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1.
Chinese Critical Care Medicine ; (12): 538-544, 2023.
Статья в Китайский | WPRIM | ID: wpr-982629

Реферат

OBJECTIVE@#To systematically assess the efficacy of traditional Chinese therapy in the treatment of ICU-acquired weakness (ICU-AW).@*METHODS@#PubMed, Cochrane Library, Embase, Web of Science, CNKI, Wanfang, VIP were retrieved by computer and were used to collect a randomized controlled trials (RCT) of traditional Chinese therapy for ICU-AW. The retrieval time was from databases establishment to December 2021. After 2 researchers independently screened the literature, extracted data and evaluated the risk of bias included in the study, and RevMan 5.4 software was used for Meta-analysis.@*RESULTS@#334 articles were selected, totally 13 clinical studies and 982 patients were included, including 562 in the trial group and 420 in the control group. Meta-analysis results showed that traditional Chinese therapy could improve clinical efficacy of ICU-AW patients [relative risk (RR) = 1.35, 95% confidence interval (95%CI) was 1.20 to 1.52, P < 0.000 01], improve the muscle strength [Medical Research Council score (MRC score); standardized mean difference (SMD) = 1.00, 95%CI was 0.67 to 1.33, P < 0.000 01], improve daily life ability [modified Barthel index score (MBI score); SMD = 1.67, 95%CI was 1.20 to 2.14, P < 0.000 01], shorten mechanical ventilation time (SMD = -1.47, 95%CI was -1.84 to -1.09, P < 0.000 01), reduce the length of intensive care unit (ICU) stay [mean difference (MD) = -3.28, 95%CI was -3.89 to -2.68, P < 0.000 01], reduce the total hospitalization time (MD = -4.71, 95%CI was -5.90 to -3.53, P < 0.000 01), reduce tumor necrosis factor-α (TNF-α; MD = -4.55, 95%CI was -6.39 to -2.70, P < 0.000 01) and interleukin-6 (IL-6; MD = -5.07, 95%CI was -6.36 to -3.77, P < 0.000 01). There was no obvious advantage in reducing the severity of the disease [acute physiology and chronic health evaluation II (APACHE II; SMD = -0.45, 95%CI was -0.92 to 0.03, P = 0.07).@*CONCLUSIONS@#Based on the current research, traditional Chinese therapy can improve the clinical efficacy of ICU-AW, improve muscle strength and daily life ability, shorten mechanical ventilation, the length of ICU stay and total hospitalization time, reduce TNF-α and IL-6. But traditional Chinese therapy can not reduce the overall disease severity.


Тема - темы
Humans , APACHE , East Asian People , Intensive Care Units , Interleukin-6 , Tumor Necrosis Factor-alpha , Medicine, Chinese Traditional , Muscle Weakness/therapy
2.
Prensa méd. argent ; 108(6): 296-308, 20220000. fig, tab
Статья в испанский | LILACS, BINACIS | ID: biblio-1397095

Реферат

Introducción: La neuropatía motora multifocal con bloqueos de la conducción (NMMBC) es una enfermedad crónica inmunomediada, con un compromiso exclusivo de los nervios motores. Es importante diferenciarla de otras enfermedades que cursan con afectación motora, debido a que ésta es una enfermedad tratable. Cuadro clínico: Paciente varón de 56 años, con compromiso motor progresivo en el miembro superior del lado derecho desde el año 2016. El examen neurofisiológico demostró la presencia de múltiples bloqueos de la conducción nerviosa. Los anticuerpos antigangliósidos fueron negativos. Se indicó tratamiento con inmunoglobulina endovenosa en varios ciclos, con mejoría progresiva del cuadro. Discusión: Se discute el plan diagnóstico clínico y electrofisiológico, los diagnósticos diferenciales, las hipótesis fisiopatológicas y el tratamiento de esta enfermedad de rara ocurrencia


Introduction: Multifocal motor neuropathy with conduction blocks (NMMBC) is a chronic immunemediated disease that exclusively involves the motor nerves. It is important to differentiate it from other diseases that present with motor involvement, because this is a treatable disease. Clinical picture: A 56-year-old male patient, with progressive motor involvement in the right upper limb since 2016. A neurophysiological examination revealed multiple nerve conduction blocks. Antiganglioside antibodies were negative. Treatment with intravenous immunoglobulin was indicated for several cycles with progressive improvement of the condition. Discussion: Clinical and electrophysiological diagnostic plans, differential diagnoses, pathophysiological hypotheses, and treatment of this rare disease are discussed


Тема - темы
Humans , Male , Middle Aged , Immunoglobulins/therapeutic use , Muscular Atrophy/immunology , Muscle Weakness/therapy , Diagnosis, Differential , Neural Conduction/immunology
3.
Rev. chil. anest ; 51(1): 47-54, 2022. ilus, tab
Статья в испанский | LILACS | ID: biblio-1567965

Реферат

Advances in the treatment of critically ill patients have led to increased survival rates. However, survivors often experience significant consequences associated with the conventional model of care, in which patients tend to remain inactive, particularly during treatment with mechanical ventilation (MV) and prolonged use of sedation. This can result in mental, psychological, speech and swallowing disorders, and/or physical sequelae, including muscle weakness and consequent physical disability, which in many cases persist after discharge. Current evidence suggests that neuromuscular electrical stimulation has a positive effect on the mass and strength of the stimulated muscles, and may also induce systemic pro-myogenic, anti-inflammatory and regenerative effects, which could influence a decrease in MV time among other benefits. These effects could impact outcomes relevant to decision-makers, such as reduced intensive care unit length of stay and total hospitalization time.


