Nuclear factor-KB signaling pathway and gender differences in alcoholic liver fibrosis / 解剖学报
Acta Anatomica Sinica
; (6): 55-61, 2024.
Article
ي Zh
| WPRIM
| ID: wpr-1015142
المكتبة المسؤولة:
WPRO
ABSTRACT
Objective To investigate the relationship between nuclear factor(NF)-κB signaling pathway and gender differences in alcoholic liver fibrosis. Methods C57BL/6 N mice at 7-8 weeks of age were randomly divided into: male normal group, male model group, female normal group and female model group of 20 mice each. The normal group was fed with control liquid diet for 8 weeks, and the model group was fed with alcoholic liquid diet for 8 weeks combined with 31.5% ethanol gavage (5g/kg twice a week) to establish an alcoholic liver fibrosis model. The mice were executed at the end of 8 weekends, and the alanine aminotransferase (ALT), aspartate aminotransferase (AST) activity, estradiol (E
النص الكامل:
1
الفهرس:
WPRIM
اللغة:
Zh
مجلة:
Acta Anatomica Sinica
السنة:
2024
نوع:
Article