Lichenoid pseudovesicular papular eruption on nose: A papular facial dermatosis probably related to actinic lichen nitidus or micropapular polymorphous light eruption
Indian J Dermatol Venereol Leprol
; 2019 Nov; 85(6): 597-604
Article
| IMSEAR
| ID: sea-192531
ABSTRACT
Background:
Facial papules are a feature of several clinical conditions and may present both diagnostic and therapeutic challenges.Aim:
To describe a grouped papular eruption on the nose and adjoining cheeks that has not been well characterized previously. Materials andMethods:
A series of consecutive patients with a papular eruption predominantly involving nose and cheeks were evaluated, treated and followed up prospectively at tertiary care centers. Demographic details, clinical features, histopathology and response to treatment were recorded.Results:
There were five men and six women (mean age 29.9 ± 6.9 years) who had disease for a mean duration of 17.3 ± 11.1 months. All patients presented with a predominantly asymptomatic eruption of monomorphic, pseudovesicular, grouped, skin colored to slightly erythematous papules prominently involving the tip of nose, nasal alae, philtrum and the adjoining cheeks. A total of 15 biopsies from 11 patients were analyzed and the predominant finding was a dense, focal lymphoid infiltrate restricted to the upper dermis with basal cell damage and atrophy of the overlying epidermis. The eruption ran a chronic course from several months to years.Limitations:
Direct immunofluorescence could not be performed except in one case. Immunohistochemical stains for CD4 and CD8 could not be done owing to nonavailability. Phototesting was undertaken in one patient only.Conclusion:
Small grouped papules on the nose and adjoining skin with a lichenoid histopathology appear to represent a distinct clinicopathological entity. It may be related to actinic lichen nitidus/micropapular variant of polymorphous light eruption.
النص الكامل:
1
الفهرس:
IMSEAR
مجلة:
Indian J Dermatol Venereol Leprol
السنة:
2019
نوع:
Article