摘要
Transscleral diode laser retinopexy and cryoretinopexy were performed in pigmented rabbits, and light and electron microscopic, and immunohistochemical studies were done. Acute lesions produced by cryoretinopexy showed significant retinal destruction and, in contrast, those produced by transscleral diode laser showed reaction limited to the outer retina and choroid. Chronic lesions by cryoretinopexy showed marked retinal thinning and chorioretinal adhesions. Pigment-laden cells were aggregated at the level of the retinal pigment epithelium, with some having migrated into the sensory retina. The laser lesions showed similar findings but less in size and severity. Acute lesions showed absence of reactivity with all antibodies. While marked expressions of GFAP, vimentin, and S-100 epitopes were seen in chorioretinal scar tissues made with cryoretinopexy, expressions with less intensity were seen with diode retinopexy. Migrating pigment-laden cells were labelled positive for cytokeratins and few cells were positive for anti-macrophage antibody. These results suggest that although transscleral diode laser induce less inner retinal destruction and more localized burns than cryoretinopexy, both forms of treatment produce similar deep retinal Muller cell reaction, as demonstrated by the immunohistochemical studies.
Subject(s)
Rabbits , Antibodies , Burns , Choroid , Cicatrix , Epitopes , Keratins , Lasers, Semiconductor , Retina , Retinal Pigment Epithelium , Retinaldehyde , Vimentin摘要
A case of painful ophthalmoplegia with unilateral ocular pain, fixed eyeball to all directions of gaze, and loss of vision is presented. After intensive steroid therapy, conjunctival chemosis subsided markedly, but no improvement was seen in other clinical signs. We took a CT scan of orbit brain and performed nasopharyngeal biopsy and open biopsy through craniectomy. Based on the results of clinical features and findings of the CT scan and tissues, we diagnosed painful ophthalmoplegia secondary to nasopharyngeal carcinoma metastasized to orbital apex and brain.
Subject(s)
Female , Humans , Middle Aged , Brain Neoplasms/pathology , Carcinoma, Squamous Cell/complications , Nasopharyngeal Neoplasms/complications , Ophthalmoplegia/etiology , Orbital Neoplasms/pathology , Pain/etiology摘要
Eighty children who had horizontal strabismus were examined with Titmus and random-dot stereogram(TNO) for the stereoacuity. The patients were analyzed about visual acuity and types of strabismus. In addition, we also analyzed thirty three patients who received correction surgery for the strabismus for evaluation of the changes of postoperative visual acuity and its relationship to the stereoacuity. The results were as follows: 1. The stereoacuity tested by the TNO was proportional to the change of visual acuity, but that of the Titmus was not proportional. 2. The stereoacuity in the exodeviation was higher than the esodeviation. The stereoacuity in the intermittent exotropia was higher than the constant exotropia, and there was no difference in stereoacuity between the accommodative and nonaccommodative esotropia. 3. The visual acuity was improved postoperatively. 4. The postoperative stereoacuity was also improved. The patients with esodeviation showed more improvement in the stereoacuity compared with that of the patients with exodeviation.