Mycobacterium tuberculosis infection among HIV/AIDS patients in Thailand: clinical manifestations and outcomes.
Southeast Asian J Trop Med Public Health
; 2002 Jun; 33(2): 346-51
Article
ي En
| IMSEAR
| ID: sea-35196
ABSTRACT
A one year retrospective study, was conducted at Bamrasnaradura Hospital, Nonthaburi Province, Bangkok, Thailand, of 271 subjects with both TB and HIV/AIDS. Single males (median age group 31 to 40 years) were most likely to develop co-infection. The commonest clinical manifestations on initial presentation included a low grade fever, cough, weight loss, lymphadenopathy with pancytopenia, and lung infiltrates. Multi-drug resistant TB (MDR-TB) was found in 26.6% of the subjects which was significantly associated with a past history of anti-TB treatment (p = 0.005; OR=2.5); it was also significantly associated with disseminated TB (p = 0.022; OR=1.9) and mortality (p= 0.013; OR=2.8). Analysis of clinical outcomes showed that 46.7% were lost to follow-up and 13.3% had died by the time of follow-up. Among those who survived, only 11.4% had been successfully treated; the rest had not improved due to relapse (2.9%), therapeutic failure (8.8%), treatment in progress (5.9%), and failure to complete treatment (10.7%).
النص الكامل:
1
الفهرس:
IMSEAR
الموضوع الرئيسي:
Thailand
/
Tuberculosis
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Female
/
Humans
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Male
/
Retrospective Studies
/
Treatment Outcome
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AIDS-Related Opportunistic Infections
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Tuberculosis, Multidrug-Resistant
/
Adult
نوع الدراسة:
Observational_studies
البلد/الأقليم حسب الموضوع:
Asia
اللغة:
En
مجلة:
Southeast Asian J Trop Med Public Health
السنة:
2002
نوع:
Article