Estimation of single-strand breaks induced in the dried film of DNA by high energy alpha particle from a cyclotron.
Indian J Biochem Biophys
; 1996 Feb; 33(1): 35-8
Article
ي En
| IMSEAR
| ID: sea-26262
ABSTRACT
DNA extracted and purified from Vibrio cholerae OGAWA 154 cells and prepared in the form of a dry thin film was exposed in air to a beam of alpha particles obtained from a Variable Energy Cyclotron. The number of single-strand breaks per DNA unit exhibited a linear dose-effect relationship indicating the occurrence of single-hit kinetics. The efficiency and yield of alpha-induced single-strand breaks were approximately 72 eV/break and 1.39 respectively.
النص الكامل:
1
الفهرس:
IMSEAR
الموضوع الرئيسي:
Vibrio cholerae
/
DNA Damage
/
DNA, Bacterial
/
DNA, Single-Stranded
/
Cyclotrons
/
Alpha Particles
اللغة:
En
مجلة:
Indian J Biochem Biophys
السنة:
1996
نوع:
Article