Risk factors of oropharyngeal carriage of Pseudomonas aeruginosa among patients from a Medical-Surgical Intensive Care Unit
Braz. j. infect. dis
; 13(3): 173-176, June 2009. tab
Article
ي En
| LILACS
| ID: lil-538516
المكتبة المسؤولة:
BR1.1
ABSTRACT
Oropharyngeal carriage of Pseudomonas aeruginosa is associated with increased risk of infection and may provide a source for spread of drug-resistant strains. In order to assess the incidence and risk factors of oropharyngeal carriage, we conducted a retrospective cohort study based on results of surveillance cultures (oropharyngeal swabs) from a medical-surgical intensive care unit, collected from March 2005 through May 2006. Variables investigated included demographic characteristics, comorbid conditions, invasive procedures, use of devices and use of antimicrobials. Thirty case patients with P. aeruginosa carriage were identified. Other 84 patients with surveillance cultures negative to P. aeruginosa were enrolled as control subjects. Case patients were more likely to have a solid malignancy (Odds Ratio [OR] = 12.04, 95 percent Confidence Interval [CI] = 1.93-75.09, p=0.008), Acquired Immunodeficiency Syndrome (AIDS, OR = 7.09, 95 percent CI= 1.11-45.39, p = 0.04), central nervous system disease (OR = 4.51, 95 percent CI = 1.52-13.39, p = 0.007), or to have a central venous catheter placed (OR = 7.76, 95 percent CI = 1.68-35.79, p=0.009). The use of quinolones was a protective factor (OR = 0.13, 95 percent CI = 0.03-0.47, p = 0.002). The predominance of comorbidities as risk factors points out a group of patients to whom preventive measures should be directed.
Key words
النص الكامل:
1
الفهرس:
LILACS
الموضوع الرئيسي:
Oropharynx
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Pseudomonas aeruginosa
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Pseudomonas Infections
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Carrier State
نوع الدراسة:
Etiology_studies
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Incidence_studies
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Observational_studies
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Prognostic_studies
/
Risk_factors_studies
المحددات:
Female
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Humans
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Male
اللغة:
En
مجلة:
Braz. j. infect. dis
موضوع المجلة:
DOENCAS TRANSMISSIVEIS
السنة:
2009
نوع:
Article