摘要
Introduction: Melanomas are malignant neoplasms that occur in various anatomical sites, including the eye. Ocular melanomas account for 5% of all melanomas and are mainly described in Caucasian and older individuals. This study describes the clinical and pathological characteristics of uveal (choroid) melanoma in a Caucasian patient. Case report: A 41-year-old Caucasian female patient, brown eyes, without history of ophthalmological diseases or family history of cancer experienced pain and loss of visual acuity in the left eye. On clinical examination, an increase of ocular pressure was detected. Ultrasound showed a mushroom-like neoformation. Moreover, magnetic resonance imaging showed a mass with spontaneous hypersignal on T1-weighted images, intense gadolinium enhancement, and marked hyposignal on T2-weighted images. The patient was referred to the Oncology Ophthalmology department for enucleation due to suspected uveal melanoma. Anatomopathological analysis revealed a blackened mass in the eyeball. Histologically, the mass comprised spindle cells (50%) and epithelioid cells (50%). A diagnosis of choroidal melanoma was established based on the identification of ophthalmoscopic, imaging, and histological characteristics of the tumor. Conclusion: Choroidal melanomas usually occur in males, clear-eyed, and older individuals. A wide variety of ocular lesions may mimic choroidal melanoma, which should be included in the differential diagnosis of choroidal nevus and peripheral hemorrhages
Introdução: Melanomas são neoplasias malignas que ocorrem em vários sítios anatômicos, incluindo o olho. Os melanomas oculares correspondem a 5% de todos os melanomas e são descritos principalmente em indivíduos caucasianos e idosos. Este estudo descreve as características clinicopatológicas de um caso de melanoma uveal (coroide) em um paciente caucasiano. Relato do caso: Paciente, sexo feminino, 41 anos, caucasiana, olhos castanhos, sem antecedentes de doenças oftalmológicas e sem história familiar de câncer, com queixa de dor e perda da acuidade visual no olho esquerdo. No exame clínico, observou-se aumento da pressão ocular. O ultrassom revelou neoformação com aspecto de cogumelo, e a ressonância magnética, massa com hipersinal espontâneo em T1, intenso realce pelo gadolínio e marcado hipossinal em T2. A paciente foi encaminhada para cirurgia de enucleação em razão da suspeita de melanoma uveal. Foi realizada análise anatomopatológica que evidenciou massa enegrecida no interior do globo ocular. Histologicamente, a massa era constituída por 50% de células fusiformes e 50% de células epitelioides. O diagnóstico de melanoma de coroide baseou-se nas características oftalmoscópicas, imaginológicas e histológicas do tumor. Conclusão: Melanomas de coroide geralmente ocorrem em pacientes do sexo masculino, de olhos claros e idosos. Alerta-se que uma grande variedade de lesões oculares pode se assemelhar ao melanoma de coroide e este deve ser considerado no diagnóstico diferencial de nevo de coroide e hemorragias periféricas
Introducción: Los melanomas son neoplasias malignas que se presentan en varios sitios anatómicos, incluido el ojo. Los melanomas oculares representan el 5% de todos los melanomas y se describen principalmente en individuos caucásicos y de mayor edad. Este estudio describe las características clínicas y patológicas del melanoma uveal (coroides) en un paciente caucásico. Informe del caso: Paciente femenino de 41 años, caucásica, ojos marrones, sin antecedentes de enfermedades oftalmológicas y sin antecedentes familiares de cáncer, que consulta por dolor y pérdida de agudeza visual en el ojo izquierdo. En el examen clínico se observó aumento de la presión ocular. La ecografía mostró una neoformación con aspecto de hongo y la resonancia magnética mostró una masa con hiperseñal espontánea en T1, realce intenso de gadolinio y marcada hiposeñal en T2. La paciente fue remitida para cirugía de enucleación por sospecha de melanoma uveal. Se realizó análisis anatomopatológico, el cual mostró una masa ennegrecida en el interior del globo ocular. Histológicamente, la masa constaba de un 50 % de células fusiformes y un 50 % de células epitelioides. El diagnóstico de melanoma de coroides se basó en las características oftalmoscópicas, imagenológicas e histológicas del tumor. Conclusión: Los melanomas coroideos generalmente ocurren en pacientes masculinos, de ojos claros y de edad avanzada. Se advierte que una amplia variedad de lesiones oculares puede asemejarse al melanoma coroideo, y esto debe incluirse en el diagnóstico diferencial de nevus coroideo y hemorragias periféricas
Subject(s)
Humans , Female , Eye Enucleation , Choroid Neoplasms , Eye Pain , Melanoma摘要
El síndrome de Tolosa-Hunt es una entidad poco frecuente cuya etiopatogenia y mecanismos fi- siopatológicos son controversiales, se caracteri- za por cefalea asociada a parálisis de uno o más nervios craneales, diplopía, estrabismo y ptosis palpebral, ocasionados por el compromiso del seno cavernoso o la fisura orbitaria superior. Su diagnóstico es un reto y se aborda dentro de los diagnósticos diferenciales de las oftalmoplejías dolorosas. Con el objetivo de describir y actua- lizar el conocimiento sobre esta enfermedad se presenta el caso de una paciente de 14 años que acudió a consulta por cefalea intensa, dolor ocu- lar y afección de nervios craneales. Los hallazgos clínicos y la resonancia magnética confirmaron el diagnóstico del síndrome de Tolosa Hunt...(AU)
Subject(s)
Humans , Female , Adolescent , Cavernous Sinus , Tolosa-Hunt Syndrome/diagnosis , Ophthalmology , Diplopia/complications , Eye Pain摘要
Masculino de 71 años, hipertenso, con tabaquismo activo (IPA 51); ingresó a urgencias por disminución progresiva de la agudeza visual bilateral hasta llegar a amaurosis bilateral, no dolor ocular. Asociado a cefalea crónica frontal bilateral, pulsátil. RNM cerebral mostró engrosamiento difuso de la meninge en relación con paquimeningitis. Biopsia de meninge mostró paquimeninge. Se descartaron casusas neoplásicas, infecciosas, autoinmunes, por lo cual se consideró una paquimeningitis hipertrófica idiopática (PHI). La paquimeningitis hipertrófica es una entidad clínica rara caracterizada por engrosamiento localizado o difuso de la duramadre, con o sin una inflamación asociada, produce déficit neurológico progresivo por compresión de las estructuras adyacentes (1). El dolor de cabeza es el síntoma inicial más común, seguido de síntomas oftalmológicos, como pérdida visual y diplopía (2). Su etiología es multifactorial, en estudios de imagen se encuentra engrosamiento dural en la fosa craneal posterior (2), imitando la torre Eiffel iluminada en noche (signo de Eiffel de noche) (3).
