Protein thermostability in Archaea and Eubacteria
Genet. mol. res. (Online)
; Genet. mol. res. (Online);5(4): 816-827, 2006.
Article
ي En
| LILACS
| ID: lil-482077
المكتبة المسؤولة:
BR1.1
ABSTRACT
In order to survive at high temperatures, thermophilic prokaryotes (Archaea and Eubacteria) adopt different strategies. Among several important contributing factors for stability of proteins are CG-rich codons, the ratio of charged amino acids compared to uncharged amino acids, ionic interactions, amino acid preferences and their distribution, post-translational modifications, and solute accumulation. However, these factors may differ from taxon to taxon, both within and between species depending upon the composition of proteins found in these organisms. This is exemplified in the case of differences in strategies adopted by soluble proteins and membrane proteins. Therefore, it appears that no single factor or combination of factors together can be universally attributed to the provision of thermal stability in proteins.
Key words
النص الكامل:
1
الفهرس:
LILACS
الموضوع الرئيسي:
Thermodynamics
/
Bacteria
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Bacterial Proteins
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Archaea
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Archaeal Proteins
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Hot Temperature
اللغة:
En
مجلة:
GMR
/
Genet Mol Res
/
Genet. mol. res. (Online)
/
Genetics and molecular research
موضوع المجلة:
BIOLOGIA MOLECULAR
/
GENETICA
السنة:
2006
نوع:
Article