Your browser doesn't support javascript.
loading
Mechanism of Fufang Congrong Yizhi Capsules in treatment of mild cognitive impairment based on network pharmacology / 中国药理学通报
Chinese Pharmacological Bulletin ; (12): 334-343, 2024.
Article ي Zh | WPRIM | ID: wpr-1013626
المكتبة المسؤولة: WPRO
ABSTRACT
Aim To predict the mechanism of Fufang Congrong Yizhi Capsules (FCYC) in the treatment of mild cognitive impairment (MCI) by network pharmacology method, and further validate it in combination with cellular experiments. Methods TCMSP, Gene-Cards, OMIM and TTD databases, Chinese Pharmacopoeia and related literature were used to screen the active ingredients of FCYC and the targets of MCI treatment. The TCM-compound-target-disease network and PPI of intersection targets were constructed, and the GO and KEGG analysis were performed by the Ehamb bioinformation platform. GO and KEGG analysis were performed through Yihanbo biological information platform. Cell model of MCI was established by PC-12 injury induced by Aβ
Key words
النص الكامل: 1 الفهرس: WPRIM اللغة: Zh مجلة: Chinese Pharmacological Bulletin السنة: 2024 نوع: Article
النص الكامل: 1 الفهرس: WPRIM اللغة: Zh مجلة: Chinese Pharmacological Bulletin السنة: 2024 نوع: Article