Seroepidemiology and genotypes of hepatitis C virus in Thailand.
Asian Pac J Allergy Immunol
; 2007 Jun-Sep; 25(2-3): 175-82
Article
ي En
| IMSEAR
| ID: sea-36810
ABSTRACT
HCV can be classified into 6 major genotypes based on the phylogenetic analysis of the genomic sequences. The 3 major genotypes found in Thailand are 3, 1 and 6, respectively. In 2004, an epidemiological survey was carried out to evaluate the seroprevalence of HCV infections among populations aged 2-60 years in four provinces of Thailand, representing the North, Northeast, Center and South of the country, respectively. One hundred and twenty five out of 5,825 serum samples (2.15%) were positive for anti-HCV by ELISA. Fifty eight out of 100 anti-HCV positive samples (58.0%) were positive by RT-PCR of the 5'UTR. The core region of 45 representative samples was sequenced allowing classification into genotype variants 1a (6.7%), 1b (26.7%), 2a (2.2%), 2c (2.2%), 3a (51.1%), 3b (2.2%) and 6 (8.9%). This information might be crucial for public health surveillance and prevention of HCV infection.
النص الكامل:
1
الفهرس:
IMSEAR
الموضوع الرئيسي:
Phylogeny
/
Thailand
/
Female
/
Humans
/
Male
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Molecular Sequence Data
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Seroepidemiologic Studies
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Child
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Child, Preschool
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Adolescent
البلد/الأقليم حسب الموضوع:
Asia
اللغة:
En
مجلة:
Asian Pac J Allergy Immunol
السنة:
2007
نوع:
Article