Emergence of Trichosporon mycotoxinivorans (Apiotrichum mycotoxinivorans) invasive infections in Latin America
Mem. Inst. Oswaldo Cruz
; 112(10): 719-722, Oct. 2017. graf
Article
ي En
| LILACS
| ID: biblio-1040562
المكتبة المسؤولة:
BR1.1
ABSTRACT
We report the first two cases of Trichosporon mycotoxinivorans infections in Latin America. We also conducted a literature review and a microbiological investigation, including that of clinical and environmental isolates. A 30-year-old man with chronic renal failure had disseminated infection after dialysis and a 15-year-old boy with cystic fibrosis (CF) had pulmonary exacerbations with positive respiratory samples. A review of the relevant literature revealed that deep-seated infections were related to immunosuppression or invasive devices, while most of the CF patients showed a decline in lung function after positive cultures. Phylogenetic analyses revealed three distinct circulating genotypes. MALDI-TOF mass spectrometry analysis showed similar spectral profiles and correctly identified all strains/isolates. Biofilm production was documented in a bloodstream isolate and biofilm-producing cells showed high minimum inhibitory concentrations against antifungals.
Key words
النص الكامل:
1
الفهرس:
LILACS
الموضوع الرئيسي:
Trichosporon
/
Trichosporonosis
نوع الدراسة:
Prognostic_studies
المحددات:
Adolescent
/
Adult
/
Humans
/
Male
البلد/الأقليم حسب الموضوع:
America do sul
/
Brasil
اللغة:
En
مجلة:
Mem. Inst. Oswaldo Cruz
موضوع المجلة:
MEDICINA TROPICAL
/
PARASITOLOGIA
السنة:
2017
نوع:
Article