Free radical toxicity and antioxidants in Parkinson's disease.
Neurol India
; 2003 Mar; 51(1): 60-2
Article
ي En
| IMSEAR
| ID: sea-121690
ABSTRACT
Erythrocyte lipid peroxidation, oxidative hemolysis, erythrocyte antioxidant enzymes, viz. superoxide dismutase, glutathione reductase, glutathione peroxidase, catalase and plasma antioxidants, viz. vitamin A, vitamin E, vitamin C and ceruloplasmin have been determined by spectrophotometric methods in 15 patients with Parkinson's disease (PD) and in 50 controls. Lipid peroxidation, oxidative hemolysis and plasma ceruloplasmin were significantly higher in PD patients as compared to normals. Erythrocyte antioxidants in PD patients were not significantly different from the controls. However, plasma vitamin C in PD patients was significantly lower than the controls. It is concluded that these patients are under oxidative stress which points to a possible involvement of free radicals in PD.
النص الكامل:
1
الفهرس:
IMSEAR
الموضوع الرئيسي:
Parkinson Disease
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Female
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Humans
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Male
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Lipid Peroxidation
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Oxidative Stress
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Adult
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Erythrocytes
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Free Radicals
/
Middle Aged
اللغة:
En
مجلة:
Neurol India
السنة:
2003
نوع:
Article