1.
Journal of Forensic Medicine
; (6): 169-170, 2005.
文章
在 中文
| WPRIM
| ID: wpr-983099
摘要
OBJECTIVE@#To establish an anaphylactic shock model induced by human mixed serum in guinea pigs.@*METHODS@#Eighteen guinea pigs were divided into two groups: sensitized and control, The sensitized group were immunized intracutaneously with human mixed serum and then induced by endocardiac injection after 3 weeks.@*RESULTS@#Symptoms of anaphylactic shock appeared in the sensitized group. The level of serum IgE were increased in the sensitized group significantly.@*CONCLUSIONS@#An animal model of anaphylactic shock wer established successfully. It provide a tool for both forensic study and anaphylactic shock therapy.