Los avances en el tratamiento de pacientes críticamente enfermos han llevado a una mayor tasa de supervivencia. Sin embargo, los sobrevivientes a menudo experimentan consecuencias significativas asociadas al modelo convencional de atención, en el cual los pacientes tienden a permanecer inactivos, particularmente durante el tratamiento con ventilación mecánica (VM) y uso prolongado de sedación. Esto puede determinar trastornos mentales, psicológicos, del habla y deglución, y/o secuelas físicas, entre las que destacan la debilidad muscular y la consecuente discapacidad física, la que en muchos casos persisten tras el alta. La evidencia actual sugiere que la estimulación eléctrica neuromuscular tiene un efecto positivo sobre la masa y fuerza de los músculos estimulados, pudiendo además inducir efectos sistémicos promiogénicos, antiinflamatorios y regenerativos, que podrían influir en una disminución del tiempo de VM entre otros beneficios. Estos efectos podrían impactar desenlaces relevantes para los tomadores de decisiones, como la disminución de la estadía en unidades de cuidados intensivos y el tiempo de hospitalización total.


Тема - темы
Humans , Electric Stimulation Therapy/methods , Muscle Weakness/therapy , Critical Care , Intensive Care Units
5.
Einstein (Säo Paulo) ; 12(3): 361-365, Jul-Sep/2014. tab, graf
Статья в английский | LILACS | ID: lil-723924

Реферат

Objective To analyze the outcomes enabled by the neuromuscular electric stimulation in critically ill patients in intensive care unit assisted. Methods A systematic review of the literature by means of clinical trials published between 2002 and 2012 in the databases LILACS, SciELO, MEDLINE and PEDro using the descriptors “intensive care unit”, “physical therapy”, “physiotherapy”, “electric stimulation” and “randomized controlled trials”. Results We included four trials. The sample size varied between 8 to 33 individuals of both genders, with ages ranging between 52 and 79 years, undergoing invasive mechanical ventilation. Of the articles analyzed, three showed significant benefits of neuromuscular electrical stimulation in critically ill patients, such as improvement in peripheral muscle strength, exercise capacity, functionality, or loss of thickness of the muscle layer. Conclusion The application of neuromuscular electrical stimulation promotes a beneficial response in critically patients in intensive care. .


Objetivo Analisar os desfechos propiciados pela estimulação elétrica neuromuscular em pacientes graves assistidos em unidade de terapia intensiva. Métodos Revisão sistemática da literatura, por meio de ensaios clínicos publicados entre 2002 e 2012 nas bases de dados LILACS, SciELO, MedLine e PEDro, usando os descritores “intensive care unit”, “physical therapy”, “physiotherapy”, “electric stimulation” e “randomized controlled trials”. Resultados Foram incluídos quatro ensaios clínicos. O tamanho amostral variou entre 8 a 33 sujeitos, de ambos os gêneros, com média de idade variando entre 52 e 79 anos, submetidos à ventilação mecânica invasiva. Dos artigos analisados, três indicaram benefícios significativos da estimulação elétrica neuromuscular em pacientes graves, como melhora na força muscular periférica, capacidade de exercício, funcionalidade ou espessura de perda da camada muscular. Conclusão A aplicação de estimulação elétrica neuromuscular promove uma resposta benéfica em pacientes graves em terapia intensiva. Objective To analyze the outcomes enabled by the neuromuscular electric stimulation in critically ill patients in intensive care unit assisted. Methods A systematic review of the literature by means of clinical trials published between 2002 and 2012 in the databases LILACS, SciELO, MEDLINE and PEDro using the descriptors “intensive care unit”, “physical therapy”, “physiotherapy”, “electric stimulation” and “randomized controlled trials”. Results We included four trials. The sample size varied between 8 to 33 individuals of both genders, with ages ranging between 52 and 79 years, undergoing invasive mechanical ventilation. Of the articles ...


Тема - темы
Aged , Female , Humans , Male , Middle Aged , Critical Illness/therapy , Electric Stimulation Therapy/methods , Intensive Care Units , Muscle Weakness/therapy , Length of Stay , Randomized Controlled Trials as Topic , Time Factors , Treatment Outcome
6.
ABCD (São Paulo, Impr.) ; 25(2): 125-128, abr.-jun. 2012.
Статья в португальский | LILACS | ID: lil-663878

Реферат

INTRODUÇÃO - A flacidez muscular surge com maior frequência nas mulheres, o que causa fator ruim para a estética corporal. OBJETIVO - Analisar os resultados da corrente russa no fortalecimento da musculatura abdominal. MÉTODOS - Revisão bibliográfica com base nas publicações acessíveis pelas seguintes bases de dados: Medline/Pubmed, Scielo, Lilacs com cruzamento dos descritores corrente russa, flacidez, abdômen. O uso da eletroestimulação age tanto sobre as fibras brancas, que respondem pela velocidade, como também sobre as fibras vermelhas dado à sua sustentação, e ainda sobre as fibras intermediárias. CONCLUSÃO - Os dados publicados mostram a satisfação e êxito do tratamento, enfatizando que a corrente russa favorece o aumento da hipertrofia e força muscular.


