Skin disorders in renal transplant recipients: a retrospective study
An. bras. dermatol
; 92(5): 638-641, Sept.-Oct. 2017. tab
Article
ي En
| LILACS
| ID: biblio-887038
المكتبة المسؤولة:
BR1.1
ABSTRACT
Abstract Background:
Immunosuppressive therapy, which is necessary to avoid graft rejection in renal transplant recipients, presents an increased risk of several pathologies, namely infectious and neoplastic.Objectives:
To identify the most frequent skin diseases and their clinical and demographical risk factors within a population of renal transplant recipients.Methods:
A retrospective study of renal transplant recipients referred to dermatology visit and observed for the first time from January 2008 to December 2014.Results:
The study included 197 patients, 120 men (60,9%). Mean age was 50,7 years (±13,4). 12 patients (6,1%) had previous skin cancer. Infections were the most frequent reason of referral (93/197; 44%). From the total referred, 18,3% (36/197) presented pre-cancerous lesions. Malignancy was diagnosed in 36 patients (18,3%), with 29 non-melanoma skin cancers (14,7%) and 7 Kaposi sarcomas (3,6%). Ratio of basal cell carcinoma to squamous cell carcinoma was 1,11. Non-melanoma skin cancer was significantly associated with older age (p = 0,002), male gender (p = 0,028), history of previous skin cancer (p = 0,002) and higher duration of immunosuppressive therapy (p<0,001). Studylimitations:
Retrospective study, with data from the first visit in dermatology. We didn't made classification on skin-types.Conclusions:
The great incidence of cutaneous infections and skin cancer is responsible for a significant morbidity. It is important to assure the regular dermatological follow-up of renal transplant recipients, which will promote the prevention, an early diagnosis and an efficient treatment.Key words
النص الكامل:
1
الفهرس:
LILACS
الموضوع الرئيسي:
Skin Diseases
/
Immunosuppression Therapy
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Kidney Transplantation
نوع الدراسة:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
المحددات:
Adult
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Aged
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Female
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Humans
/
Male
اللغة:
En
مجلة:
An. bras. dermatol
موضوع المجلة:
DERMATOLOGIA
السنة:
2017
نوع:
Article