A 71-year-old hypertensive male who was an active smoker (IPA 51) was admitted to the emergency room due to progressively decreasing bilateral eyesight to the point of bilateral amaurosis, without ocular pain. This was associated with a chronic bilateral pulsatile frontal headache. A brain NMR showed diffuse meningeal thickening related to pachymeningitis. A meningeal biopsy showed pachymeninge. Neoplastic, infectious and autoimmune causes were ruled out; therefore, it was considered to be idiopathic hypertrophic pachymeningitis (IHP). Hypertrophic pachymeningitis is a rare clinical entity characterized by localized or diffuse thickening of the dura mater, with or without associated inflammation. It causes progressive neurological deficit due to compression of the adjacent structures (1). Headache is the most common initial symptom, followed by ophthalmological symp-toms such as vision loss and diplopia (2). Its etiology is multifactorial. Dural thickening in the posterior cranial fossa, mimicking the Eiffel Tower illuminated at night (Eiffel-by-night sign), is found on imaging studies. References 1. Uchida H, Ogawa Y, Tominaga T. Marked effectiveness of low-dose oral methotrexate for steroid-resistant idiopathic hypertrophic pachymeningitis: Case report. Clin Neurol Neurosurg. 2018 May;168:303. 2. Hahn LD, Fulbright R, Baehring JM. Hypertrophic pachymeningitis. J Neurol Sci. 2016 Aug;367:27883. 3. Dash GK, Thomas B, Nair M, Radhakrishnan A. Clinico-radiological spectrum and outcome in idiopathic hypertrophic pachymeningitis. J Neurol Sci. 2015 Mar;350(12):5160. Figure 1. A: Brain NRM with gadolinium, coronal view. Diffuse meningeal thickening, mainly on the right, with significant enhancement on diffuse gadolinium application, compatible with pachymeningitis. B: Orbital NRM with gadolinium. Diffuse pachymeningitis changes which reach the left and right orbital fissures. Figure 2. Meningeal biopsy (H&E 40X). Fibroconnective tissue can be seen, with fibroblast proliferation, increased collagen, cal-cifications and mononuclear inflammatory infiltrate throughout its thickness, compatible with pachymeninge.
Subject(s)
Humans , Female , Aged , Visual Acuity , Meningitis , Vision, Ocular , Biopsy , Cranial Fossa, Posterior , Diplopia , Eye Pain , Headache摘要
ABSTRACT Objective: The objective was to evaluate the efficacy of gabapentin in the management of neuropathic pain in patients with keratoconus, who were treated with fast (10 minutes) epi-off corneal crosslinking (CXL). Methods: This was a prospective, double-blind, randomized study. The sample comprised patients with bilateral progressive keratoconus, aged 12 years or older, who underwent a bilateral epi-off corneal CXL (fast - 10 minutes) procedure. One group was given placebo orally, and the other group received gabapentin 600 mg orally, both preoperatively. The visual analogue scale (VAS) was applied to record postoperative pain up to 48 hours after procedure. The study was conducted at the Belotto Stock Centro Oftalmológico, in the city of Joaçaba, Santa Catarina, Brazil, from June 2018 to September 2019. Results: At no point in the study significant differences were observed between groups, in terms of pain intensity measured by means of the VAS questionnaire, or of opioid use (Paco®), though opioid consumption was 21% lower in the group receiving gabapentin. Conclusion: We concluded gabapentin has no efficacy in postoperative pain control after epi-off corneal CXL (fast - 10 minutes). Although there was no statistically significant difference, the group that received gabapentin suffered less pain, resulting in lower opioid consumption. UTN number: U1111-1256-0330.
RESUMO Objetivo: Avaliar a eficácia do uso da gabapentina no manejo da dor neuropática em pacientes portadores de ceratocone submetidos ao tratamento de crosslinking corneano epi-off fast de 10 minutos. Métodos: Tratou-se de pesquisa prospectiva, duplo-cega, randomizada. A amostra foi composta de pacientes com ceratocone progressivo bilateral, a partir dos 12 anos de idade, submetidos ao procedimento de crosslinking corneano acelerado epi-off fast de 10 minutos bilateral. Um grupo recebeu placebo via oral e o outro, gabapentina 600mg, via oral, ambos no pré-operatório. A Escala Visual Analógica foi aplicada para registrar a dor pós-operatória até 48 horas após o procedimento. A pesquisa foi realizada no período de junho de 2018 a setembro de 2019 em um centro oftalmológico. Resultados: Não foram observadas diferenças estatísticas significativas para ambos os grupos, tanto na intensidade da dor medida pela Escala Visual Analógica, como na redução do uso do opioide (Paco®), em qualquer horário analisado durante um período de 48 horas. No entanto, houve redução de 21% no consumo de opioides pelo grupo que fez uso da gabapentina. Conclusão: A gabapentina não demonstrou eficácia no controle da dor no pós-operatório do crosslinking corneano epi-off fast de 10 minutos. No entanto, observou-se que, mesmo não havendo diferença estatisticamente significativa, houve diminuição da dor no grupo em que foi usada a gabapentina, resultando na redução do consumo de opioides. Número UTN: U1111-1256-0330.
