摘要
O osteoblastoma é um tumor frequentemente visto em ossos longos, com pouco envolvimento maxilofacial e raramente localizado em osso zigomático. Devido à sua semelhança clínica e histológica com outros tumores ósseos, o osteoblastoma representa um desafio de diagnóstico para o profissional. A ressecção cirúrgica total é recomendada, sendo que a ausência de recidiva se deve ao diagnóstico correto e tratamento adequado. O objetivo deste artigo é relatar o manejo de um paciente com osteoblastoma envolvendo o osso zigomático e realizar uma breve revisão da literatura.
Osteoblastoma is a tumor often seen in long bones, with little maxillofacial involvement and rarely located in zygomatic bone. Due to its clinical and histological similarity with other bone tumors, osteoblastoma represents a diagnostic challenge for the professional. Total surgical resection is recommended, and the absence of recurrence is due to correct diagnosis and adequate treatment. The aim of this article is to report the management of a patient with osteoblastoma involving the zygomatic bone and to carry out a brief review of the literature.
Subject(s)
Humans , Male , Aged , Zygoma , Bone Neoplasms , Osteoblastoma/diagnosis摘要
El osteosarcoma "tipo osteoblastoma", una variante menos agresiva del osteosarcoma, es una enfermedad poco frecuente y representa un desafío diagnóstico tanto clínico como histopatológico. Se han publicado escasos reportes de casos de este tumor. Presentamos a un paciente de 16 años con un osteosarcoma "tipo osteoblastoma" localizado en la columna cervical. La biopsia ósea bajo tomografía reveló una lesión con un patrón de crecimiento permeativo, con sospecha de osteosarcoma "tipo osteoblastoma". Se realizó una espondilectomía total en bloque mediante un doble abordaje. Se describen el caso clínico, la secuencia diagnóstica, la técnica quirúrgica y el seguimiento a 10 años. Nivel de Evidencia: IV
Osteoblastoma-like osteosarcoma, a less aggressive variant of osteosarcoma, is a rare tumor which presents a clinical and histopathological diagnostic challenge. We have found few reports of cases of this tumor in the literature. In this case, we describe an osteoblastoma-like osteosarcoma of the cervical spine in a 16-year-old patient. CT-guided bone biopsy showed a lesion with a permeated growth pattern, which led to the suspicion of an osteoblastoma-like osteosarcoma. A total en bloc spondylectomy was performed through a dual approach. We present the clinical case, the diagnostic sequence, the surgical technique and 10-year follow-up results. Level of Evidence: IV
Subject(s)
Adolescent , Bone Neoplasms/surgery , Osteosarcoma/surgery , Osteosarcoma/diagnosis , Cervical Vertebrae/pathology , Osteoblastoma/surgery , Osteoblastoma/diagnosis摘要
El Osteoblastoma (OB) es un tumor benigno formador de tejido óseo de aparición muy rara en los maxilares. Su diagnóstico puede ser un gran reto para el patólogo bucal, ya que las características histopatológicas se asemejan a otros tumores más frecuentes en el macizo maxilofacial; por lo que es importante conocer a profundidad sus características clínicas, radiográficas e histopatológicas que nos conduzcan al diagnóstico asertivo de OB. Hasta los actuales momentos la última recopilación de casos de OB maxilares publicados en la literatura fue hecha por Morelos et al hasta el año 2011, quien obtuvo 88 casos. El objetivo de esta investigación fue realizar una revisión bibliográfica exhaustiva de casos documentados hasta la fecha en revisiones sistemáticas previas, obteniéndose 119 casos de OB maxilares. Adicionalmente, se aporta un caso más de OB de maxilar superior a la literatura académica...
Osteoblastoma is a rare bone-forming tumor that very rarely involves the jaws. The diagnosis should be very difficult to oral pathology expert because their histopathologic features are resembled with other bony tumors of the maxillofacial region. Therefore, is very important have depth knowledge about the clinical, radiographic and histopathologic features of OB, to make the correct diagnosis. Before this report, the last collection of maxillary OB cases was made by Morelos et al until the year 2011; they obtained 88 cases in their study. The main aim of this research was provide a systematic review of previously published cases; the result was 119 cases of maxillary OB. In addition, this paper added one more case of this rare lesion to the academic literature...
