JABHS-Journal of the Arab Board of Health Specializations. 2010; 11 (1): 70-74
ي En
| IMEMR
| ID: emr-98163
المكتبة المسؤولة:
EMRO
ABSTRACT
Glucagonoma is a rare islet cell tumor [alpha cell tumor] of the pancreas, when active it produces a syndrome characterized by necrolytic migratory erythema, diabetes mellitus, weight loss, anemia, glossitis, thromboembolism, neuropsychatric disturbances and hyperglucagonaemia. We present a case of a large pancreatic head tumor with diabetes mellitus [DM], anemia, weight loss and muscle wasting. After complete resection of the pancreatic tumor, the hyperglycaemia subsided. Peviewing 120 cases of glucagonoma in the literature the average tumor diameter was 3.6 cm. Most of the tumors [90%] occurred in the body and the tail. Two thirds of the reported glucagonomas were malignant and 53.3% metastasizes to other organs. Necrolytic migratory erythema [NME] is not a prerequisite for the diagnosis of Glucagonoma syndrome, where anemia, hyperglycemia, muscle wasting and weight loss may be the presenting features
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الفهرس:
IMEMR
الموضوع الرئيسي:
Prognosis
/
Treatment Outcome
/
Streptozocin
/
Glucagonoma
/
Neoplasm Metastasis
نوع الدراسة:
Case_reports
المحددات:
Humans
/
Male
اللغة:
En
مجلة:
J. Arab Board Health Special.
السنة:
2010