Adolescent; Adult; Alkaline Phosphatase/metabolism; Animals; Bone and Bones/pathology; Child; Female; Humans; Hypophosphatemia/complications; Hypophosphatemia/diagnosis; Hypophosphatemia/therapy; Male; Middle Aged; Osteomalacia/complications; Osteomalacia/diagnosis; Osteomalacia/therapy; Phosphates/blood; Phosphates/chemistry; Rickets/complications; Rickets/diagnosis; Rickets/therapy; Treatment Outcome; Vitamin D/analogs & derivatives; Vitamin D/metabolism