Effect of experimental diabetes on the activities of hexokinase, glucose-6-phosphate dehydrogenase and catecholamines in rat erythrocytes of different ages.
Indian J Exp Biol
; 1997 Jul; 35(7): 792-5
Article
ي En
| IMSEAR
| ID: sea-59633
ABSTRACT
Hexokinase and glucose-6-phosphate dehydrogenase were assayed in various circulating age fractions i.e., young, middle-aged and old red cell from control, diabetic and insulin-treated diabetic rats. An increase in the activity of hexokinase was observed in three age-wise separated fractions of red cells from diabetic animals in comparison to control. The activity of glucose-6-phosphate dehydrogenase on the other hand decreased in separated ageing fractions of diabetic red cells when compared to control. Reversal of these two enzymes were observed in insulin-treated diabetic rats. The levels of glycosylated haemoglobin and catecholamines were found to increase with ageing red cells in controls and also increased in red cells plasma.
النص الكامل:
1
الفهرس:
IMSEAR
الموضوع الرئيسي:
Rats
/
Female
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Catecholamines
/
Rats, Wistar
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Diabetes Mellitus, Experimental
/
Erythrocyte Aging
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Glucosephosphate Dehydrogenase
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Hexokinase
/
Animals
اللغة:
En
مجلة:
Indian J Exp Biol
السنة:
1997
نوع:
Article