Subject(s)
Humans , Male , Adolescent , Adult , Female , Child , Young Adult , Fibroma, Ossifying/diagnosis , Fibroma, Ossifying/physiopathology , Bone and Bones/anatomy & histology , Bone and Bones/pathology , Maxillary Sinus Neoplasms/physiopathology , Osteoblastoma/diagnosis , Osteoblastoma/pathology , Bone Neoplasms , Mouth Neoplasms , Osteogenesis , Pathology, Oral摘要
Osteoid osteoma is a benign tumor of the bone which arises from osteoblasts and is extremely rare in jaws. Only 15 cases of osteoid osteoma have been reported in English-language literature. This case report is presented here due to its rarity.
Subject(s)
Adolescent , Diagnosis, Differential , Female , Fibroma, Ossifying/diagnosis , Humans , Mandibular Diseases/diagnosis , Mandibular Neoplasms/diagnosis , Osteitis/diagnosis , Osteoblastoma/diagnosis , Osteoma, Osteoid/diagnosis摘要
O osteoblastoma é uma neoplasia óssea que na maioria das circunstâncias apresenta-se com aspecto radiológico de baixa agressividade, porém em alguns casos pode adquirir caráter agressivo com rompimento da cortical óssea e invasão de estruturas adjacentes. A maioria das lesões ocorrena coluna vertebral, particularmente nos arcos posteriores, podendo eventualmente estender-se para o corpo vertebral. O diagnóstico diferencial das formas agressivas se faz principalmente com os osteossarcomas. O artigo constitui-se no relato de dois casos com padrões radiológicos agressivos e confirmação histológica de osteoblastomas da coluna vertebral.
Osteoblastoma is a bone neoplasy that in most circumstances present a low aggressive aspect on radiographic studies, but in some cases may acquire an aggressive pattern, rupturing the bone cortex and invading nearby structures. Most cases occur on thevertebral column, especially at the posterior arch and occasionallyinvolving the vertebral body. Differential diagnosis of the aggressive form is made with osteosarcomas. This review reports two cases of osteoblastomas involving vertebral column, with an aggressive pattern on radiologic studies, and their histologic confirmation.
Subject(s)
Humans , Male , Adolescent , Young Adult , Spine/pathology , Osteoblastoma/diagnosis , Tomography, X-Ray Computed , Cervical Vertebrae , Diagnosis, Differential , Osteosarcoma摘要
This study comprises of 12 cases of osteoblastoma. There were 8 males and 4 females, with a mean age of 17.8 years. The vertebral column, including the sacrum was the most frequent site (10 of 12 cases). Radiologically the lesions were lytic, well circumscribed and expansile. The histology consisted of intercommunicating osteoid seams lined by plump osteoblasts with numerous intervening ectatic stromal vessels. Despite these characteristic features, the distinction of osteoblastoma from osteoblastic osteosarcoma can at times be very problematic. The lack of lace-like osteoid or sheets of osteoblasts, and inconspicuous mitotic activity are useful distinguishing features. The purpose of this communication is to highlight the microscopic features for the correct recognition of osteoblastoma and its distinction from other osteoid forming bone lesions.
Subject(s)
Adolescent , Adult , Bone Neoplasms/diagnosis , Child , Diagnosis, Differential , Female , Humans , Male , Osteoblastoma/diagnosis , Osteosarcoma/diagnosis , Spine/pathology摘要
O fibroma ossificante juvenil (FOJ) é uma neoplasia benigna que tem sido distinguida dos fibromas ossificantes pela idade dos pacientes afetados (geralmente abaixo dos 15 anos), sítio anatômico preferencial de ocorrência (maxila), e comportamento biológico agressivo. Nós relatamos um caso atípico de um FOJ de grandes dimensões envolvendo a maxila direita de uma paciente de 28 anos que provocou perfuração das corticais ósseas vestibular e palatina em seis meses deevolução. Uma ampla discussão de critérios histológicos para estabelecimento do diagnóstico deste tumor também foi realizada
Subject(s)
Humans , Female , Adult , Fibroma, Ossifying/surgery , Fibroma, Ossifying/diagnosis , Fibroma, Ossifying/pathology , Fibroma, Ossifying , Bone Neoplasms/diagnosis , Bone Neoplasms/pathology , Diagnosis, Differential , Osteoblastoma/diagnosis , Osteoblastoma/pathology摘要
A case of benign osteoblastoma affecting posterior element of spine with pain and paraplegia in a female is being presented with brief review of literature. Early diagnosis and surgical excision remains the mainstay of treatment.
