Does autopsy of antenatally diagnosed malformed foetuses aid genetic counselling?
Article
ي En
| IMSEAR
| ID: sea-118418
ABSTRACT
BACKGROUND:
Many pregnancies are terminated because of ultrasonographic diagnosis of malformation in the foetus. A detailed foetal autopsy is needed to arrive at a definite diagnosis on the basis of which genetic counselling can be provided.METHODS:
Sixty-one foetuses, terminated because of antenatal diagnosis of congenital malformations by ultrasound, were autopsied. The ultrasound diagnosis was compared with the diagnosis reached after autopsy.RESULTS:
In 31 cases (51%) the autopsy provided additional findings. In 21 cases (34.4%), the autopsy changed the primary diagnosis. The revised diagnosis led to a change in the risk of recurrence in 18 cases (29.5%).CONCLUSION:
Genetic counselling depending solely on ultrasonographic foetal diagnosis may be erroneous. For appropriate genetic counselling, a detailed foetal examination should be carried out after termination in cases with ultrasonographically detected congenital malformations.
النص الكامل:
1
الفهرس:
IMSEAR
الموضوع الرئيسي:
Autopsy
/
Congenital Abnormalities
/
Female
/
Humans
/
Pregnancy
/
Ultrasonography, Prenatal
/
Genetic Counseling
نوع الدراسة:
Diagnostic_studies
اللغة:
En
السنة:
1998
نوع:
Article