Subject(s)
Humans , Male , Female , Adolescent , Adult , Pain, Postoperative/drug therapy , Cross-Linking Reagents/therapeutic use , Keratoconus/therapy , Riboflavin/therapeutic use , Ultraviolet Rays , Pain Measurement , Double-Blind Method , Administration, Oral , Prospective Studies , Surveys and Questionnaires , Collagen/metabolism , Photosensitizing Agents/therapeutic use , Cornea/metabolism , Eye Pain/drug therapy , Gabapentin/administration & dosage , Gabapentin/therapeutic use , Analgesics/therapeutic use摘要
ABSTRACT Description of a patient with Fuchs endothelial dystrophy submitted to a corneal transplant, performed by Descemet membrane endothelial keratoplasty, which evolved with sudden, paroxysmal pain in the frontotemporal region, postoperatively. Due to the ophthalmologic picture of the patient, the attending physician believed in possible rejection of the graft, neglecting the complaint of pain. Even after a successful second transplant, performed due to primary failure, disabling pain persisted and the physician did not manage it. After years of investigation, consulting with several specialists, it was concluded the patient presented trigeminal neuralgia that had not been treated since the surgical procedure. In addition, it led to several psychosocial consequences. Therefore, it is essential to be aware trigeminal neuralgia is a possible outcome of corneal transplantation, and its symptoms should not be neglected by the attending physician, thus contributing to better management for transplanted patients.
RESUMO Descrição do relato de caso de uma paciente com distrofia endotelial de Fuchs submetida a transplante de córnea, realizado pela técnica DMEK, que evoluiu com quadro de dor súbita, paroxística, em região frontotemporal, no pós-operatório. Devido ao quadro oftalmológico da paciente, o médico assistente acreditava em possível rejeição do enxerto, negligenciando a dor. Mesmo após sucesso do segundo transplante, realizado devido à falência primária, as dores incapacitantes persistiam, e nenhuma conduta, por parte do médico, foi realizada. Após anos de investigação, mediante consultas com diversos especialistas, concluiu-se que a paciente apresentava um quadro de neuralgia do nervo trigêmeo que não tinha sido tratada desde a realização do procedimento cirúrgico. Além disso, apresentava uma série de consequências psicossociais. Portanto, torna-se imprescindível entender que a neuralgia do nervo trigêmeo é um possível desfecho do transplante de córnea, e seus sintomas não devem ser negligenciados por parte do médico assistente, contribuindo para melhores condutas para os pacientes transplantados.
Subject(s)
Humans , Female , Middle Aged , Corneal Transplantation/adverse effects , Pain, Postoperative/etiology , Trigeminal Neuralgia/etiology , Trigeminal Neuralgia/drug therapy , Fuchs' Endothelial Dystrophy/surgery , Corneal Transplantation/methods , Descemet Membrane/surgery , Descemet Stripping Endothelial Keratoplasty/adverse effects , Descemet Stripping Endothelial Keratoplasty/methods , Eye Pain/etiology , Pain Management , Malpractice摘要
Resumo Objetivo: Avaliar a efetividade e o perfil de segurança da ciclofotocoagulação transescleral padrão (CTCTE) e sua variação técnica denominada slow cooking (CTCTE SC) em pacientes com olho cego doloroso por glaucoma neovascular. Métodos: Pacientes foram submetidos a exame oftalmológico, graduando o nível da dor através de escala gráfica/numérica e divididos em dois grupos, um para tratamento com CTCTE e outro CTCTE SC. O acompanhamento foi realizado no primeiro, trigésimo e nonagésimo dias. Resultados: Dos 26 pacientes inclusos, 11 (42,3%) eram do sexo masculino. A idade média dos pacientes foi de 69 anos. Destes, 16 pacientes foram submetidos ao tratamento CTCTE e 10 pacientes a CTCTE SC. A pressão intraocular (PIO) teve média pré tratamento de 49 ± 23 mmHg no grupo CFCTE e medias no 1º, 30º e 90º dias pós-operatórios respectivamente: 32 ± 24 mmHg, 38 ± 18 mmHg, 43 ± 10 mmHg. No grupo submetido a técnica CFCTE SC a PIO prévia foi 54 ± 16 mmHg e médias no 1º, 30º e 90º dias pós-operatórios respectivamente: 38 ± 22 mmHg, 39 ± 10 mmHg , 44 ± 09 mmHg. A redução da dor foi efetiva em 88,4% pacientes. Durante o pós-operatório foi verificado hiperemia, quemose e hifema. Não foram observadas complicações graves. Conclusão: O tratamento do olho cego doloroso com ciclofotocoagulação transescleral com baixa carga foi um procedimento seguro e eficaz na resolução da dor, mas apresentou um baixo nível de redução da pressão intraocular em ambas técnicas usadas.
