Serodiagnosis of extra pulmonary tuberculosis using A-60 antigen.
Article
ي En
| IMSEAR
| ID: sea-112446
ABSTRACT
The diagnosis of extrapulmonary tuberculosis including neurotuberculosis is difficult because of the low yield of culture positivity for Mycobacterium tuberculosis (M. tb). Serodiagnosis has emerged as a useful aid to the diagnosis of extrapulmonary tuberculosis. The utility and efficacy of detection of antimycobacterial antibodies to A-60 antigen in serum and/or cerebrospinal fluid (CSF) was analysed in 100 patients-neurotuberculosis-72, abdominal tuberculosis-12 and others-16. The overall positivity rate for the test was 75%. The positivity rate of the test in serum and/or CSF was 79.2% (57 of 72) in neurotuberculosis and 62.5% (10 of 16) for other forms of extrapulmonary tuberculosis. The positivity rate for antimycobacterial antibodies was higher for patients with tubercular meningitis -94.7%. To conclude, testing for antimycobacterial antibodies to A-60 antigen is a useful adjunct in the diagnosis of extrapulmonary tuberculosis especially neurotuberculosis.
النص الكامل:
1
الفهرس:
IMSEAR
الموضوع الرئيسي:
Tuberculin
/
Tuberculosis
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Tuberculosis, Meningeal
/
Humans
/
Serologic Tests
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Sensitivity and Specificity
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Antibodies, Bacterial
/
Mycobacterium tuberculosis
/
Antigens, Bacterial
نوع الدراسة:
Diagnostic_studies
اللغة:
En
السنة:
2001
نوع:
Article