摘要
Abstract Two new monoterpene glycosides, perillanolides A and B, together with a known compound reported from the genus Perilla for the first time were isolated and characterized from the leaves of Perilla frutescens (L.) Britton, Lamiaceae, a garnish and colorant for foods as well as commonly used for traditional medicine. The structures of the isolated compounds were elucidated on the basis of extensive spectroscopic evidences derived from nuclear magnetic resonance experiments, mass spectrometry and by comparing their physical and spectroscopic data of literature. These compounds, together with the previously isolated secondary metabolites of this species, were investigated for their inhibitory effects on xanthine oxidase in vitro. Of the compounds, luteolin showed the strongest inhibitory activity with an IC50 value of 2.18 µM. Esculetin and scutellarein moderately inhibited the enzyme, while perillanolides A and B, and 4-(3,4-dihydroxybenzoyloxymethyl)phenyl-O-β-D-glucopyranoside exerted weak activities.
摘要
A new stereoisomeric monoterpene glycoside and five already-known compounds were isolated from the n-BuOH soluble fraction of Clematis heracleifolia leaves. On the basis of spectral data, the structures of the isolated compounds were identified as protocatechuic acid (1), ferulic acid (2), caffeic acid (3), aesculin (4), (6Z)-9-hydroxylinaloyl glucoside (5), and 9-hydroxylinaloyl glucoside (6) and these were isolated for the first time from this plant. Among these compounds, (6Z)-9-hydroxylinaloyl glucoside (5) is a newly isolated from plant source.
Subject(s)
Clematis , Esculin , Plants , Stereoisomerism摘要
OBJECTIVE: To study the chemical constituents from the seed cake of Paeonia ostii. METHODS: Chemical constituents were isolated by Sephadex LH-20, preparative HPLC, and silica gel column chromatography. The structures were elucidated on the basis of spectral data analysis. RESULTS: Three compounds, 4, 9-dihydroxy-8, 10-dehydrothymol-1-O-β-Z)-glucoside(1), 6′-O-β-Z)-glucopyranosylalbiflorin(2), and paeonidanin(3), were isolated from the seed cake of P. ostii. CONCLUSION: Compound 1 is a new compound, and compounds 2 and 3 were isolated from the seed cake of P. ostii for the first time.