Abstract Objective: To evaluate the effectiveness and safety profile of standard transescleral cyclophotocoagulation (CTCTE) and its technical variation of slow cooking (CTCTE SC) in patients with neovascular glaucoma pain. Methods: Patients underwent ophthalmological examination, grading their pain level through a graphical / numerical scale and divided into two groups, one for treatment with CTCTE and another CTCTE SC. Follow-up was performed on the first, thirtieth and ninetieth days. Results: Of the 26 patients included, 11 (42.3%) were male. The average age of the patients was 69 years. Of these, 16 patients underwent CTCTE treatment and 10 patients underwent CTCTE SC. Intraocular pressure (IOP) had a mean pre-treatment of 49 ± 23 mmHg in the CFCTE group and medians at the 1st, 30th and 90th postoperative days respectively: 32 ± 24 mmHg, 38 ± 18 mmHg, 43 ± 10 mmHg. In the group submitted to the CFCTE SC technique, the previous IOP was 54 ± 16 mmHg and averages on the 1st, 30th and 90th postoperative days respectively: 38 ± 22 mmHg, 39 ± 10 mmHg, 44 ± 09 mmHg. Pain reduction was effective in 88.4% patients. During the postoperative period, hyperemia, chemosis and hyphema were observed. No serious complications were observed. Conclusion: Painful blind eye treatment with low load transscleral cyclophotocoagulation was a safe and effective procedure for pain resolution, but presented a low level of intraocular pressure reduction in both techniques used.
Subject(s)
Humans , Male , Female , Aged , Glaucoma, Neovascular/surgery , Glaucoma, Neovascular/complications , Blindness/etiology , Laser Coagulation/methods , Eye Pain/surgery , Sclera/surgery , Prospective Studies , Lasers, Semiconductor/therapeutic use摘要
Resumo A síndrome de Marfan é uma doença de herança autossômica dominante e que afeta o tecido conjuntivo com manifestações fenotípicas que envolvem os sistemas esquelético, cardiovascular e ocular. As principais manifestações oculares são a subluxação do cristalino, a miopia e o descolamento da retina. O objetivo deste artigo foi relatar a conduta clínico-cirúrgica de um paciente portador da síndrome de Marfan com cristalino luxado para a cavidade vítrea e que evoluiu com severa reação facoanafilática caracterizada por um glaucoma secundário severo e descompensação corneana.
Abstract Marfan syndrome is an autosomal dominant inheritance disease that affects connective tissue with phenotypic manifestations involving the skeletal, cardiovascular and ocular systems. The main ocular manifestations are the subluxation of the lens, myopia and retinal detachment. The aim of this article was to report the clinical and surgical management of a patient with Marfan syndrome with luxated lens for the vitreous cavity and who developed a severe phacoanaphylactic reaction characterized by severe secondary glaucoma and corneal decompensation.
Subject(s)
Humans , Male , Middle Aged , Lens Subluxation/complications , Lens Subluxation/etiology , Anaphylaxis/etiology , Marfan Syndrome/complications , Vitrectomy/methods , Vitreous Body/surgery , Visual Acuity , Corneal Edema/etiology , Glaucoma/etiology , Lens Subluxation/surgery , Lens Subluxation/diagnosis , Vision, Low , Ultrasonography , Lens Implantation, Intraocular/methods , Eye Pain , Slit Lamp Microscopy , Intraocular Pressure摘要
Introducción: la catarata es la enfermedad ocular de mayor prevalencia, se estima que es la responsable del 38% de la ceguera en el mundo. Objetivo: describir las modificaciones de la presión intraocular en pacientes operados de catarata en la provincia de Pinar del Río durante el periodo entre abril de 2016 a febrero de 2018. Métodos: investigación, cuantitativa descriptiva, prospectiva y longitudinal en una muestra de 76 pacientes operados de catarata y dispuestos a participar en la investigación. Resultados: el 57 % de los pacientes estudiados fueron del sexo femenino y presentaron una presión intraocular media pre quirúrgica media de 16.92 mm de Hg y a los dos meses disminuyó a 13.69 mm de Hg. El 34 % de los pacientes pertenecieron al grupo de edades de 61-70 años. El 80% de los pacientes presentaron cataratas nucleares El 42 % de los pacientes tenían una agudeza visual mejor corregida mayor de 0.3. Conclusiones: el sexo femenino fue el más representado en cuanto a presión intraocular preoperatoria media, las edades más representadas fueron las avanzadas y la presión intraocular disminuyó en todos los pacientes tras la cirugía de catarata
Introduction: cataract is the ocular disease with the highest prevalence, it is estimated that it is responsible for 38% of blindness in the world. Objective: to describe the changes in intraocular pressure in cataract operated patients in the province of Pinar del Río during the period from April 2016 to February 2018. Methods: research, quantitative descriptive, prospective and longitudinal in a sample of 76 cataract operated patients willing to participate in the research. Results: 57% of the patients studied were female and they presented an average pre-surgical mean intraocular pressure of 16.92 mm Hg and at two months it decreased to 13.69 mm Hg. 34% of the patients belonged to the age group of 61-70 years. 80% of the patients presented nuclear cataracts. 42% of the patients had a better corrected visual acuity greater than 0.3. Conclusions: the female sex was the most represented in terms of mean preoperative intraocular pressure, the most represented ages were advanced, and the intraocular pressure decreased in all patients after cataract surgery
Subject(s)
Humans , Male , Female , Adult , Eye Abnormalities , Ocular Hypertension , Eye Diseases , Patients , Health of Specific Groups , Eye Pain摘要
Objetivo: Identificar marcadores potenciais para auxiliar na busca ativa de endoftalmite após cirurgia de catarata. Método: Estudo retrospectivo, descritivo e longitudinal, realizado por meio da revisão de prontuários de pacientes submetidos à cirurgia de catarata. Resultados: A amostra incluiu 20 pacientes (grupo de estudo GE) que desenvolveram endoftalmite pós-operatória e 309 pacientes (grupo controle GC) que não apresentaram endoftalmite. Os dados foram analisados para identificar os marcadores clínicos e epidemiológicos com uma diferença percentual ≥30% entre os grupos. Em comparação com o GC, o GE teve frequência ≥30% em: sinais e sintomas pós-operatórios definidos (dor, reação da câmara anterior, hipópio, edema da córnea, hiperemia conjuntival e opacidade vítrea); mais de 4 retornos pós-operatórios; e realização de injeção de antibiótico intravítreo. Conclusão: Os indicadores selecionados são sugeridos para incorporação na busca ativa das infecções pós-operatórias de endoftalmite, visando à facilidade operacional do sistema de vigilância epidemiológica
