Preliminary assessment of anti-α-Gal IgG and IgM levels in patients with patent Plasmodium vivax infection
Mem. Inst. Oswaldo Cruz
; 114: e190145, 2019. tab, graf
Article
ي En
| LILACS
| ID: biblio-1040609
المكتبة المسؤولة:
BR1.1
ABSTRACT
Anti-α-Gal responses may exert a protective effect in falciparum malaria. However, the biological role of such antibodies is still unknown during Plasmodium vivax infections. We investigated IgG and IgM responses to α-Gal in individuals with vivax malaria. Anti-α-Gal IgG and IgM levels were higher in these patients than in controls, but no significant correlation was found between parasitaemia and anti-α-Gal response, nor between this response and ABO blood group status. This is the first study to investigate anti-α-Gal antibodies in P. vivax-infected patients; a larger survey is necessary to achieve a better understanding of host immune response during vivax malaria.
Key words
النص الكامل:
1
الفهرس:
LILACS
الموضوع الرئيسي:
Plasmodium vivax
/
Immunoglobulin G
/
Immunoglobulin M
/
Antibodies, Anti-Idiotypic
/
Malaria, Vivax
المحددات:
Adult
/
Humans
اللغة:
En
مجلة:
Mem. Inst. Oswaldo Cruz
موضوع المجلة:
MEDICINA TROPICAL
/
PARASITOLOGIA
السنة:
2019
نوع:
Article