摘要
We analyzed the clinical and biochemical characteristics of Japanese encephalitis(JE),based on acute meningeal and encephalitis syndrome(AMES)surveillancein Baoji from 2013 to 2021.We established the AMES program in Baoji and de-veloped surveillance according to the case definition.JE virus IgM antibody tests were conducted.Positive cases were divided in-to a probable JE and non-probable JE group according to the initial diagnosis.Clinical manifestations and biochemical character-istics of cerebrospinal fluid were compared between groups.The difference in JE incidence in the Baoji area and Shaanxiprovince before and after the AMES program was compared.Among 2 636 AMES cases reported during 2013-2021,the positive rate of JE virus IgM antibody was 5.99％,of which 86 cases(54.43％)lacked an initial JE diagnosis.The proportion of patients with fever,perturbed consciousness,neck rigidity,or meningeal irritation was significantly higher in the group with than without an initial JE diagnosis(P＜0.05).Biochemical tests indicated that the differences in cerebrospinal fluid color,white blood cell count,and chloride and glucose levels in the two groups were not statistically significant(P＞0.05).Cases of JE in Baoji from 2005 to 2012 accounted for 10.65％(134/1258)vs 16.58％(161/971).This study indicated that the AMES surveillance pro-gram increased the detection of JE and has aided in JE diagnosis.Thus,AMES surveillance should be enhanced.