Anti-migratory effects of Piper betle leaf aqueous extract on cancer cells and its microtubule targeting properties / 浙江大学学报(英文版)(B辑:生物医学和生物技术)
Journal of Zhejiang University. Science. B
; (12): 745-748, 2020.
Article
ي En
| WPRIM
| ID: wpr-1010553
المكتبة المسؤولة:
WPRO
ABSTRACT
Piper betle (PB), also known as "betel" in Malay language, is a tropical Asian vine. PB leaves are commonly chewed by Asians along with betel quid. It contains phenols such as eugenol and hydroxychavicol along with chlorophyll, β-carotene, and vitamin C (Salehi et al., 2019). Extracts from PB leaves have various medicinal properties including anticancer, antioxidant, anti-inflammatory, and antibacterial effects (Salehi et al., 2019). Previous research has shown that PB induces cell cycle arrest at late S or G2/M phase and causes apoptosis at higher doses (Wu et al., 2014; Guha Majumdar and Subramanian, 2019). A combination of PB leaf extract has also been shown to enhance the cytotoxicity of the anticancer drug, 5-fluorouracil (5-FU), in cancer cells (Ng et al., 2014).
Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Plant Extracts
/
Cell Movement
/
Plant Leaves
/
HT29 Cells
/
Piper betle
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Microtubules
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Antineoplastic Agents, Phytogenic
المحددات:
Humans
اللغة:
En
مجلة:
Journal of Zhejiang University. Science. B
السنة:
2020
نوع:
Article