Objective: To identify potential markers to assist in the active search of endophthalmitis after cataract surgery. Method: Retrospective, descriptive, and longitudinal study, conducted through review of medical records of patients who underwent cataract surgery. Results: The sample included 20 patients (study group - SG) who developed postoperative endophthalmitis and 309 patients (control group - CG) who did not have endophthalmitis. The data were analyzed to identify the clinical and epidemiological markers with a percentage difference ≥30% between groups. In comparison with the CG, the SG demonstrated frequency ≥30% in established postoperative signs and symptoms (pain, anterior chamber reaction, hypopyon, corneal edema, conjunctival hyperemia, and vitreous opacity); more than four postoperative appointments; and administration of an intravitreal antibiotic injection. Conclusion: The selected markers are suggested for incorporation into the active search for post-operative endophthalmitis, in order to facilitate the operation of the epidemiological surveillance system
Objetivo: Identificar marcadores potenciales para auxiliar en la búsqueda activa de endoftalmitis tras cirugía de facectomía. Método: Estudio retrospectivo, descriptivo y longitudinal, realizado por medio de la revisión de prontuarios de pacientes sometidos a la cirugía de catarata. Resultados: La muestra incluyó 20 pacientes (grupo de estudio GE) que desarrollaron endoftalmitis pos-operatoria y 309 pacientes (grupo control GC) que no presentaron endoftalmitis. Los datos fueron analizados para identificar los marcadores clínicos y epidemiológicos con una diferencia porcentual ≥30% entre los grupos. En comparación con el GC, el GE tuvo frecuencia ≥30% en: señales y síntomas pos-operatorios definidos (dolor, reacción de la cámara anterior, hipopión, edema de la córnea, hiperemia conjuntival y opacidad vítrea); más de 4 retornos pos-operatorios; y realización de inyección de antibiótico intravítreo. Conclusión: Los indicadores seleccionados son sugeridos para incorporación en la búsqueda activa de las infecciones pos-operatorias de endoftalmitis, buscando la facilidad operacional del sistema de vigilancia epidemiológica
Subject(s)
Humans , Ophthalmologic Surgical Procedures , Eye Infections , Endophthalmitis , Eye Diseases , Postoperative Care , Vitreous Body , Corneal Edema , Eye Infections, Bacterial , Eye Pain , Epidemiological Monitoring , Hyperemia摘要
PURPOSE: We report short-term treatment effects of a mini-scleral lens in patients with Stevens-Johnson syndrome and corneal ectasia. CASE SUMMARY: A 54-year-old female who had been diagnosed with Stevens-Johnson syndrome and keratoconus presented with persistent right eye pain and decreased visual acuity. Therapeutic lenses, topical antibiotic eye drops, and topical steroid eye drops were used; however the symptoms were not controlled, then the patient was treated with a mini-scleral contact lens in the right eye. At the time of the first visit to our hospital 17 years ago, and the best-corrected visual acuity (BCVA) of the right eye was logMAR 0.22. However, Stevens-Johnson syndrome and corneal ectasia were severe and cataract surgery was considered because of worsening cataracts, but the patients refused this surgery. At the time, the BCVA of the right eye was then reduced to logMAR 1.10. On ophthalmic examination, there was conjunctival fibrosis and corneal neovascularization of the right eye. The symptoms were not managed with a using a therapeutic lens, and then the patient was prescribed a mini-scleral contact lens. After wearing the mini-scleral contact lens, the corneal and conjunctival neovascularization was reduced. After 6 months, the BCVA of the right eye improved to logMAR 0.60. CONCLUSIONS: In patients with Stevens-Johnson syndrome and corneal ecstasia, mini-scleral contact lens can be considered as a useful treatment option for visual improvement and symptom control.
Subject(s)
Female , Humans , Middle Aged , Cataract , Contact Lenses , Corneal Neovascularization , Dilatation, Pathologic , Eye Pain , Fibrosis , Keratoconus , Ophthalmic Solutions , Stevens-Johnson Syndrome , Visual Acuity摘要
PURPOSE: We report a rare case of isolated traumatic aniridia in a pseudophakic eye. CASE SUMMARY: A 69-year-old female came to our emergency department complaining of right eye pain and visual disturbance after trauma due to fall on the stairs. Five years earlier she had undergone an uncomplicated right sutureless phacoemulsification cataract extraction through a 2.2 mm temporal clear corneal incision, followed by insertion of a folding intracapsular intraocular lens. Total iris expulsion occurred through the cataract incision without extension of the wound or disruption of the posterior capsule or intraocular lens. CONCLUSIONS: We report a rare case of isolated traumatic aniridia in a pseudophakic eye, which has not been reported in the Republic of Korea.
Subject(s)
Aged , Female , Humans , Aniridia , Cataract , Cataract Extraction , Emergency Service, Hospital , Eye Pain , Iris , Lenses, Intraocular , Phacoemulsification , Republic of Korea , Wounds and Injuries摘要
OBJECTIVE: Uveitis is the most common extra-articular manifestation occurring in patients with ankylosing spondylitis (AS). This study examined the characteristics of uveitis in patients with AS using a questionnaire survey. METHODS: A questionnaire-based survey was given to patients enrolled in an AS registry at a rheumatology clinic in a tertiary hospital between September 2015 and December 2015. The patients responded to several questions and sub-questions related to uveitis. RESULTS: A total of 750 patients participated in the survey. The number of patients diagnosed with uveitis in the ophthalmology department was 218 (29%). The most common symptoms in patients with uveitis were ocular injection (61%), eye pain (54%), and decreased visual acuity (51%). Interestingly, 91 of the 532 patients (17%) who had not been diagnosed with uveitis before also experienced similar symptoms, such as tearing, ocular injection, and eye pain. The number of patients who experienced a flare of uveitis more than once a year was 109 (50%), and 124 patients with uveitis responded that the treatment of AS had no significant effect on the prevention of uveitis recurrence. CONCLUSION: The clinical characteristics of uveitis that patients experience was investigated through surveys. Because uveitis in patients with AS is not well diagnosed and treated, active screening for suspected symptoms and the prevention of a recurrence is needed.
