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Research progress of Mendelian randomization in ocular diseases / 国际眼科杂志(Guoji Yanke Zazhi)
International Eye Science ; (12): 784-789, 2024.
Article ي Zh | WPRIM | ID: wpr-1016596
المكتبة المسؤولة: WPRO
ABSTRACT
Etiological research is necessary for understanding the occurrence and epidemiological patterns of diseases, and is also a prerequisite for the diagnosis, prevention and treatment of clinical diseases. Mendelian randomization(MR), a method of research that combines genetics and epidemiology, has the advantage of exploring the causal relationship between exposure and disease genetically as well as avoiding confounding factors and reverse causation. Thus, it has been extensively utilized in the etiological study of diseases. This paper reviews the implementation of MR in the research of ocular diseases and provides ideas and approaches for the investigation of related mechanisms as well as the development of intervention strategies.
Key words
النص الكامل: 1 الفهرس: WPRIM اللغة: Zh مجلة: International Eye Science السنة: 2024 نوع: Article
النص الكامل: 1 الفهرس: WPRIM اللغة: Zh مجلة: International Eye Science السنة: 2024 نوع: Article