Subject(s)
Adolescent , Female , Humans , Magnetic Resonance Imaging , Osteoblastoma/diagnosis , Spinal Neoplasms/diagnosis摘要
Benign osteoblastoma is an uncommon bone tumor accounting for approximately 1 percent of all bone tumors. There are only 35 cases of skull osteoblastoma reported in the literature. We describe the case of a 23 year old male with a giant osteoblastoma of temporal bone submitted to a total removal of the tumor after an effective embolization of all external carotid branches. The authors discuss diagnostic and management aspects of this uncommon skull tumor.
Subject(s)
Humans , Male , Adult , Bone Neoplasms , Osteoblastoma , Temporal Bone , Bone Neoplasms/diagnosis , Bone Neoplasms/surgery , Osteoblastoma/diagnosis , Osteoblastoma/surgery , Temporal Bone/surgery摘要
El osteoblastoma es una neoplasia benigna, rara, de origen osteoblástico. Se caracteriza por ser una lesión de crecimiento lento y asintomático que en ocasiones puede sufrir transformación sarcomatosa. Se localiza en huesos craneomandibulares en el 14.6 por ciento de los casos. El objetivo de este trabajo fue determinar la frecuencia de osteoblastoma en maxilar y mandíbula, su distribución de acuerdo a la edad y sexo de los pacientes, así como su sintomatología. Se realizó una revisión de la literatura y se encontraron 44 casos registrados. De ellos, 32 se localizaron en la mandíbula (73 por ciento) y 12 en maxilares (27 por ciento). Predominaron en los varones con una relación hombre mujer de 1.5:1. Las edades variaron entre los cinco y 38 años, teniendo mayor incidencia entre los 10 y 19 años de edad. En general, las lesiones medían desde 0.7 hasta 7.5 cm. El 90.3 por ciento de los casos presentaron dolor y todos mostraron aumento de volumen. Debido a su comportamiento biológico, es necesario hacer una minuciosa observación microscópica que, aunada a los datos clínicos y radiográficos, permita establecer el diagnóstico de osteoblastoma
Subject(s)
Humans , Male , Female , Child, Preschool , Adolescent , Adult , Jaw/pathology , Maxillary Diseases/diagnosis , Maxillary Diseases/pathology , Osteoblastoma/diagnosis , Osteoblastoma/physiopathology摘要
A case of osteoblastoma of the spine in a sixty year old female is presented. These lesions usually get misdiagnosed as tuberculosis or malignancy of the spine. Salient diagnostic features have been discussed.
Subject(s)
Diagnosis, Differential , Female , Humans , Middle Aged , Osteoblastoma/diagnosis , Spinal Neoplasms/diagnosis , Tomography, X-Ray Computed , Tuberculosis, Spinal/diagnosis摘要
Os autores estudam 24 pacientes com diagnostico anatomopatologico de osteoblastoma, sendo 22 benignos e dois malignos, tratados no periodo compreendido de 1953 a 1996, com seguimento medio de 33,4 meses. Foram operados 22 pacientes, sendo em dois utilizada a embolizacao seletiva, pela impossibilidade de tratamento cirurgico devido a localizacao pelvica em um caso e coluna toracica em outro. Discutem os aspectos clinicos e radiograficos observados. Analisam os resultados segundo os criterios clinicos de dor, aumento de volume e complicacoes apresentadas. Obtiveram 20 bons resultados, com uma complicacao por infeccao. Concluem que a abordagem terapeutica do osteoblastoma depende do diagnostico histologico preciso, do volume e da regiao acometida
Subject(s)
Humans , Male , Female , Child, Preschool , Child , Adolescent , Adult , Bone Neoplasms/surgery , Osteoblastoma/diagnosis , Osteoma, Osteoid/diagnosis , Diagnosis, Differential摘要
A técnica da prata coloidal para a identificaçäo das regiöes organizadoras nucleolares (AgNOR) foi aplicada em 20 espécimes parafinizados de lesöes ósseas dos maxilares, sendo 05 osteossarcomas, 05 osteoblastomas, 05 osteomas e 05 fibromas ossificantes centrais, obtidos do arquivo de patologia cirúrgica da Disciplina de Patologia Bucal da Faculdade de Odontologa da Universidade de Säo Paulo. Os resultados mostraram que, além de aplicável em tecido ósseo descalcificado, a técnica do AgNOR demostrou o maior número de NORs dos osteossarcomas em relaçäo às demais neoplasias estudadas, podendo ser útil para o diagnóstico diferencial dessa entidade