Subject(s)
Humans , Eye Pain , Korea , Mass Screening , Ophthalmology , Recurrence , Rheumatology , Spondylitis, Ankylosing , Surveys and Questionnaires , Tears , Tertiary Care Centers , Uveitis , Visual Acuity摘要
PURPOSE: Bell palsy is an idiopathic peripheral facial nerve paralysis of sudden onset. Though the incidence in children is relatively lower than adult population, it is not uncommon. Because of its' relative rarity and good prognosis, there have been few studies about clinical features and courses of Bell palsy in pediatric population. The aim of our study was to report the clinical characteristics and practices of Bell palsy in children and adolescent in a single center. METHODS: We reviewed medical records of 70 patients diagnosed as Bell palsy in Daegu Catholic University Medical Center from September 2006 to June 2017 retrospectively. We included only first episode. RESULTS: Of the 70 patients, 35 was male, 35 was females. Median age was 102 months. There was no seasonal difference. Median duration of palsy was 3 days. The first symptoms were auricular pain (14%), facial palsy (83%), eye pain (1%), and dysguesia (1%). Preceding viral infection was present in 49% of patients. 26% of patients were treated with steroid alone, and 74% of cases were treated with steroid plus acyclovir. Oriental medicine was accompanied in 14% of patients. Among 49 patients who were followed over 4 weeks, 44(90%) had complete recovery. The recovery rates were 68% (4 weeks), 91% (3months), and 100% (10 months). Recurrent rate was 4%. CONCLUSION: The prognosis of Bell palsy in pediatric population was good, and recovery rates were 68% within 4 weeks, and 100% by 10 months after palsy onset.
Subject(s)
Adolescent , Adult , Child , Female , Humans , Male , Academic Medical Centers , Acyclovir , Bell Palsy , Eye Pain , Facial Nerve , Facial Paralysis , Incidence , Medical Records , Medicine, East Asian Traditional , Paralysis , Prognosis , Retrospective Studies , Seasons摘要
PURPOSE: To report a case of bilateral optic disc edema associated with hypocalcemia. CASE SUMMARY: A 48-year-old woman visited our ophthalmology department with decreased vision and disturbance of the visual field in the right eye, which began 2 days prior to presentation. The patient history indicated she had undergone total thyroidectomy 3 months prior and was given an oral calcium preparation. She had no eye pain, headache, tinnitus or diplopia. Her best corrected visual acuity of both eyes was 1.0, and color vision was normal in both eyes although a mild relative afferent pupillary defect was present in the right eye. Severe bilateral optic disc edema was present in the right eye. A Humphrey visual field test revealed an enlarged blind spot and peripheral nasal step scotoma in the right eye. The Cerebrospinal fluid (CSF) opening pressure was within the normal range and there were no abnormal findings regarding CSF. Additionally, there were no remarkable findings on brain magnetic resonance imaging nor neurologic tests. Her serum calcium was 5.9 mg/dL (normal range: total calcium 8.7-10.6 mg/dL), and an intravenous calcium supplement was started. Visual disturbance and optic disc edema improved 2 days after replacement and the optic disc edema completely dissolved 2 months later. CONCLUSIONS: Hypocalcemia may cause bilateral optic disc edema and can be recovered through adequate calcium supplementation, and it is necessary to prevent and promptly detect this rare complication.
Subject(s)
Female , Humans , Middle Aged , Brain , Calcium , Cerebrospinal Fluid , Color Vision , Diplopia , Edema , Eye Pain , Headache , Hypocalcemia , Magnetic Resonance Imaging , Ophthalmology , Optic Disk , Optic Nerve Diseases , Papilledema , Pupil Disorders , Reference Values , Scotoma , Thyroidectomy , Tinnitus , Visual Acuity , Visual Field Tests , Visual Fields摘要
Colored lenses were first designed for patients with eye pathologies, such as aniridia or corneal opacity. However, in recent years they have become readily available over-the-counter as cosmetic accessories. Widespread use of these lenses has been noted among young adults. Acanthamoeba keratitis is a rare cause of corneal infection, which is associated with poor visual prognosis. Over the past ten years, improvements in the management of this infection have been documented, yet the best treatment is still primary prevention. Hence, contact lens wearers must be provided with proper instructions regarding contact lens hygiene. We present a case of unilateral Acanthamoeba keratitis in a cosmetic contact lens wearer who presented with a month history of right eye pain, photophobia, redness and blurred vision. The contact lenses were obtained over the counter, and a history of poor contact lens hygiene was found. The patient was started on empirical treatment initially. The treatment was modified once the diagnosis was confirmed via Giemsa Stain of corneal scrapings, which showed Acanthamoeba cysts. The patient improved markedly and was discharged from the hospital. The disease classically has a slowly progressive, chronic course, with frequent remission periods. Our patient was lost to follow-up due to poor compliance and failure to adhere to guidelines
Subject(s)
Adult , Female , Humans , Cosmetics/adverse effects , Contact Lenses/adverse effects , Hygiene , Eye Pain摘要
PURPOSE: To report a case of delayed infective endophthalmitis associated with exposure of scleral fixation knot. CASE SUMMARY: A 35-year-old female was transferred from a local clinic with sudden onset right eye pain under suspicion of uveitis. The patient received vitrectomy, scleral encircling and lensectomy for rhegmatogenous retinal detachment before 16 years. In addition, she underwent secondary scleral fixation of intraocular lens (IOL) 1 year previously. Best-corrected visual acuity was hand motion and intraocular pressure was 28 mmHg. Slit lamp examination revealed diffuse keratic precipitates and anterior chamber reaction was 4 positive. Exposed scleral fixation knot outside conjunctiva at 2 o' clock combined with suppurative discharge was observed. On fundus examination, red reflex was decreased due to vitreous haze. She was diagnosed as infective endophthalmitis associated with exposure of scleral fixation knot. The patient received vitrectomy and intravitreal injection of antibiotics and vitreous culture. After 2 days, IOL removal, silicone oil tamponade and intravitreal injection of antibiotics were performed due to uncontrolled inflammation with accompanying hypopyon. Hemophilus influenza was isolated in the vitreous sample. Removal of silicone oil was performed at 1 month. There was no recurrent inflammation at 1 year and she received scleral fixation of IOL for the second time. At 1 year and 3 months, corrected visual acuity was 0.4 without signs of inflammation. CONCLUSIONS: In cases of exposed scleral fixation knot after IOL insertion, a risk of endophthalmitis exists. Meticulous care is required when fixation knot is exposed due to thinning of overlying conjunctiva.
