Реферат
O hamartoma folicular basaloide (HFB) é um tumor anexial raro e benigno, que se assemelha ao carcinoma basocelular (CBC), e pode apresentar manifestações clínicas diversas. Uma mutação no gene PTCH, envolvido na síndrome de Gorlin-Goltz, poderia estar associada à patogênese dessa neoplasia. Descreve-se caso de menina, sete anos, apresentando múltiplas pápulas na face.
Basaloid follicular hamartoma (BFH) is a rare and benign adnexal tumor that resembles basal cell carcinoma (BCC) and may present with different clinical manifestations. A mutation in the PTCH gene, involved in Gorlin-Goltz syndrome, could be associated with the pathogenesis of this neoplasm. We describe the case of a 7-year-old girl with multiple papules on her face.
Тема - темы
Humans , Female , Child , Facial Dermatoses/diagnosis , Hamartoma/diagnosis , Immunohistochemistry , Facial Dermatoses/pathology , Hamartoma/pathologyРеферат
Abstract Lupus miliaris disseminatus faciei or acne agminata is a chronic inflammatory disorder of the skin, considered an intriguing entity due to its pathogenesis, which is still largely speculative. It has been linked to tuberculosis, sarcoidosis, rosacea, and other granulomatous diseases, but it is considered an independent entity.
Тема - темы
Humans , Rosacea/diagnosis , Facial Dermatoses/diagnosis , Skin , Diagnosis, Differential , Edema/diagnosisРеферат
El granuloma facial es una dermatosis benigna poco frecuente de etiología desconocida, generalmente asintomática, caracterizada por inflamación crónica y localizada habitualmente en zonas fotoexpuestas de la cara, con un patrón histológico característico. Si bien la respuesta al tratamiento es variable, existen múltiples opciones terapéuticas que han reportado ser efectivas en algunos pacientes. Entre estas alternativas se incluyen tratamientos sistémicos con corticoides y dapsona o tratamientos intralesionales con corticoides, crioterapia e inhibidores de calcineurina tópicos. Describimos el caso de un paciente adulto con una placa eritemato violácea asintomática en mejilla derecha, de crecimiento lentamente progresivo de dos años de evolución, clínica e histopatológicamente compatible con granuloma facial y respuesta favorable a corticoides intralesionales.
Granuloma faciale is an uncommon benign dermatosis, with unknown etiology, usually asymptomatic, characterized by chronic inflammation localized in sun-exposed areas of the face with a characteristic histological pattern. Although response to treatment is variable, there are multiple therapeutic alternatives that have been reported to be effective in some patients, including systemic treatments with steroids and dapsone or also topical treatments like intralesional corticosteroid, cryotherapy and calcineurin inhibitors, such as tacrolimus. We present the case of an adult patient with an asymptomatic erythematous-violet plaque on the right cheek, with progressive slow growth over two years, clinically and histologically and pathologically compatible with a facial granuloma. The patient responded well to intralesional corticosteroids.
Тема - темы
Humans , Male , Middle Aged , Skin Diseases, Vascular/diagnosis , Facial Dermatoses/diagnosis , Granuloma/diagnosis , Skin Diseases, Vascular/pathology , Skin Diseases, Vascular/drug therapy , Facial Dermatoses/pathology , Facial Dermatoses/drug therapy , Glucocorticoids/administration & dosage , Granuloma/pathology , Granuloma/drug therapyРеферат
Abstract: Granuloma faciale is a rare, chronic dermatologic disorder, which mainly affects the face. Recently, dermoscopy has been demonstrated as an important ancillary tool on the clinical diagnosis of facial dermatoses. We report two cases of granuloma faciale with yellow areas on dermoscopy that was not yet described in the literature, corresponding to abundant hemosiderin on histopathological examination.
Тема - темы
Humans , Male , Female , Adult , Aged , Facial Dermatoses/diagnosis , Granuloma/diagnosis , DermoscopyРеферат
Abstract Botryomycosis is an uncommon, chronic, suppurative, bacterial infection that primarily affects the skin and subcutaneous tissues. It has long been associated with defects of cellular immunity. We report a 28-year-old woman who presented with a chronic, ulcerated lesion with draining sinuses in the right malar region. Predisposing factors were HIV infection with poor immunological control, alcoholism, and a previous trauma to the right cheek. Several courses of antimicrobial therapy provided only partial and temporary remission. Complete clinical remission was only achieved 5 years later when a novel antiretroviral regimen composed of darunavir and raltegravir was initiated.
