Effect of Emblica officinalis Gaertn. (Indian gooseberry) fruit extract on sodium azide and 4-nitro-o-phenylenediamine induced mutagenesis in Salmonella typhimurium.
Indian J Exp Biol
; 1989 Mar; 27(3): 207-9
Article
ي En
| IMSEAR
| ID: sea-56406
ABSTRACT
Water, acetone and chloroform extracts of E. officinalis fruit reduced sodium azide and NPD induced his+ revertants significantly in TA100 and TA97 a strains respectively of S. typhimurium. The chloroform extract was less active as compared to water and acetone extracts. Autoclaving of water extract for 15 min did not reduce its activity. The enhanced inhibitory activity of the extracts on pre-incubation suggests the possibility of desmutagens in the extracts. Besides ascorbic acid, a constituent of the extract, the role of other antimutagenic factors in the extract cannot be ruled out.
النص الكامل:
1
الفهرس:
IMSEAR
الموضوع الرئيسي:
Phenylenediamines
/
Salmonella typhimurium
/
Azides
/
Plant Extracts
/
Carcinogens
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Sodium Azide
/
Fruit
/
Mutagenicity Tests
/
Mutation
اللغة:
En
مجلة:
Indian J Exp Biol
السنة:
1989
نوع:
Article