Subject(s)
Adult , Female , Humans , Anterior Chamber , Anti-Bacterial Agents , Conjunctiva , Endophthalmitis , Eye Pain , Haemophilus , Hand , Inflammation , Influenza, Human , Intraocular Pressure , Intravitreal Injections , Lenses, Intraocular , Reflex , Retinal Detachment , Silicon , Silicones , Slit Lamp , Uveitis , Visual Acuity , Vitrectomy摘要
RESUMO Objetivo: O objetivo desde estudo foi avaliar a efetividade da triancinolona intra-vítrea e da clorpromazina retrobulbar como alternativas no manejo da dor ocular em olhos cegos. Métodos: Este foi um estudo prospectivo intervencionista não-randomizado de pacientes com olho cego doloroso não responsivo ao tratamento tópico e sem indicação de evisceração atendidos no Serviço de Oftalmologia do Hospital Governador Celso Ramos no ano de 2010. Após exame oftalmológico e ultrassonografia ocular modo B, os pacientes foram divididos em dois grupos. Pacientes do Grupo 1 possuíam glaucoma intratável e receberam injeção retrobulbar de clorpromazina 2,5ml, e pacientes do Grupo 2 possuíam olhos phthisicos com componente inflamatório e receberam injeção intra-vítrea de triancinolona 0,3ml. Foram realizadas avaliações com 1, 3 e 6 meses após o procedimento e a dor quantificada de forma subjetiva em uma escala de 0 a 10 (sem dor e com o máximo de dor, respectivamente). Resultados: Foram incluídos 38 olhos, sendo 15 no Grupo 1 e 21 no Grupo 2. Houve predomínio do sexo masculino e idade média de 54 anos. A causa mais prevalente de olho cego doloroso foi o glaucoma neovascular. Tanto a injeção de clorpromazina retrobulbar quanto a de triancinolona intra-vítrea mostraram-se eficazes no controle da dor ocular em olhos cegos no período do estudo (p<0,001). Ocorreu uma redução de 77,1% no uso de colírios (p<0,01) após a aplicação das medicações. Conclusão: Tanto a injeção de clorpromazina retrobulbar quanto a de triancinolona intra-vítrea mostraram resultados significativos no controle da dor ocular em olhos cegos, além de uma redução no uso de colírios. A clorpromazina é um medicamento de baixo custo, com melhor perfil de efeitos adversos e mostrou resultados discretamente melhores relação à triancinolona. Possíveis viéses identificados no estudo são o de tempo e seleção.
ABSTRACT Objective: The objective of this study was to evaluate the efficacy of intravitreal triamcinolone and retrobulbar chlorpromazine as alternatives in the management of ocular pain in blind eyes. Methods: This was a non-randomized interventional prospective study of patients with painful blind eye unresponsive to topical treatment and without indication of evisceration treated at the Hospital Governador Celso Ramos Ophthalmology Service in 2010. After ocular examination and ocular B mode ultrasound, patients were divided into two groups. Group 1 patients had intractable glaucoma and received retrobulbar injection of chlorpromazine 2.5ml, and Group 2 patients had phthisics eyes with inflammatory component and received intravitreal triamcinolone injection 0.3ml. Evaluations were performed at 1, 3 and 6 months after the procedure and quantified pain subjectively on a scale from 0 to 10 (no pain and maximum pain, respectively). Results: 38 eyes were included, 15 in Group 1 and 21 in Group 2. There was a predominance of males with a mean age of 54 years. The most prevalent cause of painful blind eye was the neovascular glaucoma. Any retrobulbar injection of chlorpromazine as the intravitreal triamcinolone shown to be effective in the control of ocular pain in the eye blind study period (p <0.001). There was a 77.1% reduction in eye drops (p <0.01) after application of medication. Conclusion: Both the retrobulbar injection chlorpromazine as the intravitreal triamcinolone showed significant results in the control of ocular pain in blind eyes, and a reduction in the use of eye drops. Chlorpromazine is a low cost product, with a better adverse effect profile and showed slightly better results compared to triamcinolone. Potential bias identified in the study are the time and selection.