Тема - темы
Humans , Female , Adult , Pyoderma/drug therapy , AIDS-Related Opportunistic Infections/drug therapy , Botrytis/isolation & purification , Dermatomycoses/drug therapy , Facial Dermatoses/drug therapy , Pyoderma/diagnosis , AIDS-Related Opportunistic Infections/diagnosis , Anti-HIV Agents/therapeutic use , Dermatomycoses/diagnosis , Facial Dermatoses/diagnosis , Darunavir/therapeutic use , Raltegravir Potassium/therapeutic useРеферат
Abstract: Milia-like idiopathic calcinosis cutis (MICC) is a very rare dermatological disorder characterized by multiple whitish to skin colored, milia-like papules, mostly found on the hands. MICC can disappear spontaneously by adulthood; therefore, its early recognition is crucial to avoiding unnecessary interventions. Herein, we present a case of MICC in a 6-year-old girl with Down syndrome.
Тема - темы
Female , Child , Skin Diseases/diagnosis , Calcinosis/diagnosis , Down Syndrome/complications , Skin Diseases/pathology , Calcinosis/complications , Calcinosis/pathology , Dermoscopy , Facial Dermatoses/diagnosis , Facial Dermatoses/pathology , Foot Dermatoses/diagnosis , Foot Dermatoses/pathology , Hand Dermatoses/diagnosis , Hand Dermatoses/pathologyРеферат
El lupus miliar diseminado facial es una enfermedad inflamatoria granulomatosa de etiología incierta, caracterizada por pápulas eritemato-amarillentas que afectan predominantemente la región facial. Luego de 1 a 4 años puede involucionar sin tratamiento pero dejando secuelas estéticas. Existen múltiples tratamientos con respuestas variables. Presentamos un caso con respuesta favorable al tratamiento con isotretinoína, sin recaídas a la fecha, y realizamos una revisión de la literatura (AU)
Lupus miliaris disseminatus faciei is a granulomatous inflammatory disease of unknown etiology, characterized by erythematous yellowish papules predominantly affecting facial region. After 1-4 years it may involute without treatment but leaving scarring sequelae. There are multiple treatments with variable responses. A case with favorable response to isotretinoin treatment, with no relapses to date, is reported and literature review is made (AU)
Тема - темы
Humans , Female , Adult , Facial Dermatoses/diagnosis , Lupus Erythematosus, Systemic/diagnosis , Therapeutics , Diagnosis, DifferentialРеферат
Paracoccidioidomycosis and histoplasmosis are systemic fungal infections endemic in Brazil. Disseminated clinical forms are uncommon in immunocompetent individuals. We describe two HIV-negative patients with disseminated fungal infections, paracoccidioidomycosis and histoplasmosis, who were diagnosed by biopsies of suprarenal lesions. Both were treated for a prolonged period with oral antifungal agents, and both showed favorable outcomes.
A paracoccidioidomicose e a histoplasmose são infecções fúngicas sistêmicas endêmicas no Brasil. As formas clínicas disseminadas são incomuns em pacientes imunocompetentes. Nós descrevemos dois pacientes HIV-negativos com infecções fúngicas disseminadas, paracoccidioidomicose e histoplasmose, que foram diagnosticadas por biópsias de lesões de supra-renal. Ambos foram tratados por períodos prolongados com antifúngicos orais, evoluindo com boa resposta terapêutica.
Тема - темы
Humans , Male , Middle Aged , Adrenal Gland Diseases/diagnosis , Central Nervous System Fungal Infections/diagnosis , Facial Dermatoses/diagnosis , Histoplasmosis/diagnosis , Paracoccidioidomycosis/diagnosis , Adrenal Gland Diseases/microbiology , Biopsy , Brazil , Central Nervous System Fungal Infections/microbiology , Facial Dermatoses/microbiology , Immunocompetence/physiologyРеферат
Leprosy is aneasily recognizable disease due to its dermato-neurological manifestations. It must be present in the physician’s diagnostic repertoire, especially for those working in endemic areas. However, leprosy reaction is not always easily recognized by non-dermatologists, becoming one of the major problems in the management of patients with leprosy, as it presents clinical complications characterized by inflammatory process, accompanied by pain, malaise and sometimes the establishment or worsening of the patient’s disabilities. We report the case of a patient with type-1 periorbital reaction admitted to the hospital, diagnosed and treated as facial cellulitis, whose late diagnosis may have contributed to the appearance or worsening of facial neuritis.
