birth. His growth and developmental milestones were normal and there was no history of any neurological problem, hearing deficit or scarring around the hair follicles. Cutaneous examination revealed diffuse thinning of scalp hair with loss of eyebrows and eyelashes and a sandpapery texture of the skin all over the body, suggestive of ichthyosis follicularis with alopecia and photophobia syndrome.
Тема - темы
Alopecia/complications , Child , Humans , Ichthyosis/complications , Male , Photophobia/complications , SyndromeРеферат
Satoyoshi syndrome (Komuragaeri disease) is a rare disorder of presumed autoimmune etiology, characterized by painful muscle spasms, alopecia, diarrhea, endocrinopathy with amenorrhoea and secondary skeletal abnormalities. Most of the previous reports are of the Japanese people. We report the first case from India.
Тема - темы
Adult , Alopecia/complications , Anemia, Hemolytic/complications , Anticonvulsants/therapeutic use , Autoimmune Diseases/complications , Electromyography , Endocrine System Diseases/complications , Female , Humans , India , Neural Conduction , Phenytoin/therapeutic use , Prednisolone/therapeutic use , Spasm/complications , SyndromeТема - темы
Humans , Male , Female , Paresthesia/diagnosis , Scalp , Alopecia/complications , Glossalgia/complicationsРеферат
Common variable immune deficiency (CVID) is associated with a variety of autoimmune diseases. Alopecia universalis (AU), believed to have an autoimmune basis, has been found in 1.6% of patients with CVID. Intravenous immunoglobulin (IVIG) therapy is used in various immunodeficiency disorders including CVID, and benefit has been shown in the therapy of autoimmune diseases. We report a patient with CVID and AU treated with IVIG who experienced significant hair regrowth. An 8-year-old girl with CVID and AU was treated with IVIG 400 mg/kg every 4 weeks. Since her second dose of IVIG, regrowth of eyelashes, eyebrows, body and scalp hair was observed in this patient. At present, about 1 year treat-meant of IVIG, significant hair regrowth is noted with 5-6 cm of scalp hair. We believe that IVIG may be beneficial in the treatment of AU, at least in patients with CVID.
Тема - темы
Alopecia/complications , Child , Common Variable Immunodeficiency/complications , Female , Hair/drug effects , Humans , Immunoglobulins, Intravenous/therapeutic use , Treatment OutcomeРеферат
Se realiza un estudio restrospectivo sobre 27 casos de metástasis cutáneo-mucosas observados en el Servicio de Dermatología del Hospital Nacional Prof. A. Posadas (Buenos Aires, Argentina) entre los años 1988 y 1994. El primitivo más común fue el cáncer de mama, siguiéndole el hipernefroma, el cáncer de pulmón y el melanoma. Se efectúa una actualización sobre el tema.
Тема - темы
Humans , Male , Female , Adult , Middle Aged , Neoplasm Metastasis/physiopathology , Skin Neoplasms/etiology , Alopecia/complications , Breast Neoplasms/complications , Breast Neoplasms/secondary , Carcinoma, Renal Cell/complications , Carcinoma, Renal Cell/secondary , Lung Neoplasms/complications , Lung Neoplasms/secondary , Neoplasm Metastasis/diagnosis , Neoplasms by Site , Retrospective Studies , Skin Neoplasms/physiopathology , Skin Neoplasms/secondaryРеферат
An elderly man with non-familial gastrointestinal polyposis, malabsorption and progressive hypoproteinemia is reported. Associated alopecia, cutaneous hyperpigmentation and nail dystrophy with loss of nails were consistent with the diagnosis of Cronkhite-Canada syndrome. Hypothyroidism was present in this patient and the rare association of these two conditions is discussed.