Effect of intravenous quinine on capillary glucose levels in malaria.
Article
ي En
| IMSEAR
| ID: sea-93308
ABSTRACT
OBJECTIVE:
Hypoglycemia occurring during management in patients of severe malaria is often overlooked, which can be associated with higher morbidity and mortality rates.METHOD:
Capillary glucose was estimated in 32 patients of malaria before, at one hour and at six hours of quinine administration. Quinine was given in saline solution intravenously.RESULTS:
Pretreatment capillary glucose was found to be lower (71-80 mg/dl) in 12.5% cases. After one hour of intravenous quinine administration, capillary glucose levels fell by 11.84% in all the cases. A further fall of 20.50% was observed in 75% of cases after six hour. Two patients died and both were suffering from cerebral malaria. Statistically, fall in capillary glucose was highly significant at one hour (t=9.4, p < 0.001) and at six hours. (t=3.87, p < 0.001)CONCLUSION:
Statistically significant fall in capillary glucose levels has been observed in patients of malaria with quinine administration.
النص الكامل:
1
الفهرس:
IMSEAR
الموضوع الرئيسي:
Quinine
/
Blood Glucose
/
Female
/
Humans
/
Male
/
Capillaries
/
Survival Rate
/
Probability
/
Follow-Up Studies
/
Malaria, Vivax
نوع الدراسة:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
البلد/الأقليم حسب الموضوع:
Asia
اللغة:
En
السنة:
2001
نوع:
Article