.Тема - темы
Aged , Humans , Male , Cellulitis/diagnosis , Facial Dermatoses/diagnosis , Leprosy, Borderline/diagnosis , Biopsy , Diagnosis, Differential , Early Diagnosis , Face , Facial Dermatoses/drug therapy , Leprosy, Borderline/drug therapy , Time Factors , Treatment OutcomeТема - темы
Aged , Darier Disease/diagnosis , Darier Disease/pathology , Facial Dermatoses/diagnosis , Facial Dermatoses/pathology , Female , Forehead , HumansТема - темы
Adolescent , Cysts/diagnosis , Cysts/pathology , Facial Dermatoses/diagnosis , Facial Dermatoses/pathology , Hair , Humans , MaleРеферат
The granuloma faciale is a rare and benign skin disease of unknown etiology, characterized by chronic leukocitoclastic vasculitis. It is characterized by skin lesions predominantly facial whose course is chronic and slowly progressive. The diagnosis is based on clinical features, histopathology and, more recently, in dermoscopy. We describe the case of a male patient, 40 years old, with a sarcoid lesion on the malar site, whose histopathological examination revealed a mixed inflammatory infiltrate with presence of Grenz zone. Dermoscopy revealed a pink background with white striations. The definitive diagnosis is made by histopathologic evaluation, and dermatoscopy can be helpful. It is known to be resistant to therapy, oral medications, intralesional and surgical procedures are options.
O granuloma facial é doença cutânea rara e benigna, de etiologia desconhecida, caracterizado por vasculite leucocitoclástica crônica. Caracteriza-se por lesões cutâneas predominantemente faciais, tem curso crônico e lentamente progressivo. O diagnóstico é baseado na clínica, histopatologia e, mais recentemente, na dermatoscopia. Relatamos o quadro de um paciente masculino, 40 anos de idade, com lesão sarcoídea na face malar, cujo exame histopatológico revelou infiltrado inflamatório misto com presença de zona de Grenz. A dermatoscopia revelou um fundo rosado com estrias brancas. O diagnóstico definitivo é feito pela avaliação histopatológica, sendo que a dermatoscopia pode ser útil. É conhecida por ser resistente à terapêutica, sendo propostas medicações orais, intralesionais e procedimentos cirúrgicos.
Тема - темы
Adult , Humans , Male , Dermoscopy , Eosinophilic Granuloma/diagnosis , Facial Dermatoses/diagnosis , Anti-Infective Agents/therapeutic use , Diagnosis, Differential , Dapsone/therapeutic use , Eosinophilic Granuloma/drug therapy , Facial Dermatoses/drug therapyРеферат
Harlequin syndrome happens in only one side of the face. In the affected half, the face does not sweat or flush even with simulation. Arms and trunk could also be affected. This condition is induced by heat, exercise and emotional factors. The article reports a case of a nine-year-old female with a 3-year history of unilateral flushing and sweating after exercise; a brief literature review is included. Despite the rarity of this syndrome, dermatologists should recognize this condition and refer these patients to ophthalmological and neurological examination.
A Síndrome de Arlequim ocorre em apenas um lado da face. No metade afetada, a face não produz suor ou flushing, mesmo estimulada. Braços e tórax raramente podem ser afetados. Esta condição é geralmente induzida por calor, exercícios e fatores emocionais. O artigo relata um caso de uma menina de 9 anos de idade com uma história de 3 anos de flushing e sudorese unilaterais no rosto após exercícios e inclui uma revisão da literatura. Apesar da raridade desta síndrome, dermatologistas devem reconhecer esta condição e encaminhar estes pacientes a um exame oftalmológico e neurológico.
Тема - темы
Child , Female , Humans , Autonomic Nervous System Diseases/diagnosis , Facial Dermatoses/diagnosis , Flushing/diagnosis , Hypohidrosis/diagnosisРеферат
A ocronose exógena consiste em hiperpigmentação crônica de áreas previamente tratadas com agentes tópicos como: a hidroquinona, a resorcina, os antimaláricos e o fenol. O diagnóstico precoce permite suspender prontamente o agente causador, uma vez que as opções terapêuticas disponíveis são escassas e com resultados insatisfatórios. Reportam-se três casos de ocronose exógena na face, diagnosticados pela dermatoscopia. O estudo dermatoscópico evidenciou estruturas amorfas de coloração cinza-enegrecido, algumas obliterando as aberturas foliculares. O exame histopatológico corroborou o diagnóstico.
Exogenous ochronosis consists of chronic hyperpigmentation of areas previously treated with topical agents such as hydroquinone, resorcinol, antimalarials and phenol. Early diagnosis allows to promptly suspend the causative agent and it is imperative since the available therapeutic options are scarce and have presented so far unsatisfactory results. Three cases of exogenous ochronosis on the face which were diagnosed with the use of dermoscopy are presented. Dermatoscopy showed blackish-gray amorphous structures, some obliterating the follicular openings. Histopathological examination confirmed the diagnosis.