Subject(s)
Humans , Male , Female , Middle Aged , Triamcinolone/administration & dosage , Chlorpromazine/administration & dosage , Blindness/complications , Eye Pain/etiology , Eye Pain/drug therapy , Retinal Vein Occlusion/complications , Retinal Detachment/complications , Triamcinolone/therapeutic use , Chlorpromazine/therapeutic use , Glaucoma, Open-Angle/complications , Glaucoma, Neovascular/complications , Prospective Studies , Diabetic Retinopathy/complications , Intravitreal Injections , Injections , Intraocular Pressure摘要
BACKGROUND AND OBJECTIVES: management of pain in painful blind eyes is still a challenge. Corticosteroids and hypotensive agents, as well as evisceration and enucleation, are some of the strategies employed so far that are not always effective and, depending on the strategy, cause a deep emotional shock to the patient. Given these issues, the aim of this case report is to demonstrate a new and viable option for the management of such pain by treating the painful blind eye with the stellate ganglion block technique, a procedure that has never been described in the literature for this purpose. CASE REPORT: six patients with painful blind eye, all caused by glaucoma, were treated; in these patients, VAS (visual analogue scale for pain assessment, in which 0 is the absence of pain and 10 is the worst pain ever experienced) ranged from 7 to 10. We opted for weekly sessions of stellate ganglion block with 4 mL of bupivacaine (0.5%) without vasoconstrictor and clonidine 1 mcg/kg. Four patients had excellent results at VAS, ranging between 0 and 3, and two remained asymptomatic (VAS = 0), without the need for additional medication. The other two used gabapentin 300 mg every 12 h. CONCLUSION: currently, there are several therapeutic options for the treatment of painful blind eye, among which stand out the retrobulbar blocks with chlorpromazine, alcohol and phenol. However, an effective strategy with low rate of serious complications, which is non-mutilating and improves the quality of life of the patient, is essential. Then, stellate ganglion block arises as a demonstrably viable and promising option to meet this demand.
JUSTIFICATIVA E OBJETIVOS: o manejo da dor em olhos cegos dolorosos ainda é um desafio. Corticosteroides e hipotensores, bem como evisceração e enucleação, são algumas das estratégias até então empregadas, nem sempre eficazes e que, a depender da estratégia, causam um profundo abalo emocional no paciente. Dadas essas questões, o objetivo deste relato de caso é demonstrar uma nova e viável opção para o manejo desse tipo de dor por meio do tratamento do olho cego doloroso com bloqueios de gânglio cervicotorácico, técnica nunca descrita na literatura para esse fim. RELATO DE CASO: foram tratados seis pacientes portadores de olho cego doloroso, todos por glaucoma, nos quais a EVA (escala visual analógica para avaliação da dor em que 0 é ausência de dor e 10 é a maior dor já experimentada) variava de 7 a 10. Optou-se por sessões semanais de bloqueio de gânglio cervicotorácico com 4 mL de bupivacaína (0,5%) sem vasoconstritor e clonidina 1 mcg/Kg. Quatro pacientes apresentaram excelente resultado EVA, com variação entre 0 e 3, e dois permaneceram assintomáticos (EVA = 0), sem necessidade de medicação suplementar. Os outros dois usaram gabapentina 300 mg de 12 em 12 horas. CONCLUSÃO: atualmente, várias são as opções terapêuticas para o tratamento do olho cego doloroso, entre as quais se destacam os bloqueios retrobulbares com clorpromazina, álcool e fenol. No entanto, uma estratégia eficaz, com pequeno índice de complicações graves, não mutilante e que melhore a qualidade de vida do paciente é imprescindível. O bloqueio do gânglio cervicotorácico surge, pois, como uma opção comprovadamente viável e promissora para atender a essa demanda.
Subject(s)
Humans , Female , Autonomic Nerve Block/methods , Glaucoma/complications , Eye Pain/drug therapy , Anesthetics, Local/administration & dosage , Quality of Life , Stellate Ganglion , Pain Measurement , Bupivacaine/administration & dosage , Blindness/etiology , Treatment Outcome , Cyclohexanecarboxylic Acids/therapeutic use , Eye Pain/etiology , Gabapentin , gamma-Aminobutyric Acid/therapeutic use , Amines/therapeutic use , Analgesics/therapeutic use摘要
RESUMO Objetivo: Comparar a efetividade da dipirona versus o ibuprofeno para a redução da dor na fotocoagulação da retina (FR). Método: Foi realizado um estudo controlado, duplo cego e randomizado englobando trinta e quatro pacientes com retinopatia diabética separados em dois grupos. Grupo A recebeu 1000mg de dipirona e o grupo B recebeu 600mg de ibuprofeno. A dor foi avaliada pela escala visual analógica. Resultado: A média do escore da dor nos grupos A e B foi de 5,2 ± 2.6 e 4,5 ± 1,4, respectivamente. Não houve diferença estatística entre os grupos (p=0,34). O mesmo foi observado quanto à analise entre dor leve, moderada e grave (p=0,09). Os grupos foram semelhantes quanto à idade e sexo. Conclusão: Os medicamentos foram equivalentes ou equipotentes em reduzir a dor ocular durante a fotocoagulação a laser da retina.
ABSTRACT Objective: To compare the effectiveness of metamizole versus ibuprofen for the reduction of pain in retinal photocoagulation (RP). Method: A double-masked randomized controlled study was performed. Thirty-four patients with diabetic retinopathy were enrolled. The patients were randomized into two groups. Group A received oral 1000 mg metamizole. Group B received an oral intake of 600 mg ibuprofen. Pain during RP was assessed using a visual analog scale. Results: The mean pain scores for groups A and B were 5.2±2.6 and 4.5±1.4 (p=0.34). There were no significant differences in the mean pain scores between the two groups. The same is observed when analyzing by low, medium and high pain (p=0.09). The groups were similar in age and gender. Conclusion: Both drugs were equivalents or equipotent in reduce ocular pain during retinal photocoagulation.