Gestational trophoblastic disease with metastasis to kidney. Case report

ABSTRACT

Choriocarcinoma is the most malignant tumor of the gestational trophoblastic neoplasm. It grows rapidly and metastasizes to the lung liver, brain, and less frequently to the other organs. Renal involvement is rare however we encountered a female patient with metastatic choriocarcinoma of the both kidneys. In this article a young woman with multiple metastases from choriocarcinoma is presented. She suffered from prolonged vaginal bleeding, permanent headache, and fever only five months after her first vaginal delivery. Investigation revealed uterus choriocarcinoma with multiple metastases to lung and liver, brain, and both kidneys. Our patient was treated with chemotherapy, radiotherapy and at the end of these treatment all metastases were cured. After a period of sixty months of treatment in serial follow-up, she is well with no sign of recurrent disease