摘要
Sebaceous neoplasms are rare adnexal tumors that can present a challenge to clinicians. Only four cases of sebaceous carcinoma with sebaceoma have been reported in the literature. Herein, we describe the case of a sebaceous carcinoma originating from a sebaceoma in a solitary nodule of the posterior neck. Immunohistochemically, the tumor cells were strongly positive for epithelial membrane antigen and p53. It is possible that adnexal carcinomas may arise from malignant transformation of their benign counterparts as well as de novo. Malignant transformation was likely in this case because the lesion was composed of distinct benign and malignant components, and the benign component showed the typical histopathological features of sebaceoma. This case underscores the fact that partial and superficial biopsies sometimes may not provide the correct diagnosis. If a surgeon suspects malignancy based on a clinical examination, then it is mandatory to perform a deep biopsy.
摘要
Sebaceous neoplasms are rare adnexal tumors that can present a challenge to clinicians. Only four cases of sebaceous carcinoma with sebaceoma have been reported in the literature. Herein, we describe the case of a sebaceous carcinoma originating from a sebaceoma in a solitary nodule of the posterior neck. Immunohistochemically, the tumor cells were strongly positive for epithelial membrane antigen and p53. It is possible that adnexal carcinomas may arise from malignant transformation of their benign counterparts as well as de novo. Malignant transformation was likely in this case because the lesion was composed of distinct benign and malignant components, and the benign component showed the typical histopathological features of sebaceoma. This case underscores the fact that partial and superficial biopsies sometimes may not provide the correct diagnosis. If a surgeon suspects malignancy based on a clinical examination, then it is mandatory to perform a deep biopsy.
摘要
BACKGROUND: Postpartum telogen effluvium refers to a phenomenon in which some hair in the growth phase progresses rapidly to the resting phase, which leads to excessive hair loss. This causes a high level of psychological stress. Therefore, an increasing number of women are seeking treatment for this condition. METHODS: The subjects of this study were postpartum women in the age range of 20 to 40 years who visited a university hospital between June 2015 and May 2016. Seven patients out of a total of 25 subjects were excluded, and their final follow-up visits were not performed because they found it difficult to return for the follow-up. After screening before delivery, the subjects were provided with hair care products. They visited the hospital 1 week, 1 month, and 3 months after giving birth. During each visit, the hair density and thickness were measured by photographing with a camera and using Folliscope® (Aram Huvis Corporation, Seoul, Korea). RESULTS: The hair thickness at the V-point improved from 0.089 µm at the baseline to 0.094 µm after using the shampoo for 3 months (P=0.028), and the hair density at the P-point increased significantly, from 75.24/cm² at the baseline to 81.33/cm² after using the shampoo for 3 months (P<0.001). CONCLUSIONS: In this study, a shampoo and a tonic in which the main material was horse placental growth factor combined with various materials, such as pumpkin extract, panthenol, and niacinamide, were clinically applied.
Subject(s)
Female , Humans , Alopecia , Cucurbita , Follow-Up Studies , Resting Phase, Cell Cycle , Hair , Horses , Mass Screening , Niacinamide , Parturition , Postpartum Period , Seoul , Stress, Psychological摘要
BACKGROUND: Postpartum telogen effluvium refers to a phenomenon in which some hair in the growth phase progresses rapidly to the resting phase, which leads to excessive hair loss. This causes a high level of psychological stress. Therefore, an increasing number of women are seeking treatment for this condition. METHODS: The subjects of this study were postpartum women in the age range of 20 to 40 years who visited a university hospital between June 2015 and May 2016. Seven patients out of a total of 25 subjects were excluded, and their final follow-up visits were not performed because they found it difficult to return for the follow-up. After screening before delivery, the subjects were provided with hair care products. They visited the hospital 1 week, 1 month, and 3 months after giving birth. During each visit, the hair density and thickness were measured by photographing with a camera and using Folliscope® (Aram Huvis Corporation, Seoul, Korea). RESULTS: The hair thickness at the V-point improved from 0.089 µm at the baseline to 0.094 µm after using the shampoo for 3 months (P=0.028), and the hair density at the P-point increased significantly, from 75.24/cm² at the baseline to 81.33/cm² after using the shampoo for 3 months (P<0.001). CONCLUSIONS: In this study, a shampoo and a tonic in which the main material was horse placental growth factor combined with various materials, such as pumpkin extract, panthenol, and niacinamide, were clinically applied.