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Evaluation of the social, clinical and laboratorial profile of patients diagnosed with leprosy in a reference center in São Paulo
Porto, Ana Carolina Souza; Figueira, Renata Borges Fortes Costa; Barreto, Jaison Antônio; Lauris, José Roberto Pereira.
Affiliation
  • Porto, Ana Carolina Souza; Universidade Federal de São Paulo. São Paulo. BR
  • Figueira, Renata Borges Fortes Costa; Universidade Federal de São Paulo. São Paulo. BR
  • Barreto, Jaison Antônio; Universidade Federal de São Paulo. São Paulo. BR
  • Lauris, José Roberto Pereira; Universidade Federal de São Paulo. São Paulo. BR
An. bras. dermatol ; 90(2): 169-177, Mar-Apr/2015. tab, graf
Article ي En | LILACS | ID: lil-741078
المكتبة المسؤولة: BR1.1
ABSTRACT

BACKGROUND:

Leprosy is the main infectious cause of disability. It is said to be eradicated in São Paulo since 2005, but diagnosis is still late.

OBJECTIVES:

To investigate the social, clinical and laboratorial profile of leprosy patients diagnosed between 01/2007 and 12/2011, in a reference center in São Paulo.

METHODS:

Retrospective descriptive study. Data of all new leprosy cases diagnosed between 01/2007 and 12/2011 were raised in São Paulo.

RESULTS:

103 men and 71 women were diagnosed, most of them were multibacillary. Mean age at diagnosis was 49 yrs; 2,2% were children; 70% had incomplete primary education; 50% were referred without diagnostic suspicion of leprosy. Mean time since first symptoms/signs and diagnosis was 2 years; 64% of patients had some degree of disability, and 26% had grade 2. 23 cases were diagnosed only after being summoned, and 80% of these had no disability. Agreement between the Ridley and Jopling and the WHO classification was 75% (kappa index = 0.44). Serology for IgM anti-PGL1 (87 patients) showed a mean value of 0.25, and an association between MB classification and test positivity (p <0.001).

CONCLUSIONS:

Leprosy diagnosis in São Paulo is late. The disease mainly affected the socially disadvantaged and economically active population. Failure to detect the disease (41% in the last 10 years) could be due to the lack of suspicion and to decentralization. For the classification of patients with advanced leprosy, both the WHO and R&J classifications proved to be helpful tools. .
الموضوعات
Key words

النص الكامل: 1 الفهرس: LILACS الموضوع الرئيسي: Leprosy نوع الدراسة: Diagnostic_studies / Observational_studies / Risk_factors_studies المحددات: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male البلد/الأقليم حسب الموضوع: America do sul / Brasil اللغة: En مجلة: An. bras. dermatol موضوع المجلة: DERMATOLOGIA السنة: 2015 نوع: Article

النص الكامل: 1 الفهرس: LILACS الموضوع الرئيسي: Leprosy نوع الدراسة: Diagnostic_studies / Observational_studies / Risk_factors_studies المحددات: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male البلد/الأقليم حسب الموضوع: America do sul / Brasil اللغة: En مجلة: An. bras. dermatol موضوع المجلة: DERMATOLOGIA السنة: 2015 نوع: Article