INTRODUCTION - Muscle weakness appears most often in women, the factor that causes bad esthetics. OBJECTIVE - To analyze the results of the Russian current strengthening the abdominal muscles. METHODS - Literature review based on publications available in the following databases: Medline / Pubmed, Scielo, Lilacs with crossing headings Russian current, sagging, abdomen. The use of electrical stimulation acts both on the white fibers, which account for the speed, but also on the red fibers given their support, and on intermediate fibers. CONCLUSION - The data published show the satisfaction and success of treatment, emphasizing that the Russian current promotes increase of muscle strength and hypertrophy.


Тема - темы
Female , Humans , Abdominal Muscles , Electric Stimulation Therapy/methods , Muscle Strength , Muscle Weakness/therapy
8.
J. bras. pneumol ; 32(2): 161-171, mar.-abr. 2006. ilus
Статья в португальский | LILACS | ID: lil-433220

Реферат

A doença pulmonar obstrutiva crônica é progressiva e está relacionada a uma resposta inflamatória anormal dos pulmões à inalação de partículas e/ou gases tóxicos, sobretudo a fumaça de cigarro. Embora acometa primariamente os pulmões, diversas manifestações extrapulmonares relacionadas a esta enfermidade têm sido descritas. O aumento do número de células inflamatórias, que resulta em produção anormal de citocinas pró-inflamatórias, e o desequilíbrio entre a formação de radicais livres e a capacidade antioxidante, resultando em sobrecarga oxidativa, provavelmente são mecanismos envolvidos na inflamação local e sistêmica. Além disso, a diminuição do condicionamento físico secundária às limitações ventilatórias pode estar envolvida no desenvolvimento de alterações musculares. A doença pulmonar obstrutiva crônica apresenta diversas manifestações sistêmicas que incluem a depleção nutricional, a disfunção dos músculos esqueléticos, que contribui para a intolerância ao exercício, e as manifestações relacionadas a co-morbidades comumente observadas nestes pacientes. Essas manifestações têm sido relacionadas à sobrevida e ao estado geral de saúde dos pacientes. Nesse sentido, esta revisão tem como objetivo discutir os achados da literatura relacionados às manifestações sistêmicas da doença pulmonar obstrutiva crônica, ressaltando o papel da inflação sistêmica, e algumas perspectivas de tratamento.


Тема - темы
Humans , Cytokines/immunology , Inflammation/physiopathology , Muscle, Skeletal/physiopathology , Nutrition Disorders/physiopathology , Pulmonary Disease, Chronic Obstructive/physiopathology , Exercise Tolerance/physiology , Inflammation/etiology , Inflammation/immunology , Inflammation/therapy , Muscle Strength/physiology , Muscle Weakness/etiology , Muscle Weakness/immunology , Muscle Weakness/physiopathology , Muscle Weakness/therapy , Nutrition Disorders/etiology , Nutrition Disorders/immunology , Nutrition Disorders/therapy , Oxidative Stress/physiology , Pulmonary Disease, Chronic Obstructive/complications , Pulmonary Disease, Chronic Obstructive/immunology
9.
Rev. bras. med. esporte ; 10(4): 331-338, jul.-ago. 2004.
Статья в португальский, английский | LILACS | ID: lil-387128

Реферат

Há algum tempo o condicionamento físico vem sendo parte obrigatória no tratamento de portadores de DPOC. Estes pacientes apresentam comumente intolerância ao exercício de intensidade variável e relacionada à disfunção muscular esquelética. Neste sentido, o exercício físico apresenta-se como ramo mais importante no processo de reabilitação pulmonar. O exercício aeróbio e o treino de força com pesos são fundamentais no incremento de capacidade física e qualidade de vida, principalmente naqueles indivíduos que apresentam as formas moderada ou grave da DPOC. Além disso, espera-se atualmente maior desenvolvimento nas pesquisas em relação à aplicação de estimulação elétrica neuromuscular (EENM) e ao uso criterioso de substâncias ergogênicas tais como esteróides anabolizantes e creatina oral. Tendo em vista as repercussões negativas da disfunção muscular e a importância da reabilitação pulmonar no tratamento da DPOC, esta revisão tem como objetivo reunir informações de estudos relevantes acerca das principais estratégias para o recondicionamento muscular esquelético nestes pacientes nos últimos 15 anos.


Тема - темы
Humans , Androgens/therapeutic use , Creatine/therapeutic use , Muscle Weakness/therapy , Electric Stimulation Therapy , Lung Diseases, Obstructive/rehabilitation , Exercise Therapy/methods , Weight Lifting
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